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The map label for this gene is aidB [H]

Identifier: 120608852

GI number: 120608852

Start: 158023

End: 159690

Strand: Reverse

Name: aidB [H]

Synonym: Aave_0144

Alternate gene names: 120608852

Gene position: 159690-158023 (Counterclockwise)

Preceding gene: 120608853

Following gene: 120608851

Centisome position: 2.98

GC content: 72.48

Gene sequence:

>1668_bases
ATGGCCCAGGCCACCCACGAGGTTTTCAACCAATACGCCGAGCTGGCCGACTACGACCTGCTCGCCACCGACGCCGCGCT
GCAGGAGGCATTGCAGCGCGCGGGCGCCGCCCATGCCCTGCCCGCGCTGGGCGACTACGCCCGCCGGCTCGGAAGCGCCG
GCACCCATGCCCTGGCCGAGCTGGCCAACCGCCACACACCCATCCTGCACCGCTTCGACAGCCGGGGCCGGCGCGCCGAC
CGGGTGGAGTTCCACCCTGCCTGGGACGCGCTCATGGCGCTCTACCGCGGCGAGGGGCTGGTCTCCATGCCTTTCGACAG
CGACCGGCCCGGCCGCTGGTCCGCCTGGGCCGCCGGCTTCTACCTGCACGGGCAGGTGGAGCAGGGCACGCTCTGCCCGG
CCACGATGACGCAGGCGGCCATCCCATTGCTGCGCAAGGAGCCCGCGCTCTGGGCACGGTTGGGAGACAGGCTCCACAGC
CGCACCCATGATCCGCGCGAGGCGCCCGCGCATGAAAAAGCCGGCATCTGGCTGGGCATGGGCATGACGGAAAAACAGGG
CGGCTCCGACGTGCGCGCCAACACCACCGTGGCCACGCCCCTCGGCGCGGGCGGGCGCGGCGGCGAATACCGGCTGCGCG
GCCACAAGTGGTTCTTCTCCACCCCGCAGAGCGACGCACACCTGGTGGTGGCGCGCACGGGCGAAGGCGGCCCCTTCGCC
TGCTTCTACGTGCCGCGCCGCCTGCAGGACGGCACGCTCAACGGCGTGCACGTGCAGCGCCTGAAAGACAAGGTGGGCAA
CCGCAGCAACGCCAGCGCGGAGGTCGAGTTCCACGATGCCTGGGGCGTGCTCATGGGCGAGGAGGGCCGCGGCATTCCCA
CCATCATCGAGATGGCCACCTATACCCGCCTCAACTGCGTGGCCGGCAGCGCCGCCATCCTGCGGCAGGCCACAGTGCAG
GCCATCGCGTACGCGCGCCGGCGCCACGCCTTCGGCAAGGCCCTGGCCGAGCAGCCCCTCATGCGCACCGTGCTCGCCGA
CCTGGCGCTGGAGAGCGAGGCCGCGCTCGCCCTGCTGATGCGGCTGGCCGAGGCTTTCGAGCGCGATGCCGACGGCACCG
CCACCCCGGCCGACCGTGCCTGGAAGCGCGTGATGACACCGGCCGCCAAGTTCTGGGTCTGCAAGCGCGGCGTGGAGATG
GCGGGCGAAGCGATGGAAGTGTTCGGCGGCAACGGCTACGTGCAGGAGGGCGTGATGGCCCGCCTCTTCCTCGAGGCGCC
CGTCAACTCCATCTGGGAAGGCTCGGGCAACGTGATGTGCCTGGATGTGCTGCGGGCGCTGGCGCGCGACACCGAGGCCG
CCCATGCCCTGCTGGAAGAGTTCGCACCCGCCGCGCAGGGCGAACCGCGCATCGGAGCCACGCTGCGCGAGCTGCAGGCA
CTGCTGGCGCTGCCGCCACAGGAGCTGGAAGGCATGGGCCGCCTCGCCGCCCAGCGCCTGGTGTTGGCCGCCCAGGCCTG
CCTGCTGCGCCGGCACGCCCCCGCGGCCGTGGCCGACGCGTTCATCGCCACCCGTCTCGGCGATGCGGGTGGCGGGCGCG
TGGCCGGAGCGATCGATGCGCGCGCCATCGCAGTGGACGCGATCCTGCAGCGGGCCTGCCCCGCGTAA

Upstream 100 bases:

>100_bases
CTCCGGGCCGGTGTCCTGAAAGCGCGTGCAGGCCCGGGCGAGTGCGGGCACCATGGAGGCTTCGGCGCACGCCGCCGCAT
CCCTGTGGAGGAGACACACC

Downstream 100 bases:

>100_bases
GCCCGAGCGGGGACTTCCCCTTCGCGCCAGCGCGCGGGACTTCGCGGCTCAGGTCGCCGAATGGCCGGCACGGTCCCACC
ATGGATGACAAGCCAGCCGT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MAQATHEVFNQYAELADYDLLATDAALQEALQRAGAAHALPALGDYARRLGSAGTHALAELANRHTPILHRFDSRGRRAD
RVEFHPAWDALMALYRGEGLVSMPFDSDRPGRWSAWAAGFYLHGQVEQGTLCPATMTQAAIPLLRKEPALWARLGDRLHS
RTHDPREAPAHEKAGIWLGMGMTEKQGGSDVRANTTVATPLGAGGRGGEYRLRGHKWFFSTPQSDAHLVVARTGEGGPFA
CFYVPRRLQDGTLNGVHVQRLKDKVGNRSNASAEVEFHDAWGVLMGEEGRGIPTIIEMATYTRLNCVAGSAAILRQATVQ
AIAYARRRHAFGKALAEQPLMRTVLADLALESEAALALLMRLAEAFERDADGTATPADRAWKRVMTPAAKFWVCKRGVEM
AGEAMEVFGGNGYVQEGVMARLFLEAPVNSIWEGSGNVMCLDVLRALARDTEAAHALLEEFAPAAQGEPRIGATLRELQA
LLALPPQELEGMGRLAAQRLVLAAQACLLRRHAPAAVADAFIATRLGDAGGGRVAGAIDARAIAVDAILQRACPA

Sequences:

>Translated_555_residues
MAQATHEVFNQYAELADYDLLATDAALQEALQRAGAAHALPALGDYARRLGSAGTHALAELANRHTPILHRFDSRGRRAD
RVEFHPAWDALMALYRGEGLVSMPFDSDRPGRWSAWAAGFYLHGQVEQGTLCPATMTQAAIPLLRKEPALWARLGDRLHS
RTHDPREAPAHEKAGIWLGMGMTEKQGGSDVRANTTVATPLGAGGRGGEYRLRGHKWFFSTPQSDAHLVVARTGEGGPFA
CFYVPRRLQDGTLNGVHVQRLKDKVGNRSNASAEVEFHDAWGVLMGEEGRGIPTIIEMATYTRLNCVAGSAAILRQATVQ
AIAYARRRHAFGKALAEQPLMRTVLADLALESEAALALLMRLAEAFERDADGTATPADRAWKRVMTPAAKFWVCKRGVEM
AGEAMEVFGGNGYVQEGVMARLFLEAPVNSIWEGSGNVMCLDVLRALARDTEAAHALLEEFAPAAQGEPRIGATLRELQA
LLALPPQELEGMGRLAAQRLVLAAQACLLRRHAPAAVADAFIATRLGDAGGGRVAGAIDARAIAVDAILQRACPA
>Mature_554_residues
AQATHEVFNQYAELADYDLLATDAALQEALQRAGAAHALPALGDYARRLGSAGTHALAELANRHTPILHRFDSRGRRADR
VEFHPAWDALMALYRGEGLVSMPFDSDRPGRWSAWAAGFYLHGQVEQGTLCPATMTQAAIPLLRKEPALWARLGDRLHSR
THDPREAPAHEKAGIWLGMGMTEKQGGSDVRANTTVATPLGAGGRGGEYRLRGHKWFFSTPQSDAHLVVARTGEGGPFAC
FYVPRRLQDGTLNGVHVQRLKDKVGNRSNASAEVEFHDAWGVLMGEEGRGIPTIIEMATYTRLNCVAGSAAILRQATVQA
IAYARRRHAFGKALAEQPLMRTVLADLALESEAALALLMRLAEAFERDADGTATPADRAWKRVMTPAAKFWVCKRGVEMA
GEAMEVFGGNGYVQEGVMARLFLEAPVNSIWEGSGNVMCLDVLRALARDTEAAHALLEEFAPAAQGEPRIGATLRELQAL
LALPPQELEGMGRLAAQRLVLAAQACLLRRHAPAAVADAFIATRLGDAGGGRVAGAIDARAIAVDAILQRACPA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=282, Percent_Identity=25.177304964539, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI226958414, Length=282, Percent_Identity=25.177304964539, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI7656849, Length=275, Percent_Identity=25.8181818181818, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4501857, Length=278, Percent_Identity=25.1798561151079, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4557233, Length=276, Percent_Identity=25.3623188405797, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI4557231, Length=275, Percent_Identity=25.8181818181818, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI187960098, Length=275, Percent_Identity=25.8181818181818, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082384, Length=540, Percent_Identity=46.4814814814815, Blast_Score=427, Evalue=1e-120,
Organism=Escherichia coli, GI1786223, Length=271, Percent_Identity=25.0922509225092, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=422, Percent_Identity=30.5687203791469, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI86563381, Length=422, Percent_Identity=30.5687203791469, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=278, Percent_Identity=26.978417266187, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=280, Percent_Identity=26.4285714285714, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=276, Percent_Identity=28.9855072463768, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=282, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=346, Percent_Identity=26.5895953757225, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=270, Percent_Identity=24.8148148148148, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355753, Length=265, Percent_Identity=26.4150943396226, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356377, Length=289, Percent_Identity=25.9515570934256, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59800; Mature: 59669

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQATHEVFNQYAELADYDLLATDAALQEALQRAGAAHALPALGDYARRLGSAGTHALAE
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCHHHHHH
LANRHTPILHRFDSRGRRADRVEFHPAWDALMALYRGEGLVSMPFDSDRPGRWSAWAAGF
HHHCCCHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCCEEECCCCCCCCCCCHHEEECE
YLHGQVEQGTLCPATMTQAAIPLLRKEPALWARLGDRLHSRTHDPREAPAHEKAGIWLGM
EEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GMTEKQGGSDVRANTTVATPLGAGGRGGEYRLRGHKWFFSTPQSDAHLVVARTGEGGPFA
CCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEECCEEEECCCCCCCEEEEEEECCCCCEE
CFYVPRRLQDGTLNGVHVQRLKDKVGNRSNASAEVEFHDAWGVLMGEEGRGIPTIIEMAT
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHH
YTRLNCVAGSAAILRQATVQAIAYARRRHAFGKALAEQPLMRTVLADLALESEAALALLM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RLAEAFERDADGTATPADRAWKRVMTPAAKFWVCKRGVEMAGEAMEVFGGNGYVQEGVMA
HHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RLFLEAPVNSIWEGSGNVMCLDVLRALARDTEAAHALLEEFAPAAQGEPRIGATLRELQA
HHHHHHCHHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LLALPPQELEGMGRLAAQRLVLAAQACLLRRHAPAAVADAFIATRLGDAGGGRVAGAIDA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECHHH
RAIAVDAILQRACPA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQATHEVFNQYAELADYDLLATDAALQEALQRAGAAHALPALGDYARRLGSAGTHALAE
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCHHHHHH
LANRHTPILHRFDSRGRRADRVEFHPAWDALMALYRGEGLVSMPFDSDRPGRWSAWAAGF
HHHCCCHHHHHHHCCCCCCCCEEECHHHHHHHHHHCCCCEEECCCCCCCCCCCHHEEECE
YLHGQVEQGTLCPATMTQAAIPLLRKEPALWARLGDRLHSRTHDPREAPAHEKAGIWLGM
EEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GMTEKQGGSDVRANTTVATPLGAGGRGGEYRLRGHKWFFSTPQSDAHLVVARTGEGGPFA
CCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEECCEEEECCCCCCCEEEEEEECCCCCEE
CFYVPRRLQDGTLNGVHVQRLKDKVGNRSNASAEVEFHDAWGVLMGEEGRGIPTIIEMAT
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHH
YTRLNCVAGSAAILRQATVQAIAYARRRHAFGKALAEQPLMRTVLADLALESEAALALLM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
RLAEAFERDADGTATPADRAWKRVMTPAAKFWVCKRGVEMAGEAMEVFGGNGYVQEGVMA
HHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RLFLEAPVNSIWEGSGNVMCLDVLRALARDTEAAHALLEEFAPAAQGEPRIGATLRELQA
HHHHHHCHHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LLALPPQELEGMGRLAAQRLVLAAQACLLRRHAPAAVADAFIATRLGDAGGGRVAGAIDA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEECHHH
RAIAVDAILQRACPA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]