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The map label for this gene is gbpR [H]

Identifier: 120608853

GI number: 120608853

Start: 159772

End: 160695

Strand: Reverse

Name: gbpR [H]

Synonym: Aave_0145

Alternate gene names: 120608853

Gene position: 160695-159772 (Counterclockwise)

Preceding gene: 120608859

Following gene: 120608852

Centisome position: 3.0

GC content: 71.32

Gene sequence:

>924_bases
ATGGATTGGACCCACCGCCTGCGGCTGCGCCAGCTGCAGATGCTCCTCAGCCTCGCGCAGACCGGCAACATGAGCCAGTC
GGCGCAGCAGCTGCACACCGCGCAGCCCGCGCTCTCCAAATGGCTCAGGGAACTGGAGGACGATCTGGGGATGGTGCTGT
TCGAGCGCCATGCACGCGGCCTGCGGCCCACGCCCCAGGGCGAGGCGCTGATCGCCCATGCCCGGCGCATCGAGGCCCAC
CTGGACAGCGCCCGCGACGACATGCAGGCCCTGCGCGACGGCGGCAGCGGCCTGGTCGTCGTGGGCACCTCGGGCGCATC
CGCCTCCGACGTGGTGCCCATGGCCGTGCTGCGCCTGCTGGAATGGCTGCCGCGCGCCCAGGTCCGGCTCGCCGAGAGCA
CCATGAACGTGCTCATGCAACAGCTGGCCATGGGCGAGCTGGACGTGGTGGTGGGCCGCTCCGCCCCCGAACTGCACGAC
ACCCACATCCACGCCGAGACGCTCTACATGGAGCCCATCCACCTGGTGGCGCGCCCCCAGCACCCGCTGCTGCAGCGCAC
GGAAGGCCCGATCGACTGGCCCGACCTGATGGCCTGGCGCTGGCTGGTCTGGCCGCGCGGCACGCCCATCCGCAACGCGC
TGGAAAACGCCCTCGTCGCCGCCGGCCACGCGCTGCCGCCGGGCAGCGTGGAATCCAACTCCGTCACGCTCAACCTCACC
CTGCTGGGACACAGCGACATGATCGGCCTGGCCTCGCACCGGGCAGCGCTGCGCTTCTCGCACATGGGTGCGCTGCGCGT
GCTGCCGGTGCGGCTGTCGGGTTTCGGATCGGTGTCGATGTACTGGCGCGAGAACACCACCGACCGCACGGCCGTGGCCA
CCATGCTGCGCGCCCTGCGCGAGGTCTCCGGGCCGGTGTCCTGA

Upstream 100 bases:

>100_bases
TGCCATGGAGTCCATTATTCGAGGCGAGCGATAGTCCGTAAAATCATTTATTGGTCTTATTCATAATTTTTTGGATATAC
CTTCTTCCAGGACCGCCGCC

Downstream 100 bases:

>100_bases
AAGCGCGTGCAGGCCCGGGCGAGTGCGGGCACCATGGAGGCTTCGGCGCACGCCGCCGCATCCCTGTGGAGGAGACACAC
CATGGCCCAGGCCACCCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDWTHRLRLRQLQMLLSLAQTGNMSQSAQQLHTAQPALSKWLRELEDDLGMVLFERHARGLRPTPQGEALIAHARRIEAH
LDSARDDMQALRDGGSGLVVVGTSGASASDVVPMAVLRLLEWLPRAQVRLAESTMNVLMQQLAMGELDVVVGRSAPELHD
THIHAETLYMEPIHLVARPQHPLLQRTEGPIDWPDLMAWRWLVWPRGTPIRNALENALVAAGHALPPGSVESNSVTLNLT
LLGHSDMIGLASHRAALRFSHMGALRVLPVRLSGFGSVSMYWRENTTDRTAVATMLRALREVSGPVS

Sequences:

>Translated_307_residues
MDWTHRLRLRQLQMLLSLAQTGNMSQSAQQLHTAQPALSKWLRELEDDLGMVLFERHARGLRPTPQGEALIAHARRIEAH
LDSARDDMQALRDGGSGLVVVGTSGASASDVVPMAVLRLLEWLPRAQVRLAESTMNVLMQQLAMGELDVVVGRSAPELHD
THIHAETLYMEPIHLVARPQHPLLQRTEGPIDWPDLMAWRWLVWPRGTPIRNALENALVAAGHALPPGSVESNSVTLNLT
LLGHSDMIGLASHRAALRFSHMGALRVLPVRLSGFGSVSMYWRENTTDRTAVATMLRALREVSGPVS
>Mature_307_residues
MDWTHRLRLRQLQMLLSLAQTGNMSQSAQQLHTAQPALSKWLRELEDDLGMVLFERHARGLRPTPQGEALIAHARRIEAH
LDSARDDMQALRDGGSGLVVVGTSGASASDVVPMAVLRLLEWLPRAQVRLAESTMNVLMQQLAMGELDVVVGRSAPELHD
THIHAETLYMEPIHLVARPQHPLLQRTEGPIDWPDLMAWRWLVWPRGTPIRNALENALVAAGHALPPGSVESNSVTLNLT
LLGHSDMIGLASHRAALRFSHMGALRVLPVRLSGFGSVSMYWRENTTDRTAVATMLRALREVSGPVS

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=301, Percent_Identity=29.2358803986711, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787601, Length=266, Percent_Identity=24.0601503759398, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=194, Percent_Identity=24.7422680412371, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=223, Percent_Identity=25.1121076233184, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=30.8219178082192, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790399, Length=216, Percent_Identity=26.8518518518519, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=261, Percent_Identity=24.5210727969349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789506, Length=170, Percent_Identity=22.9411764705882, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=230, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=227, Percent_Identity=25.1101321585903, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=174, Percent_Identity=27.0114942528736, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=185, Percent_Identity=27.5675675675676, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367136, Length=157, Percent_Identity=28.0254777070064, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1788481, Length=214, Percent_Identity=25.7009345794392, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33941; Mature: 33941

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWTHRLRLRQLQMLLSLAQTGNMSQSAQQLHTAQPALSKWLRELEDDLGMVLFERHARG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
LRPTPQGEALIAHARRIEAHLDSARDDMQALRDGGSGLVVVGTSGASASDVVPMAVLRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
EWLPRAQVRLAESTMNVLMQQLAMGELDVVVGRSAPELHDTHIHAETLYMEPIHLVARPQ
HHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCEEEHHHEEECCHHHHCCCC
HPLLQRTEGPIDWPDLMAWRWLVWPRGTPIRNALENALVAAGHALPPGSVESNSVTLNLT
CHHHHCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
LLGHSDMIGLASHRAALRFSHMGALRVLPVRLSGFGSVSMYWRENTTDRTAVATMLRALR
EECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHH
EVSGPVS
HHCCCCC
>Mature Secondary Structure
MDWTHRLRLRQLQMLLSLAQTGNMSQSAQQLHTAQPALSKWLRELEDDLGMVLFERHARG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
LRPTPQGEALIAHARRIEAHLDSARDDMQALRDGGSGLVVVGTSGASASDVVPMAVLRLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
EWLPRAQVRLAESTMNVLMQQLAMGELDVVVGRSAPELHDTHIHAETLYMEPIHLVARPQ
HHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCEEEHHHEEECCHHHHCCCC
HPLLQRTEGPIDWPDLMAWRWLVWPRGTPIRNALENALVAAGHALPPGSVESNSVTLNLT
CHHHHCCCCCCCCHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
LLGHSDMIGLASHRAALRFSHMGALRVLPVRLSGFGSVSMYWRENTTDRTAVATMLRALR
EECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHH
EVSGPVS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]