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The map label for this gene is queC

Identifier: 120608847

GI number: 120608847

Start: 149992

End: 150699

Strand: Reverse

Name: queC

Synonym: Aave_0139

Alternate gene names: 120608847

Gene position: 150699-149992 (Counterclockwise)

Preceding gene: 120608848

Following gene: 120608846

Centisome position: 2.82

GC content: 70.48

Gene sequence:

>708_bases
ATGCGAGCCGGCCACGCCCTCGTCCTCTTCTCCGGTGGCCAGGACTCCACCACCTGCCTCGCCTGGGCGCTCGAGCGTTT
CGAACGGGTGGAAACCATCGGCTTCGACTACGGACAGCGCCACCATGTGGAACTGGAGGCGCGTACCGCCGTGCTGGCGG
CGCTGCGCGGCCGTTTCCCCGCCTGGAGCGCGCGCCTGGGCGACGACCACATGGTCGACCTGGCCGTGCTCGGCCAGATC
AGCGACACGGCGCTCACCCGCGACACCGCCATCCAGATGACGGAAGCCGGCCTGCCCAACACCTTCGTGCCGGGCCGCAA
CCTGCTGTTCTTCCAGCTGGCCGCCGCCGTGGGCTACCGGCGCGGGCTGCACACCCTCGTGGGCGGCATGTGCGAGACCG
ACTTCTCCGGCTACCCCGACTGCCGCGACGACACGCTCAAGGCGCTGCAGGTGGCCCTCTCCCTCGGCATGGGCCAGCGC
TTCACCATCGAGACGCCGCTCATGTGGATCGACAAGGCCGAAACCTGGGAAATGGCCCGGCAGCTCGGGGGCGACGAGCT
GGTGCAGCTCATCGTGGAAGACACGCACACCTGCTACCACGGCGTGCGCGGCGCCCTGCACGCCTGGGGACACGGCTGCG
GCGAATGCCCGGCCTGCGCCCTGCGTCGCGCCGGACACGAGCGCTGGACCGCACAGCACACCGCATGA

Upstream 100 bases:

>100_bases
GTACATGGCCTGAAAGCCATCCCCCACCTGCCAGCCGGCCCCGCGCATGCGGGGCTTTTTCTTTTCGCTCCCGCTTTCTT
CTTTTCCAAGGACCCATCCC

Downstream 100 bases:

>100_bases
ACCATACATAACCTCATGCGTCTTTTGCATGGGTTTCCCCCCTATCTGACAGACAGGAAGGGGGTGGATTCATAAAATCG
TCATCCCAGCCGACCTGCGG

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRAGHALVLFSGGQDSTTCLAWALERFERVETIGFDYGQRHHVELEARTAVLAALRGRFPAWSARLGDDHMVDLAVLGQI
SDTALTRDTAIQMTEAGLPNTFVPGRNLLFFQLAAAVGYRRGLHTLVGGMCETDFSGYPDCRDDTLKALQVALSLGMGQR
FTIETPLMWIDKAETWEMARQLGGDELVQLIVEDTHTCYHGVRGALHAWGHGCGECPACALRRAGHERWTAQHTA

Sequences:

>Translated_235_residues
MRAGHALVLFSGGQDSTTCLAWALERFERVETIGFDYGQRHHVELEARTAVLAALRGRFPAWSARLGDDHMVDLAVLGQI
SDTALTRDTAIQMTEAGLPNTFVPGRNLLFFQLAAAVGYRRGLHTLVGGMCETDFSGYPDCRDDTLKALQVALSLGMGQR
FTIETPLMWIDKAETWEMARQLGGDELVQLIVEDTHTCYHGVRGALHAWGHGCGECPACALRRAGHERWTAQHTA
>Mature_235_residues
MRAGHALVLFSGGQDSTTCLAWALERFERVETIGFDYGQRHHVELEARTAVLAALRGRFPAWSARLGDDHMVDLAVLGQI
SDTALTRDTAIQMTEAGLPNTFVPGRNLLFFQLAAAVGYRRGLHTLVGGMCETDFSGYPDCRDDTLKALQVALSLGMGQR
FTIETPLMWIDKAETWEMARQLGGDELVQLIVEDTHTCYHGVRGALHAWGHGCGECPACALRRAGHERWTAQHTA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=230, Percent_Identity=44.7826086956522, Blast_Score=197, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ACIAC (A1TIG3)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968525.1
- ProteinModelPortal:   A1TIG3
- SMR:   A1TIG3
- STRING:   A1TIG3
- GeneID:   4666251
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0139
- NMPDR:   fig|397945.5.peg.121
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   A1TIG3
- ProtClustDB:   CLSK864419
- BioCyc:   AAVE397945:AAVE_0139-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25880; Mature: 25880

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGHALVLFSGGQDSTTCLAWALERFERVETIGFDYGQRHHVELEARTAVLAALRGRFP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCC
AWSARLGDDHMVDLAVLGQISDTALTRDTAIQMTEAGLPNTFVPGRNLLFFQLAAAVGYR
CCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RGLHTLVGGMCETDFSGYPDCRDDTLKALQVALSLGMGQRFTIETPLMWIDKAETWEMAR
HHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHH
QLGGDELVQLIVEDTHTCYHGVRGALHAWGHGCGECPACALRRAGHERWTAQHTA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MRAGHALVLFSGGQDSTTCLAWALERFERVETIGFDYGQRHHVELEARTAVLAALRGRFP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCC
AWSARLGDDHMVDLAVLGQISDTALTRDTAIQMTEAGLPNTFVPGRNLLFFQLAAAVGYR
CCCCCCCCCCEEHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RGLHTLVGGMCETDFSGYPDCRDDTLKALQVALSLGMGQRFTIETPLMWIDKAETWEMAR
HHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHH
QLGGDELVQLIVEDTHTCYHGVRGALHAWGHGCGECPACALRRAGHERWTAQHTA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA