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The map label for this gene is nahR [H]

Identifier: 120608844

GI number: 120608844

Start: 146060

End: 147061

Strand: Reverse

Name: nahR [H]

Synonym: Aave_0136

Alternate gene names: 120608844

Gene position: 147061-146060 (Counterclockwise)

Preceding gene: 120608846

Following gene: 120608843

Centisome position: 2.75

GC content: 72.06

Gene sequence:

>1002_bases
ATGCAGCCCATCAATTTCCGCTCGCTCGACCTGAATCTCCTGCGCGTCTTCGACGAGGTCATGGCCGAGCGCAACCTCAC
CCGCGCCGCCGCCAAGCTCGCGCTCACGCAGCCCGCGGTGAGCAACGCCCTGCGACGCCTGCGCGAGGTGGTGGGCGACG
ATCTCGTGGTGCGCAGCGGGCAGGGCGTGGAGCCCACGCCCCGGGCCCTGGCCCTCTGGCCCCCGGTACGGCAGGCGCTG
GCCCAACTGCAGCAGTCGCTGGCGCCAGGGGCTTTCGATCCGGCCTCGGCCAATTCCACCTTCGTGCTCGCGCTGGCCGA
TGCCACCGGCGCCACGCTCATCCCCCCGCTGGTGGAGATCGTGGAGCGCGAGGCGCCCGGCGTGTCGCTGCGCGTGGTGC
CGCTCACCACGCGCGACCCGCGCAGCCTGCTGGACGACGAATCCACCGACATGGCGGTGGGCTACTTTCCCGCCGTGATG
GCCGACCTCACCGCGCGGGCGCAGACCGACAGCGTGATCGCCTATGACAGCCTGCGGCTCTACGACGGCGAGTATGTCTG
CGTGATGCGCCAGGACCATCCCCTGGCCCGCGAGCCGCTCACGCTGGACCAATACTGCGCGGCGCGCCACCTGCTGGTGA
GCTTTTCCGGCAAGCCCTACGGCTTCATCGACGAGGCCCTGACCGCGCTCGGCCGCGAGCGGCGCATCGTGCTCACGGTG
AACCAGTTCTTCACCGCCGGCCGGGTGGTGGCGACCACCGACCTGCTCACCGTGCTGCCGCGCCACTTCGTGGGCGTGGC
CAGCCTCGGCGGGGAGCTCGTCTGGCGCCCGCTGCCCATGCCGCTGCCCACCGTGCACGTCGATGCGCTCTGGCACCGCC
GCAAGCGCCACGACGCCGCCCACGTCTGGCTGCGGGGTGCCATGGCGCGATCGGCCCAGCACACGGCGGCGCGTCCTCCG
GCAACCGCGGCAGCGCCCGCACCGGAGAATCCGGAGGCATGA

Upstream 100 bases:

>100_bases
GCGAAGTTGCCGGGCGAATGCAGGTATCTTAGGGTTTACCCCATAGCTGTTCCACTTTATATTTTGAATCCCAGACATTC
ACAGCCATGATGATTCAGGC

Downstream 100 bases:

>100_bases
AGATCCAACTGCTGTCCGACCTGCACCTGGAGGCCCATCCCGCATTCCAGCCCAGCCCCGCGCCGGAGGCCGACCTGCTC
GTCCTGGCCGGGGACATCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQPINFRSLDLNLLRVFDEVMAERNLTRAAAKLALTQPAVSNALRRLREVVGDDLVVRSGQGVEPTPRALALWPPVRQAL
AQLQQSLAPGAFDPASANSTFVLALADATGATLIPPLVEIVEREAPGVSLRVVPLTTRDPRSLLDDESTDMAVGYFPAVM
ADLTARAQTDSVIAYDSLRLYDGEYVCVMRQDHPLAREPLTLDQYCAARHLLVSFSGKPYGFIDEALTALGRERRIVLTV
NQFFTAGRVVATTDLLTVLPRHFVGVASLGGELVWRPLPMPLPTVHVDALWHRRKRHDAAHVWLRGAMARSAQHTAARPP
ATAAAPAPENPEA

Sequences:

>Translated_333_residues
MQPINFRSLDLNLLRVFDEVMAERNLTRAAAKLALTQPAVSNALRRLREVVGDDLVVRSGQGVEPTPRALALWPPVRQAL
AQLQQSLAPGAFDPASANSTFVLALADATGATLIPPLVEIVEREAPGVSLRVVPLTTRDPRSLLDDESTDMAVGYFPAVM
ADLTARAQTDSVIAYDSLRLYDGEYVCVMRQDHPLAREPLTLDQYCAARHLLVSFSGKPYGFIDEALTALGRERRIVLTV
NQFFTAGRVVATTDLLTVLPRHFVGVASLGGELVWRPLPMPLPTVHVDALWHRRKRHDAAHVWLRGAMARSAQHTAARPP
ATAAAPAPENPEA
>Mature_333_residues
MQPINFRSLDLNLLRVFDEVMAERNLTRAAAKLALTQPAVSNALRRLREVVGDDLVVRSGQGVEPTPRALALWPPVRQAL
AQLQQSLAPGAFDPASANSTFVLALADATGATLIPPLVEIVEREAPGVSLRVVPLTTRDPRSLLDDESTDMAVGYFPAVM
ADLTARAQTDSVIAYDSLRLYDGEYVCVMRQDHPLAREPLTLDQYCAARHLLVSFSGKPYGFIDEALTALGRERRIVLTV
NQFFTAGRVVATTDLLTVLPRHFVGVASLGGELVWRPLPMPLPTVHVDALWHRRKRHDAAHVWLRGAMARSAQHTAARPP
ATAAAPAPENPEA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=29.9674267100977, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87081766, Length=293, Percent_Identity=25.2559726962457, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=26.158940397351, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786820, Length=297, Percent_Identity=23.2323232323232, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36330; Mature: 36330

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPINFRSLDLNLLRVFDEVMAERNLTRAAAKLALTQPAVSNALRRLREVVGDDLVVRSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECC
QGVEPTPRALALWPPVRQALAQLQQSLAPGAFDPASANSTFVLALADATGATLIPPLVEI
CCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
VEREAPGVSLRVVPLTTRDPRSLLDDESTDMAVGYFPAVMADLTARAQTDSVIAYDSLRL
HHCCCCCCEEEEEEECCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECCEEE
YDGEYVCVMRQDHPLAREPLTLDQYCAARHLLVSFSGKPYGFIDEALTALGRERRIVLTV
ECCCEEEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCCEEEEEE
NQFFTAGRVVATTDLLTVLPRHFVGVASLGGELVWRPLPMPLPTVHVDALWHRRKRHDAA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHH
HVWLRGAMARSAQHTAARPPATAAAPAPENPEA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPINFRSLDLNLLRVFDEVMAERNLTRAAAKLALTQPAVSNALRRLREVVGDDLVVRSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECC
QGVEPTPRALALWPPVRQALAQLQQSLAPGAFDPASANSTFVLALADATGATLIPPLVEI
CCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
VEREAPGVSLRVVPLTTRDPRSLLDDESTDMAVGYFPAVMADLTARAQTDSVIAYDSLRL
HHCCCCCCEEEEEEECCCCHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECCEEE
YDGEYVCVMRQDHPLAREPLTLDQYCAARHLLVSFSGKPYGFIDEALTALGRERRIVLTV
ECCCEEEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCCEEEEEE
NQFFTAGRVVATTDLLTVLPRHFVGVASLGGELVWRPLPMPLPTVHVDALWHRRKRHDAA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCHH
HVWLRGAMARSAQHTAARPPATAAAPAPENPEA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]