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The map label for this gene is rutG [H]

Identifier: 120608811

GI number: 120608811

Start: 106832

End: 108133

Strand: Reverse

Name: rutG [H]

Synonym: Aave_0102

Alternate gene names: 120608811

Gene position: 108133-106832 (Counterclockwise)

Preceding gene: 120608813

Following gene: 120608809

Centisome position: 2.02

GC content: 69.12

Gene sequence:

>1302_bases
GTGTCCACCCCCTCTTCTTCATATTTCACCCGCTGGCGGCTGGCCTCGCCCGCCGAGGGCGCCGTGGTCGCCCCCGACGA
GCGCCTGCCCTGGGGGCACACCGCCGCCATGGGCGTACAGCACGTGATCGCCATGTTCGGGGCCACCGTGCTCGCCCCCA
TCCTCATGGGGTTCGATCCCAACTTGGCCATCCTGATGAGCGGCCTGGGCACGCTGATCTTCTTCCTCGTGACCGGCGGC
CGCGTGCCGAGCTACCTGGGTTCGAGCTTCGCCTTCATCGGCGTGGTGATCGCCGCCACGGGCTATGCCGGCCAGGGACC
GAACGCCAACATAGCCGTGGCGCTGGGCGGCATCATCGCCTGCGGCCTGCTCTACACCGTGATCGGCGCCATCGTGCAGG
CCGTGGGTACGGGCTGGATCGAGCGCTGCATGCCGCCCGTGGTGACGGGCGCGGTGGTCGCGGTGATCGGCCTCAACCTC
GCGCAGGTGCCCATCAAGAACATGGCGGCCAACAATTTCGAGAGCTGGATGCAGGCCGTCACCTTCGTGTGCGTGGGCCT
GGTCGCGGTGCTCACGCGCGGCATGCTGCAGCGGCTGCTGATCCTCGTGGGCCTGATCGCCGCCAGCGTGCTGTACGCGC
TGCTCACCAACGGCCTGGGCCTGGGCAAGCCGATGGACCTCTCCGGCGTGCTGGCCGCGCCCTGGCTGGGCCTGCCGCGC
TTCGCCGCGCCCGCCTTCAGCGCGCCGGCCATGCTGCTGATCGCGCCCGTGGCGGTCATCCTGGTGGCCGAGAACCTCGG
CCATATAAAGGCCGTCACGGCCATGACCGGCCGCAACCTCGACCGCTACATGGGCCGCGCTTTCATCGGGGACGGCATCG
CCACCATGGCGAGCGGCGCGGTGGGCGGCACGGGCGTGACCACGTATGCCGAGAACATCGGGGTGATGGCCGCCACCAAG
ATCTATTCCACCGCCGTGTTCCTCGTGGCCGGGCTGATCGCGCTGGTGCTGGGCTTTTCGCCGAAGTTCGGCGCGCTGAT
CCAGGCCATCCCGCTGCCGGTGATGGGCGGCGTCTCGATCGTGGTGTTCGGCCTCATCGCCGTGGCCGGCGCCAAGATCT
GGGTGGACAACCGCGTGGACTTCTCGGACAACAGGAACCTGATCGTGGCCGCCATCACGCTCATCATCGGCACGGGCGAC
TTCACGCTCAAGTTCGGCGACTTCGCGCTGGGCGGCATCGGCACCGCCACCTTCGGCGCGATCGGGCTCTACGCGCTGCT
GAACCTGCGGCGCGGCCGCTGA

Upstream 100 bases:

>100_bases
TTTCCGCACCACCTTTCCCCACCGCGCCGGCGCGGCCACGCCCTGCCCGCGCGCGGAACACCCGGAACGCCTGCACCCAA
CATCCAAGGAGCCCATCGCC

Downstream 100 bases:

>100_bases
TCCGGGCCTGCAGTCGTTCAGCGCTTCAGCAGCGACCAGACCAGCTCCACCCCGGCCGCGAGCAGGTCGAACCGCTCGGA
GGTGGTGGAGGTGAACGCCT

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSTPSSSYFTRWRLASPAEGAVVAPDERLPWGHTAAMGVQHVIAMFGATVLAPILMGFDPNLAILMSGLGTLIFFLVTGG
RVPSYLGSSFAFIGVVIAATGYAGQGPNANIAVALGGIIACGLLYTVIGAIVQAVGTGWIERCMPPVVTGAVVAVIGLNL
AQVPIKNMAANNFESWMQAVTFVCVGLVAVLTRGMLQRLLILVGLIAASVLYALLTNGLGLGKPMDLSGVLAAPWLGLPR
FAAPAFSAPAMLLIAPVAVILVAENLGHIKAVTAMTGRNLDRYMGRAFIGDGIATMASGAVGGTGVTTYAENIGVMAATK
IYSTAVFLVAGLIALVLGFSPKFGALIQAIPLPVMGGVSIVVFGLIAVAGAKIWVDNRVDFSDNRNLIVAAITLIIGTGD
FTLKFGDFALGGIGTATFGAIGLYALLNLRRGR

Sequences:

>Translated_433_residues
MSTPSSSYFTRWRLASPAEGAVVAPDERLPWGHTAAMGVQHVIAMFGATVLAPILMGFDPNLAILMSGLGTLIFFLVTGG
RVPSYLGSSFAFIGVVIAATGYAGQGPNANIAVALGGIIACGLLYTVIGAIVQAVGTGWIERCMPPVVTGAVVAVIGLNL
AQVPIKNMAANNFESWMQAVTFVCVGLVAVLTRGMLQRLLILVGLIAASVLYALLTNGLGLGKPMDLSGVLAAPWLGLPR
FAAPAFSAPAMLLIAPVAVILVAENLGHIKAVTAMTGRNLDRYMGRAFIGDGIATMASGAVGGTGVTTYAENIGVMAATK
IYSTAVFLVAGLIALVLGFSPKFGALIQAIPLPVMGGVSIVVFGLIAVAGAKIWVDNRVDFSDNRNLIVAAITLIIGTGD
FTLKFGDFALGGIGTATFGAIGLYALLNLRRGR
>Mature_432_residues
STPSSSYFTRWRLASPAEGAVVAPDERLPWGHTAAMGVQHVIAMFGATVLAPILMGFDPNLAILMSGLGTLIFFLVTGGR
VPSYLGSSFAFIGVVIAATGYAGQGPNANIAVALGGIIACGLLYTVIGAIVQAVGTGWIERCMPPVVTGAVVAVIGLNLA
QVPIKNMAANNFESWMQAVTFVCVGLVAVLTRGMLQRLLILVGLIAASVLYALLTNGLGLGKPMDLSGVLAAPWLGLPRF
AAPAFSAPAMLLIAPVAVILVAENLGHIKAVTAMTGRNLDRYMGRAFIGDGIATMASGAVGGTGVTTYAENIGVMAATKI
YSTAVFLVAGLIALVLGFSPKFGALIQAIPLPVMGGVSIVVFGLIAVAGAKIWVDNRVDFSDNRNLIVAAITLIIGTGDF
TLKFGDFALGGIGTATFGAIGLYALLNLRRGR

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=423, Percent_Identity=69.9763593380615, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1788843, Length=416, Percent_Identity=37.7403846153846, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87082181, Length=440, Percent_Identity=26.3636363636364, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790087, Length=404, Percent_Identity=23.2673267326733, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082178, Length=409, Percent_Identity=25.9168704156479, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542260, Length=172, Percent_Identity=34.8837209302326, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=172, Percent_Identity=34.3023255813954, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=172, Percent_Identity=32.5581395348837, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=172, Percent_Identity=29.6511627906977, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44449; Mature: 44318

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPSSSYFTRWRLASPAEGAVVAPDERLPWGHTAAMGVQHVIAMFGATVLAPILMGFDP
CCCCCCCHHEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLAILMSGLGTLIFFLVTGGRVPSYLGSSFAFIGVVIAATGYAGQGPNANIAVALGGIIA
CHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHH
CGLLYTVIGAIVQAVGTGWIERCMPPVVTGAVVAVIGLNLAQVPIKNMAANNFESWMQAV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHCCHHHHHHHH
TFVCVGLVAVLTRGMLQRLLILVGLIAASVLYALLTNGLGLGKPMDLSGVLAAPWLGLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCC
FAAPAFSAPAMLLIAPVAVILVAENLGHIKAVTAMTGRNLDRYMGRAFIGDGIATMASGA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCC
VGGTGVTTYAENIGVMAATKIYSTAVFLVAGLIALVLGFSPKFGALIQAIPLPVMGGVSI
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
VVFGLIAVAGAKIWVDNRVDFSDNRNLIVAAITLIIGTGDFTLKFGDFALGGIGTATFGA
HHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEECCCCCHHHHHH
IGLYALLNLRRGR
HHHHHHHHHHCCC
>Mature Secondary Structure 
STPSSSYFTRWRLASPAEGAVVAPDERLPWGHTAAMGVQHVIAMFGATVLAPILMGFDP
CCCCCCHHEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLAILMSGLGTLIFFLVTGGRVPSYLGSSFAFIGVVIAATGYAGQGPNANIAVALGGIIA
CHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHH
CGLLYTVIGAIVQAVGTGWIERCMPPVVTGAVVAVIGLNLAQVPIKNMAANNFESWMQAV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHCCHHHHHHCCHHHHHHHH
TFVCVGLVAVLTRGMLQRLLILVGLIAASVLYALLTNGLGLGKPMDLSGVLAAPWLGLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCC
FAAPAFSAPAMLLIAPVAVILVAENLGHIKAVTAMTGRNLDRYMGRAFIGDGIATMASGA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCC
VGGTGVTTYAENIGVMAATKIYSTAVFLVAGLIALVLGFSPKFGALIQAIPLPVMGGVSI
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHH
VVFGLIAVAGAKIWVDNRVDFSDNRNLIVAAITLIIGTGDFTLKFGDFALGGIGTATFGA
HHHHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCEECCCCCHHHHHH
IGLYALLNLRRGR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]