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The map label for this gene is tolC [C]

Identifier: 120608753

GI number: 120608753

Start: 46334

End: 47749

Strand: Reverse

Name: tolC [C]

Synonym: Aave_0040

Alternate gene names: 120608753

Gene position: 47749-46334 (Counterclockwise)

Preceding gene: 120608756

Following gene: 120608752

Centisome position: 0.89

GC content: 76.69

Gene sequence:

>1416_bases
ATGCGTTCCCATCCCCCTTCCCTTTCCCTGCGCAGCGGCACCGCGCTGCGGATCGCGGCCGGACTCCTGGCCTGCGGCGG
CGCCTGGCTGGCCGGGCCGCACCCCGCCCAGGCCCAGGCCCAGGCCCAGGCCCAGGCCCAGGCCCAGGCCACGGCGGCCA
TGCCCGCCCCCTCCCGGCCCGTCCCCGCGCCCGCCATGGCAGTTGCCCCGCGCGGCACCGGCTGGACGCTGTCCCAGGCC
CTGGCCGCCGCCCGCGACAACAGCGAAGTCCACCAGGCCCGGCAGGAACTGGCCGGCGCGCGCGCCGACGTGCTCAGCGC
CGACCACGCGCCCCTGCCCTCCCTGACCACCAAGGCCGGCTCCATCGACCTGCAGCACGGCCCCGGACCGGGCAACGTGT
TCACGCGCAAGCGCATCGACAAGTCCGTCGGCATCGACTGGACCTGGGAGCGCGGCGACAAGCGCGCGCTGCGCAAGAAG
GCGGCCGAGAGCATGGCCAACGCCGCGGAAGCCGACGTGGAAGACACGCAGGTCCAGCAGCTGCAGGCGGCCCTGGGGGC
CTACTACGACCTGCTGGCCGCGCAGGACCGCCTCGCCGAGGTCGCCGCCATCGAGCGCAGCCTGGCCGACGTGGCCGGCA
TGGCCGACCGCCGCGTGAAGGCGGGCGATCTCTCGGTGCAGGACGCCTCGCGCACCCGCATCGAGGCCGAGCGCGCCCGG
GCCGACACCCGCGCGGCCGAACAGGCCCGCGACGACGCCGCCCTGGCACTGGCCCAGGTCACGGGCAGCACCGGCAGCCG
CCTGCAGGCCGTGGACACGCCCTGGCCCCCCCTGGCCGGCGACCCGCCCGCCACCGACGCCGACCTGGCCGCCTGGGCCG
AAACCCGCGCCGACGTGCGGGCCGCCCTGGCGCGCGCGCAGGCGGCCCAGGCCGCGCTGGACGGTGCCAACGCGCTGCGC
AAGTCCGACTGGACGGTGGGCGCCTCCATCGACCATTTCCCCGGCACTTCGACCCGCCAGGTCGAACTGCGCGTGCAGAT
CCCGCTGCAGTGGGGCTACCAGTACCAGGGCGAGATCGGCCGCGCCCAGGCCGACTACGCCAAGGCGCAGGACGCGCTGG
ACAACACGCGCCGGCTCGCCCTGCTGGACCTGCAGCGCCTGCGCCAGGCACAGGAGAGCGCCGCCCGCCGCGCGGCCGAC
TACGACCAGGGCGTGCTGCCCCGCGCACGCCAGGTGGCCGACAGCGCCGAGCTGGCCTACCGCAAGGGCGCCATCGCCCT
CACCGACCTGCTGGACGCCCAGCGCACCCTGCGCGCCACGCTGCTGGACGCGCTGGCCGCCCGCGCCGACTACGCCAAGG
CGCGCGGCGCCTGGCTGCTGCGCACCCGCCCGCAGTTGCTCACCGGCACGCCCTGA

Upstream 100 bases:

>100_bases
CCAGCCGCACCGTGGCCCACAAGCCGCATTGTGTCGTGCCCGGGGCCCGGCGGCACGCCAGGTCAGGCCGTGGTCAGGCT
CGCACGCCGATAAACACGGC

Downstream 100 bases:

>100_bases
CCCCGGCCTGAACGCCGCGCCACAGCACTGCCTTCCCGCCTTCCACCGCATTCCTTTCCGGACCTCCCGACCATGATGGC
TCCCCTTCTCTCCCTTCCCG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MRSHPPSLSLRSGTALRIAAGLLACGGAWLAGPHPAQAQAQAQAQAQAQATAAMPAPSRPVPAPAMAVAPRGTGWTLSQA
LAAARDNSEVHQARQELAGARADVLSADHAPLPSLTTKAGSIDLQHGPGPGNVFTRKRIDKSVGIDWTWERGDKRALRKK
AAESMANAAEADVEDTQVQQLQAALGAYYDLLAAQDRLAEVAAIERSLADVAGMADRRVKAGDLSVQDASRTRIEAERAR
ADTRAAEQARDDAALALAQVTGSTGSRLQAVDTPWPPLAGDPPATDADLAAWAETRADVRAALARAQAAQAALDGANALR
KSDWTVGASIDHFPGTSTRQVELRVQIPLQWGYQYQGEIGRAQADYAKAQDALDNTRRLALLDLQRLRQAQESAARRAAD
YDQGVLPRARQVADSAELAYRKGAIALTDLLDAQRTLRATLLDALAARADYAKARGAWLLRTRPQLLTGTP

Sequences:

>Translated_471_residues
MRSHPPSLSLRSGTALRIAAGLLACGGAWLAGPHPAQAQAQAQAQAQAQATAAMPAPSRPVPAPAMAVAPRGTGWTLSQA
LAAARDNSEVHQARQELAGARADVLSADHAPLPSLTTKAGSIDLQHGPGPGNVFTRKRIDKSVGIDWTWERGDKRALRKK
AAESMANAAEADVEDTQVQQLQAALGAYYDLLAAQDRLAEVAAIERSLADVAGMADRRVKAGDLSVQDASRTRIEAERAR
ADTRAAEQARDDAALALAQVTGSTGSRLQAVDTPWPPLAGDPPATDADLAAWAETRADVRAALARAQAAQAALDGANALR
KSDWTVGASIDHFPGTSTRQVELRVQIPLQWGYQYQGEIGRAQADYAKAQDALDNTRRLALLDLQRLRQAQESAARRAAD
YDQGVLPRARQVADSAELAYRKGAIALTDLLDAQRTLRATLLDALAARADYAKARGAWLLRTRPQLLTGTP
>Mature_471_residues
MRSHPPSLSLRSGTALRIAAGLLACGGAWLAGPHPAQAQAQAQAQAQAQATAAMPAPSRPVPAPAMAVAPRGTGWTLSQA
LAAARDNSEVHQARQELAGARADVLSADHAPLPSLTTKAGSIDLQHGPGPGNVFTRKRIDKSVGIDWTWERGDKRALRKK
AAESMANAAEADVEDTQVQQLQAALGAYYDLLAAQDRLAEVAAIERSLADVAGMADRRVKAGDLSVQDASRTRIEAERAR
ADTRAAEQARDDAALALAQVTGSTGSRLQAVDTPWPPLAGDPPATDADLAAWAETRADVRAALARAQAAQAALDGANALR
KSDWTVGASIDHFPGTSTRQVELRVQIPLQWGYQYQGEIGRAQADYAKAQDALDNTRRLALLDLQRLRQAQESAARRAAD
YDQGVLPRARQVADSAELAYRKGAIALTDLLDAQRTLRATLLDALAARADYAKARGAWLLRTRPQLLTGTP

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49942; Mature: 49942

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHPPSLSLRSGTALRIAAGLLACGGAWLAGPHPAQAQAQAQAQAQAQATAAMPAPSRP
CCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
VPAPAMAVAPRGTGWTLSQALAAARDNSEVHQARQELAGARADVLSADHAPLPSLTTKAG
CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCC
SIDLQHGPGPGNVFTRKRIDKSVGIDWTWERGDKRALRKKAAESMANAAEADVEDTQVQQ
CEEECCCCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LQAALGAYYDLLAAQDRLAEVAAIERSLADVAGMADRRVKAGDLSVQDASRTRIEAERAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ADTRAAEQARDDAALALAQVTGSTGSRLQAVDTPWPPLAGDPPATDADLAAWAETRADVR
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALARAQAAQAALDGANALRKSDWTVGASIDHFPGTSTRQVELRVQIPLQWGYQYQGEIG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEEHEECCEECCCCC
RAQADYAKAQDALDNTRRLALLDLQRLRQAQESAARRAADYDQGVLPRARQVADSAELAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RKGAIALTDLLDAQRTLRATLLDALAARADYAKARGAWLLRTRPQLLTGTP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MRSHPPSLSLRSGTALRIAAGLLACGGAWLAGPHPAQAQAQAQAQAQAQATAAMPAPSRP
CCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
VPAPAMAVAPRGTGWTLSQALAAARDNSEVHQARQELAGARADVLSADHAPLPSLTTKAG
CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCC
SIDLQHGPGPGNVFTRKRIDKSVGIDWTWERGDKRALRKKAAESMANAAEADVEDTQVQQ
CEEECCCCCCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LQAALGAYYDLLAAQDRLAEVAAIERSLADVAGMADRRVKAGDLSVQDASRTRIEAERAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ADTRAAEQARDDAALALAQVTGSTGSRLQAVDTPWPPLAGDPPATDADLAAWAETRADVR
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AALARAQAAQAALDGANALRKSDWTVGASIDHFPGTSTRQVELRVQIPLQWGYQYQGEIG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEEHEECCEECCCCC
RAQADYAKAQDALDNTRRLALLDLQRLRQAQESAARRAADYDQGVLPRARQVADSAELAY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RKGAIALTDLLDAQRTLRATLLDALAARADYAKARGAWLLRTRPQLLTGTP
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA