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The map label for this gene is fabA [H]

Identifier: 120599192

GI number: 120599192

Start: 2753544

End: 2754059

Strand: Direct

Name: fabA [H]

Synonym: Sputw3181_2388

Alternate gene names: 120599192

Gene position: 2753544-2754059 (Clockwise)

Preceding gene: 120599191

Following gene: 120599198

Centisome position: 58.48

GC content: 42.25

Gene sequence:

>516_bases
ATGAATAAAGCAAACAGTTTCAATAAAGAAGAACTCATCGCCTGTGGCCATGGGAAATTATTTGGTCCAAACTCCCCTCG
CCTTCCTGTTGATAATATGCTGATGATCGATAGAATCGTCACTATCAATGATAATGGTGGCGAGTTTGGAAAAGGTGAAA
TTGTCGCTGAACTCGATATTAATCCAGAATTATGGTTTTTTGACTGTCATTTTATTAGCGATCCCGTTATGCCTGGTTGT
TTAGGCCTTGATGCCATGTGGCAATTAGTAGGGTTCTATTTAGGCTGGGAAGGTGCTGAAGGTAAAGGTCGTGCACTGGG
CGTTGGTGAAGTGAAGTTTACTGGTCAAGTGCTACCCGGTGCGAAAAAGGTTACCTATAAACTGAATATCAAACGCACAA
TCCACCGAAAACTCGTCATGGGAATTGCCGATGCAATTCTTGAAGTTGATGGTCGTCAAATCTACAGCGCAACCGATCTC
AAAGTCGGTGTATTTAGTGATACATCAACCTTCTAA

Upstream 100 bases:

>100_bases
CAAAATTGGGATTATTTCGTCGTTAATTAGCTGATCGGAGTTGTTTAGCTTACACGTGTTCGCTAATCTTGGCGGTTCTT
ATTGCTGGAGTAGTAAAATA

Downstream 100 bases:

>100_bases
TTATCTTTTGCTACATTTTTTATAGATACAAAAATGCCCTCATCTGAGGGCAATGTGCTGCATTACTTCGTTTGTTCTGG
GCTATTTAATTAACGAGCTA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDINPELWFFDCHFISDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF

Sequences:

>Translated_171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDINPELWFFDCHFISDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF
>Mature_171_residues
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDINPELWFFDCHFISDPVMPGC
LGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDL
KVGVFSDTSTF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=171, Percent_Identity=67.8362573099415, Blast_Score=252, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 18766; Mature: 18766

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDI
CCCCCCCCCCCEEEECCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPELWFFDCHFISDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
CEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIVTINDNGGEFGKGEIVAELDI
CCCCCCCCCCCEEEECCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCEEEEEEC
NPELWFFDCHFISDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPG
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCEEEEECEECCC
AKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
CEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA