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The map label for this gene is nhaB

Identifier: 120599147

GI number: 120599147

Start: 2699442

End: 2701028

Strand: Direct

Name: nhaB

Synonym: Sputw3181_2343

Alternate gene names: 120599147

Gene position: 2699442-2701028 (Clockwise)

Preceding gene: 120599145

Following gene: 120599148

Centisome position: 57.33

GC content: 41.4

Gene sequence:

>1587_bases
ATGCCGTTGACAATGAGTCAGGCGTTTATTGGAAACTTCCTAGGGAATTCTCCTAAGTGGTACAAAATCGCGATACTGTC
TTTTTTAATCATTAATCCAATACTCTTTTTCTATGTCAGTCCTTTTGTGGCTGGTTGGGTATTAGTACTTGAGTTTATTT
TTACCTTGGCCATGGCATTAAAATGCTATCCATTACAACCCGGTGGTTTACTGGCCATTGAGGCTGTGGCTATCGGTATG
ACTTCTGCAAACCAAGTGCTGCATGAAATAGAAGCAAACCTTGAAGTGTTATTACTACTGGTCTTTATGGTTGCTGGTAT
TTATTTCATGAAGCAATTGCTGTTGTTTGCTTTTACCAAGATTATTACCAAAGTACGCTCCAAAATTTTAGTCTCATTAA
TGTTCTGTCTAACCTCTGCATTTCTATCTGCGTTTTTAGATGCCTTAACCGTTATTGCGGTTATCATTGCCGTTGCAGTG
GGTTTTTACGCGATTTACCACAAGGTGGCATCCGGTAAAGATTTCTCTGCTGTGCATGACCATACCTCAGAAAGTAATAC
TCAATTAAATAACAGTGAGCTCGAGTCATTCCGAGGATTTCTACGTAATTTATTAATGCATGCAGGTGTTGGTACCGCCT
TAGGTGGCGTGTGTACAATGGTTGGTGAACCACAAAACTTAATTATCGCCGCCCAAGCTAACTGGCAGTTTGGTGAATTC
GTTGTTCGCATGTCTCCTGTGACAGTACCAGTACTGATCGCAGGTATTCTGACTTGCCTACTCGTGGAGAAATTCCGTAT
TTTTGGTTATGGTGCCAAACTCCCTGATGCAGTTCATAAAATTCTTTGTGATTATGCTGCCCATGAAGATGCACACCGTA
CCAATAAAGATAAGATGAAGCTTGTCATTCAAGTATTAGTAGGTGTGTGGTTAATTGCAGGCTTAGCGTTGCATTTAGCT
TCTGTTGGTTTAGTGGGTTTATCGGTGATTATTTTAACCACAGCTTTCAACGGTATCACCGATGAGCATGCTCTGGGTAA
AGCCTTTGAAGAAGCACTTCCATTCACTGCACTATTGGCAGTATTTTTTGCTGTAGTTGCCGTCATTATTGATCAACATT
TATTTGCGCCAGTCATCCAATGGGCATTGAGTTATGAAGGAAATACCCAATTAGTTATTTTCTATATTGCTAACGGTTTA
CTTTCAATGGTGAGCGATAACGTGTTTGTGGGTACGGTTTATATCAACGAAGTCAAAGCAGCCTTGATTGATGGTCAAAT
TACCCGTGATCAATTCGATCTGCTCGCTGTTGCAATTAACACTGGTACTAACCTACCTTCTGTAGCGACACCCAATGGAC
AAGCCGCGTTCTTGTTCTTACTCACCTCAGCATTAGCGCCACTGATTCGGTTGTCTTATGGCAGAATGGTGTGGATGGCT
CTACCCTATACAATCGTACTGTCAGTTGTAGGTGTATTAGCTATTGAGACAGGCTTCTTAGAGCAAGCAACGCAATACTT
CTATGACTCGCATATGATTATTCATCACAGTGCTAAAGACGTTATCGCCCCCCTGACAAGTCACTAA

Upstream 100 bases:

>100_bases
CATTCTCTTTCAGCTAGACTGTTTTCCCAAACACGAGTAAACACAAATCACACGTGCCAATTTTTCAACCTTTTTCAACA
TAATTAGAAGAGAGGATGCT

Downstream 100 bases:

>100_bases
CTCAGGTCTAAGCATTGACTGAACTTTATTAAATCAGTAGAGTCGAAAAAAACGCCCCAATGATTGAGGGGCGTTTTTCG
TTGATATGGAGCTCACATTT

Product: sodium/proton antiporter

Products: Na (I) [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Sodium/proton antiporter nhaB [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MPLTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSANQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKIITKVRSKILVSLMFCLTSAFLSAFLDALTVIAVIIAVAV
GFYAIYHKVASGKDFSAVHDHTSESNTQLNNSELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEF
VVRMSPVTVPVLIAGILTCLLVEKFRIFGYGAKLPDAVHKILCDYAAHEDAHRTNKDKMKLVIQVLVGVWLIAGLALHLA
SVGLVGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQHLFAPVIQWALSYEGNTQLVIFYIANGL
LSMVSDNVFVGTVYINEVKAALIDGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMA
LPYTIVLSVVGVLAIETGFLEQATQYFYDSHMIIHHSAKDVIAPLTSH

Sequences:

>Translated_528_residues
MPLTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGM
TSANQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKIITKVRSKILVSLMFCLTSAFLSAFLDALTVIAVIIAVAV
GFYAIYHKVASGKDFSAVHDHTSESNTQLNNSELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEF
VVRMSPVTVPVLIAGILTCLLVEKFRIFGYGAKLPDAVHKILCDYAAHEDAHRTNKDKMKLVIQVLVGVWLIAGLALHLA
SVGLVGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQHLFAPVIQWALSYEGNTQLVIFYIANGL
LSMVSDNVFVGTVYINEVKAALIDGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMA
LPYTIVLSVVGVLAIETGFLEQATQYFYDSHMIIHHSAKDVIAPLTSH
>Mature_527_residues
PLTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIEAVAIGMT
SANQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKIITKVRSKILVSLMFCLTSAFLSAFLDALTVIAVIIAVAVG
FYAIYHKVASGKDFSAVHDHTSESNTQLNNSELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEFV
VRMSPVTVPVLIAGILTCLLVEKFRIFGYGAKLPDAVHKILCDYAAHEDAHRTNKDKMKLVIQVLVGVWLIAGLALHLAS
VGLVGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQHLFAPVIQWALSYEGNTQLVIFYIANGLL
SMVSDNVFVGTVYINEVKAALIDGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMAL
PYTIVLSVVGVLAIETGFLEQATQYFYDSHMIIHHSAKDVIAPLTSH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG3067

COG function: function code P; Na+/H+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaB Na(+)/H(+) (TC 2.A.34) antiporter family [H]

Homologues:

Organism=Escherichia coli, GI1787435, Length=486, Percent_Identity=68.1069958847737, Blast_Score=655, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004671 [H]

Pfam domain/function: PF06450 NhaB [H]

EC number: NA

Molecular weight: Translated: 57495; Mature: 57364

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCC
>Mature Secondary Structure 
PLTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMAL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KCYPLQPGGLLAIEAVAIGMTSANQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTK
HCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITKVRSKILVSLMFCLTSAFLSAFLDALTVIAVIIAVAVGFYAIYHKVASGKDFSAVHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
HTSESNTQLNNSELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
VVRMSPVTVPVLIAGILTCLLVEKFRIFGYGAKLPDAVHKILCDYAAHEDAHRTNKDKMK
HHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHH
LVIQVLVGVWLIAGLALHLASVGLVGLSVIILTTAFNGITDEHALGKAFEEALPFTALLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHH
VFFAVVAVIIDQHLFAPVIQWALSYEGNTQLVIFYIANGLLSMVSDNVFVGTVYINEVKA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEHHHHHH
ALIDGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMA
HHHCCCCCHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYTIVLSVVGVLAIETGFLEQATQYFYDSHMIIHHSAKDVIAPLTSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3 Proton [Periplasm]; Na (I) [Cytoplasm] [C]

Specific reaction: 3 Proton [Periplasm] + 2 Na (I) [Cytoplasm] = 2 Na (I) [Periplasm] + 3 Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA