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The map label for this gene is dsbB [H]

Identifier: 120599148

GI number: 120599148

Start: 2701088

End: 2701654

Strand: Direct

Name: dsbB [H]

Synonym: Sputw3181_2344

Alternate gene names: 120599148

Gene position: 2701088-2701654 (Clockwise)

Preceding gene: 120599147

Following gene: 120599149

Centisome position: 57.37

GC content: 43.74

Gene sequence:

>567_bases
ATGATTGAGGGGCGTTTTTCGTTGATATGGAGCTCACATTTGACAGCACTTACTCGCTTTGCCCATTCTCGCAGTTCTTG
GTTCCTTCTCACGGGCACCGCTATTGGCTTAGAAGCCGCTGCACTGTATTTTCAGTATGTGATGAAACTCGATCCCTGTG
TCATGTGTATCTATCAAAGATTAGCTGTATTTGGCATTTTGGTCGCAGGTTTGATAGGAATGACAGCCCCTAAGTATCGT
CTGATACGAATATTAGGAGCGAGCTGTTGGGCCGTGAGTGCCACTTGGGGATTAAAATTAGCTTTAGCGCTAGTGAATAT
GCAAAATAACCCTTCCCCTTTTGCTACTTGCTCATTTTTACCCGAATTTCCAACTTGGATGCCATTACACGAATGGTTTC
CTGCGGTAATGTTACCAACAGGCATGTGTACCGATTTACCATGGCGTTTTATGGATGTCACCATGGCAGAATGGATGGTT
GTCGTCTTTAGCACTTTCCTCGTGATTTGGTTACTGTTTATCGTGCCAATTCTAAGTGGCTCCACTAAACCTTCTCTTTA
TAAATAA

Upstream 100 bases:

>100_bases
ACAGTGCTAAAGACGTTATCGCCCCCCTGACAAGTCACTAACTCAGGTCTAAGCATTGACTGAACTTTATTAAATCAGTA
GAGTCGAAAAAAACGCCCCA

Downstream 100 bases:

>100_bases
CGGTTTCCGTTGGCAGGCAAATTTGCCTGCCTTCCAATAAAATTTTCTTCTTAAATCAACCATTATTACCTTCTTTATCC
CACTGATTTTGATATAGACC

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MIEGRFSLIWSSHLTALTRFAHSRSSWFLLTGTAIGLEAAALYFQYVMKLDPCVMCIYQRLAVFGILVAGLIGMTAPKYR
LIRILGASCWAVSATWGLKLALALVNMQNNPSPFATCSFLPEFPTWMPLHEWFPAVMLPTGMCTDLPWRFMDVTMAEWMV
VVFSTFLVIWLLFIVPILSGSTKPSLYK

Sequences:

>Translated_188_residues
MIEGRFSLIWSSHLTALTRFAHSRSSWFLLTGTAIGLEAAALYFQYVMKLDPCVMCIYQRLAVFGILVAGLIGMTAPKYR
LIRILGASCWAVSATWGLKLALALVNMQNNPSPFATCSFLPEFPTWMPLHEWFPAVMLPTGMCTDLPWRFMDVTMAEWMV
VVFSTFLVIWLLFIVPILSGSTKPSLYK
>Mature_188_residues
MIEGRFSLIWSSHLTALTRFAHSRSSWFLLTGTAIGLEAAALYFQYVMKLDPCVMCIYQRLAVFGILVAGLIGMTAPKYR
LIRILGASCWAVSATWGLKLALALVNMQNNPSPFATCSFLPEFPTWMPLHEWFPAVMLPTGMCTDLPWRFMDVTMAEWMV
VVFSTFLVIWLLFIVPILSGSTKPSLYK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

Organism=Escherichia coli, GI1787433, Length=174, Percent_Identity=39.6551724137931, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 21199; Mature: 21199

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGRFSLIWSSHLTALTRFAHSRSSWFLLTGTAIGLEAAALYFQYVMKLDPCVMCIYQR
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHH
LAVFGILVAGLIGMTAPKYRLIRILGASCWAVSATWGLKLALALVNMQNNPSPFATCSFL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
PEFPTWMPLHEWFPAVMLPTGMCTDLPWRFMDVTMAEWMVVVFSTFLVIWLLFIVPILSG
CCCCCCCCHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STKPSLYK
CCCCCCCC
>Mature Secondary Structure
MIEGRFSLIWSSHLTALTRFAHSRSSWFLLTGTAIGLEAAALYFQYVMKLDPCVMCIYQR
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHH
LAVFGILVAGLIGMTAPKYRLIRILGASCWAVSATWGLKLALALVNMQNNPSPFATCSFL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
PEFPTWMPLHEWFPAVMLPTGMCTDLPWRFMDVTMAEWMVVVFSTFLVIWLLFIVPILSG
CCCCCCCCHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STKPSLYK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA