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The map label for this gene is fadE

Identifier: 120599038

GI number: 120599038

Start: 2582364

End: 2584811

Strand: Direct

Name: fadE

Synonym: Sputw3181_2234

Alternate gene names: 120599038

Gene position: 2582364-2584811 (Clockwise)

Preceding gene: 120599036

Following gene: 120599040

Centisome position: 54.85

GC content: 47.88

Gene sequence:

>2448_bases
GTGACTACCCTACTTTGGATCATCGCTATGATCTTAGTGTTAGGAGCCCTAGCTTACCTTCGGGTATCTTTGCTCACTGC
CACTATCGCAGCCGCTGTTGTGATGACAGCAGGATGGACACTCGATGTTGTCGGCCCTATCTCTTGGATCGTTTTCCTTG
TGATTGCCTTGCCACTTAACATCAGTGCATTTAGACAAAATGTAATCAGTCGCCCACTGATGAAGATATATCGTGGCATC
ATGCCTGAAATGTCTTCTACCGAAAAAGAAGCGATTGAAGCCGGTACCACTTGGTGGGAAGCCGATCTGTTTTCAGGTAA
CCCGAACTGGAAAAAACTCCATAACTACCCAGTTGCGCGTTTAAGTGCAGATGAGCAAGCCTTCCTCGATGGCCCAGTAG
AAGAAGTGTGCCGCATGGTAAACCAACACCAGGTATCACACCAACTCGCTGACTTACCTGCAGAAGTATGGCAATACCTC
AAAGATCATGGCTTCTTTGCTATGATCATCAAGAAAAAATACGGCGGTTTAGAGTATTCAGCCTATGCACAATCCCGTGT
GTTGCAAAAACTAGCAGGCGTCAGCAGTGAGTTAGCTTCAACTGTTGGTGTACCGAACTCTTTAGGCCCTGGTGAACTAT
TGCAACATTACGGCACGCCAGAGCAACAAAACCATTATTTACCGCGTTTAGCCAAAGGGTTAGAAGTCCCTTGTTTCGCT
CTGACCAGCCCAGAAGCCGGTAGCGATGCAGGCTCGATTCCTGATTTTGGTATCGTGTGTAAAGGTCAATGGGAAGGCGA
AGAAGTTCTGGGGATGAAGTTAACCTGGAACAAACGCTATATCACCTTAGCACCGGTTGCCACTGTATTAGGTTTAGCCT
TCAAACTGCGCGATCCTGATCATCTACTTGGTGATAAAGAAGAGCTCGGCATTACCTGCGCACTGATCCCAACCGATGTT
GAAGGTGTTGAAACGGGTCGTCGTCACTTCCCGCTCAACTGTATGTTCCAAAACGGTCCGACTCGCGGCAACGAAGTATT
CGTGCCATTAAGCTTCATCATTGGCGGCCCGAAAATGGCTGGTCAAGGCTGGCGCATGCTGGTGGAATGTTTATCAGTGG
GTCGTGGTATCACGCTGCCATCAAACTCAGCGGGTGGCGTGAAAACCGCAGCACTGGCAACGGGTGCCTATGCGCGCATT
CGTCGTCAATTCAAACTGCCCATTGGTAAGTTAGAAGGCATTGAAGAGCCAATGGCTCGCATCGGTGGCAACGCCTACCT
AATGGATGCGGTCACTTCGCTAACAACGACAGGTATTGATTTAGGAGAAAAACCATCGGTTATCTCTGCAATAGTGAAAT
ACCACTTAACCGATAGAATGCAGAAATGCATCATCGATGCCATGGACATTCATGGCGGTAAAGGCGTATGTCTTGGCCCG
AATAACTATTTAGGCCGTGGTTACCAAGCTGCGCCTATCGCGATTACTGTTGAAGGTGCAAACATCCTCACCCGTTCGAT
GATCATCTACGGCCAAGGCGCGATCCGTTGCCATCCGTACGTGCTTGCCGAAATGGAATCCGCGTTTGATACCCAGTCGG
GTCAAGGTTTAGCCAATTTCGATGCGGCAATTTTCGGTCATATTGGTTTTGCGACCAGTAATTTTGTTCGTAGCTTCTGG
TTAGGTCTGACATCGAGCCGTTTCTCAAACGCGCCTTACTCAGATAAAACCAAGCGTTATTATCAACATATGAATCGTTT
CAGTGCCAACCTTGCCCTACTCTCTGACTTAGCCATGGCAACGTTGGGTGGTAACCTTAAACGTAAAGAACGTATCTCTG
CCCGTTTAGGTGACTTATTAAGTCAACTGTATCTGGCATCAGCCACACTGAAACGCTATGAAGATGAAGGCCGTCAAACC
GACGACTTGCCATTAGTACAATGGGCCGTTGAAGATGCACTATACAAGCTACAAGCATCTTTAGACGATTTACTGGATAA
CTTCCCTATGGGTCTTGGCGGCGTATTACGTGTGGTGATGTTCCCATTCGGTCGTCCACTGAAACGCCCAAGCGATGTGT
TAGATCATAAAGTCGCTAAGATCATGCAAACACCCTGTGAAAGTCGTGACCGTTTAGGTAAAGGCCAGTTCTGGACTAAC
TCGGAGCACAATGCTGTAGGTATTCAAGAGCAAACGCTTAAGGATATTCTGGCTGCCGAACCTTTATTTGACAAAGTCTG
TAAAGCCAGTGGTAAACGTCTACCCTTTATGTGGTTAGATAAAGTGGCCGCTGAAGGCAAAGCCTTAGGGGTATTGAGCG
ATAGCGAAATACAACTGTTGGAAAGAGCCGAGATTGGCCGCATGAAGTCAATCAATGTGGATGACTTTGACCCAGCAGAA
CTGCGTCCAGAAGTAGTTTCTGCTACTTCACAAGAGCGCGCAGCCTAA

Upstream 100 bases:

>100_bases
ATGCGACACAGGTCTGACCACAAACTATAATTGTGATCGCCATCAATAAAACTCGCTATGACCTGTGGTTGGCACTCGGT
CATACTTAAGGAGAATTACA

Downstream 100 bases:

>100_bases
TAACCACATAGGATTGGTTATTACACAAAGAAAGGAGGCTGTATAAGCCTCCTTTCTTTTGTTCATCACTAAACGCTAAC
GCTTCACTTTGGTCAAGACT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIVFLVIALPLNISAFRQNVISRPLMKIYRGI
MPEMSSTEKEAIEAGTTWWEADLFSGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCIIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTQSGQGLANFDAAIFGHIGFATSNFVRSFW
LGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRQT
DDLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRVVMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEIQLLERAEIGRMKSINVDDFDPAE
LRPEVVSATSQERAA

Sequences:

>Translated_815_residues
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIVFLVIALPLNISAFRQNVISRPLMKIYRGI
MPEMSSTEKEAIEAGTTWWEADLFSGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCIIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTQSGQGLANFDAAIFGHIGFATSNFVRSFW
LGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRQT
DDLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRVVMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEIQLLERAEIGRMKSINVDDFDPAE
LRPEVVSATSQERAA
>Mature_814_residues
TTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIVFLVIALPLNISAFRQNVISRPLMKIYRGIM
PEMSSTEKEAIEAGTTWWEADLFSGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLK
DHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFAL
TSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDVE
GVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIR
RQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCIIDAMDIHGGKGVCLGPN
NYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTQSGQGLANFDAAIFGHIGFATSNFVRSFWL
GLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRQTD
DLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRVVMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTNS
EHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEIQLLERAEIGRMKSINVDDFDPAEL
RPEVVSATSQERAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=553, Percent_Identity=26.4014466546112, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI4557235, Length=410, Percent_Identity=25.1219512195122, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4557233, Length=414, Percent_Identity=26.5700483091787, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI76496475, Length=389, Percent_Identity=25.4498714652956, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI87081702, Length=816, Percent_Identity=65.5637254901961, Blast_Score=1103, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=320, Percent_Identity=25.3125, Blast_Score=74, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=269, Percent_Identity=26.0223048327138, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=339, Percent_Identity=24.4837758112094, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363737, Length=445, Percent_Identity=25.1685393258427, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646207, Length=329, Percent_Identity=26.4437689969605, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355753, Length=323, Percent_Identity=24.1486068111455, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89301; Mature: 89170

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIVFLVIALPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC
ISAFRQNVISRPLMKIYRGIMPEMSSTEKEAIEAGTTWWEADLFSGNPNWKKLHNYPVAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCCCE
LSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLKDHGFFAMIIKKKYGGLEYS
ECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDKEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGPKMA
HHCCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHEECCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCIIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTQSGQGLANF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHHCCCCCCCCHHH
DAAIFGHIGFATSNFVRSFWLGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRQTDDLPLVQWAVEDALYKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGGVLRVVMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEIQLL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHH
ERAEIGRMKSINVDDFDPAELRPEVVSATSQERAA
HHHHCCCCCCCCCCCCCHHHCCHHHHHCCHHHCCC
>Mature Secondary Structure 
TTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIVFLVIALPLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC
ISAFRQNVISRPLMKIYRGIMPEMSSTEKEAIEAGTTWWEADLFSGNPNWKKLHNYPVAR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHCCCCCCE
LSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLKDHGFFAMIIKKKYGGLEYS
ECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMKLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDKEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGNEVFVPLSFIIGGPKMA
HHCCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHEECCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCIIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTQSGQGLANF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHHCCCCCCCCHHH
DAAIFGHIGFATSNFVRSFWLGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRQTDDLPLVQWAVEDALYKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGGVLRVVMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEIQLL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCCHHHHH
ERAEIGRMKSINVDDFDPAELRPEVVSATSQERAA
HHHHCCCCCCCCCCCCCHHHCCHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]