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The map label for this gene is hlyB [H]

Identifier: 120598850

GI number: 120598850

Start: 2351876

End: 2353504

Strand: Direct

Name: hlyB [H]

Synonym: Sputw3181_2040

Alternate gene names: 120598850

Gene position: 2351876-2353504 (Clockwise)

Preceding gene: 120598849

Following gene: 120598852

Centisome position: 49.95

GC content: 44.44

Gene sequence:

>1629_bases
ATGAACGTTATAAATCGCTTGTACTCAGGCTTCGCTATGCTGCTGTTGATTATGCTTGGAATCACACTTTTTGGTCTGTT
TAAAATCAGCATAGCGGACCAGAATTTAACTCAACTCTCAGAACAGACTGCGGTTGAACAGCGTCAGGCCATTAACTTCC
GCGGCAGTGTGCATGATAGAGCAATTTCGATTCGTGACGCAGTTTTAGTCAAAGATACCAGCGCATCTCAGATTCACCAA
AATGACATAACCCGATTAAATGGCTTTTACCAGCAATCCGCCGCTACGCTGGATAGTATGTATAGCAAGATAAAACATAC
CCCTGAAGAAGAAAACTTACTACGCCAAATCAAGGAAATAGAAAGCTCCACCTTAGCTGTCACCAAAAACATTCTGGATA
TGATTAACAGCGGACGCCAGCAAGAAGCCACAGACTACTTATTAACCACAGTATCTCCTGCTTACAGCGAATGGCTGAAA
CGCATCAATAAGCTGATCGATTTTCAGGAAGAAGCCATACAACATCAGGTGGCGTCGGCCCGTGAACAAACAAATAGCTT
TCAGCGGATCATGCTTTTAGTCACGGCCATTGCAATAGTCATTGGTTGTGTCGTCGCTGTTAGTACAGTGAATCGATTAA
AAAGAATGGTCGGTGGTGAGCCCGAATATGCAGCGTCGGTCATTAAAAAAATTGCCTCTGGTGATTTAACAGTTCAGGTG
AAATCTCACACTGCAGAAAGTATTTTAAGTGCAGTAAAAGATCTGACAGAACATATGTCGGGTATCACCAAAAACTCAAT
ACGAGCAGCTAACGAATTACTTACGGCTTCCAAACAGCTGTTGGAGACAGCGCAATACAACGAAGATTTGATTGGCAACC
AAAAACTGGCCACTGAACAAGGTGCTACAGCCATTAACCAAATGTCATCCACTGTAGCTGAGGTTGCCAACCATACCAGC
GATGCCGCAGGTCTTGCTCAAACTGCAATCAACGAATTCAACGCCGGTCAGGCTGAAGTCAGTAAAACTCAATCCAGTAT
CAATGCACTGGCAGATAAAGTGAGTGACGCTGCAGAGGTAATCAATCATTTATCGGAAGATAGCCGTCAGATAGGCTCAG
TGCTTGAAGTGATCCAGGGCATAGCTGAACAAACCAATTTATTGGCATTAAACGCAGCTATTGAAGCGGCCAGAGCTGGC
GAACAAGGCCGTGGTTTTGCAGTAGTTGCCGATGAAGTGCGTAATCTAGCTCGTCGAACTCAGGATTCAACCCGTCAAAT
CCAAACTGTTATTGAGAAAATGCAGGGCAGTTCTTTAAAAGCTGTGGCAGTGATGAACGAAGGTAAAGCTCAGGCAGAAA
CCAGTGTAGAACAGGCTCAACGCGCAGGTGACTCACTGAATGCGATCAACCTGTCAGTGACAAAAATAAGCGATATGAAT
ACCCAAATCGCCACAGCAGCTGAAGAACAATCCGTGGTTGCATCCGAGATCAACCGTAATTTTAGCCAAATTACCCATTC
AGCCGTGATGGCTGAAGAGCAAGCCAGTAAGATAACTGTTGCCAGTCAGCAGCTTGAAAAACTGGCTAAAACCTTAGAGC
AAAATGTGAAGCAGTTCAAAACAGCATAA

Upstream 100 bases:

>100_bases
TAATAAATTATGTTTTCTTATGAACTAAAACTCTGGTTCTTCGTAAATAAAACGGTGCTGTCAATAAATTAGAACAGTAA
TAAAAAATAAGGTGTGATAG

Downstream 100 bases:

>100_bases
TTCAGCTGCTTTTGATCTAATGCGGTCGCAGCGTGACTTTTTTACAAGCTAACACAGGTAAGAGGCTGCATTTCGAGACA
TTCAGAGGGGATTTTTCCCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDRAISIRDAVLVKDTSASQIHQ
NDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEIESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLK
RINKLIDFQEEAIQHQVASAREQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQV
KSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQGATAINQMSSTVAEVANHTS
DAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEVINHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRNLARRTQDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMN
TQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFKTA

Sequences:

>Translated_542_residues
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDRAISIRDAVLVKDTSASQIHQ
NDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEIESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLK
RINKLIDFQEEAIQHQVASAREQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQV
KSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQGATAINQMSSTVAEVANHTS
DAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEVINHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRNLARRTQDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMN
TQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFKTA
>Mature_542_residues
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDRAISIRDAVLVKDTSASQIHQ
NDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEIESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLK
RINKLIDFQEEAIQHQVASAREQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQV
KSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQGATAINQMSSTVAEVANHTS
DAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEVINHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRNLARRTQDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMN
TQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFKTA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=32.1739130434783, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=330, Percent_Identity=31.5151515151515, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=275, Percent_Identity=34.1818181818182, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788194, Length=400, Percent_Identity=29, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789453, Length=210, Percent_Identity=30.952380952381, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58843; Mature: 58843

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AISIRDAVLVKDTSASQIHQNDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEI
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLKRINKLIDFQEEAIQHQVASA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEE
KSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHH
GATAINQMSSTVAEVANHTSDAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
INHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLARRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMN
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TA
CC
>Mature Secondary Structure
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AISIRDAVLVKDTSASQIHQNDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEI
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLKRINKLIDFQEEAIQHQVASA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEE
KSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHH
GATAINQMSSTVAEVANHTSDAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
INHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLARRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
QDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMN
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
TQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]