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The map label for this gene is lolA [H]

Identifier: 120598816

GI number: 120598816

Start: 2319854

End: 2320480

Strand: Direct

Name: lolA [H]

Synonym: Sputw3181_2002

Alternate gene names: 120598816

Gene position: 2319854-2320480 (Clockwise)

Preceding gene: 120598815

Following gene: 120598817

Centisome position: 49.27

GC content: 39.71

Gene sequence:

>627_bases
ATGAAAAACCTTTTATGCGCAGTGATGTTAACGTCACCTTTATTATATAGCACTGCTGTTTTTGCTGATGATGCGCAGCA
ACTTAGGAACACACTGGTTAACACGGCCTCACTCAAGACGGATTTTAAGCAAACCGTGACCGATGTGAACAAAAAAGTTA
TCCAAACTGGCTCTGGTATCTTAGCTCTAGCACATCCAAACCAATTTTATTGGCACTTAACCTCACCCGATGAATCACAA
ATCGTCGCTGATGGAAAAGATTTGTGGATTTACAATCCTTTTGCCGAGGAAGTGGTGATTATGGATTTTGCAGAGGCAAT
CAATGCCTCACCTATTGCATTATTAGTTCACCGAGATGACACCACTTGGTCACAGTATTCGGTGACCAAAAAGCAAGATT
GTTATGACATTCGACCTAAAGCTATTGATTCGGGCATTGTGACTGTGAGTGTGTGTTTTAAAAATTCACAACTGACTAAG
TTCAATGTACTTGATGACAAAGGAAATCTCAGCCAGTTTGATTTAAGCAATCAAAAAGTCATCACAACTGAAGACAAGGC
GTTGTTTAAGTTTGTTTTACCTGAGAATGTCGATATCGATGATCAGCGTCTTAAAACGCTTAACTAG

Upstream 100 bases:

>100_bases
CCTCCGCCCCCAAAACATTATTAATTGTGGGCTCAATGCCGACGATTAGGCCAGATGAAAGTCTGGCCATGTTAACGACT
TTTAAGCAGTAAGGATTAAG

Downstream 100 bases:

>100_bases
GTCAGAGTGTGAGTAGTCTATCATTTAATTTTGCCCCTGATTTTCGACCTCTCGCCGCTCGCATGCGGCCAAGGTCAATA
GCCGAATATATTGGTCAAGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGILALAHPNQFYWHLTSPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDTTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTK
FNVLDDKGNLSQFDLSNQKVITTEDKALFKFVLPENVDIDDQRLKTLN

Sequences:

>Translated_208_residues
MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGILALAHPNQFYWHLTSPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDTTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTK
FNVLDDKGNLSQFDLSNQKVITTEDKALFKFVLPENVDIDDQRLKTLN
>Mature_208_residues
MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGILALAHPNQFYWHLTSPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDTTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTK
FNVLDDKGNLSQFDLSNQKVITTEDKALFKFVLPENVDIDDQRLKTLN

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=204, Percent_Identity=32.843137254902, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 23353; Mature: 23353

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGI
CCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LALAHPNQFYWHLTSPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCEEEEEECCCCCCEEEECCCEEEEECCHHHHHHHEEHHHHCCCCCEEEEEECCC
TTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTKFNVLDDKGNLSQFDLSNQKV
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCEECCCCCEE
ITTEDKALFKFVLPENVDIDDQRLKTLN
EEECCCEEEEEECCCCCCCCHHHHCCCC
>Mature Secondary Structure
MKNLLCAVMLTSPLLYSTAVFADDAQQLRNTLVNTASLKTDFKQTVTDVNKKVIQTGSGI
CCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LALAHPNQFYWHLTSPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCEEEEEECCCCCCEEEECCCEEEEECCHHHHHHHEEHHHHCCCCCEEEEEECCC
TTWSQYSVTKKQDCYDIRPKAIDSGIVTVSVCFKNSQLTKFNVLDDKGNLSQFDLSNQKV
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCEECCCCCEE
ITTEDKALFKFVLPENVDIDDQRLKTLN
EEECCCEEEEEECCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA