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The map label for this gene is hlyB [H]

Identifier: 120598773

GI number: 120598773

Start: 2265348

End: 2266967

Strand: Direct

Name: hlyB [H]

Synonym: Sputw3181_1958

Alternate gene names: 120598773

Gene position: 2265348-2266967 (Clockwise)

Preceding gene: 120598772

Following gene: 120598776

Centisome position: 48.11

GC content: 43.46

Gene sequence:

>1620_bases
ATGTTAAGGACGATAAAAATCCAAACCCGCCTATTAATCGCTTTTTTGCTCATGGCATTGCTGCTGATCGGCTTAAGTGG
ATTATCAATTTCATCGATGAAAACTATCCGCGCAAATGCCAATACCGTTGAAACCAATTTATTACCTTCAATCATGAGTC
TTGGTGAGCTTAATTCAAATATGATGCGAATTAGGGTGCTCACACTCAGGTTATTAGTCAGCGAGACTCAAGAAAGCCGC
GAACAAGTTGCTAACGTTATCCGCGATCTTAAATTGGAGATTGAAAAAAATCAGGCTCAGTATGAACAACTGATCTCGAT
GGATAATGAGCGGGCGGTATACCGTGCATTTGAACAAGTCCAAAAGACCTATTATGTTGAACAAGATAAATTAATTAGTT
TTGCAACATCGGGAAAATTAGATGAAGCTAAATTGGTACTGCCGCAGCTTTATACATTGGCTGATGAGATAGTTAAAGAT
CTTAGAGATCTGGTTGCCATAAACAAAGCATCCTCCGATGACACTCGTATTGTCTCAATTACGGAATATGATAGTAATTT
TTGGTTAGTCATTGTGACAGTGATCGTTGCCAGTATCATTGCCATCGTTATTGCTTTTATGTTGTCGAATAGTATTAATC
AGCCCCTACAAGCTGCAGTCAAAACCGCAGAAATTATTGCCCATGGTGATTTAACTCAGTCGATAAGTGTCAGTGGTGAC
GATGAGTTAACTCGTCTTGTTACTGCGTTACAAATTATGCAGCGCAATTTAAGGGACGCCATTGTGCATATCGGCAGTTC
CTCTAGCCAACTAGCCTCCGCCGCAGAAGAACTCAACTCCGTCACAGAAGACTCATCCCGTGGTTTACAGCTACAAAATG
ATGAGATCCAACAAGCCGCTACAGCAATAACTGAAATGAGCACTGCTGTGGATGAAGTCGCTCGTACTGCTCAACAAGCG
TCAGATGCATCTTCTGAATCGGCCAAGCTTGCGGTAGAAGGTAAAAATCGAGTCGAGGATACAACTGCCGTTATCACCGA
AATTAACGATGAGATGACCAAAAGTACGACGGTCATTAATCAGTTGGCTGCTCAGGTTGTTTCAATTAGTAAGTTGCTGG
ATGTGATCCGCTCAGTATCAGAGCAAACTAACTTATTAGCACTCAATGCTGCCATTGAGGCGGCTCGCGCGGGTGAGGCG
GGACGTGGGTTCGCGGTTGTCGCCGACGAGGTAAGAAGCCTTGCCCATAGAACACAAGTATCTGCAGGTGAAATTGAGAC
TATGGTACGGCAAGTACAAGTTTCTGCTGAGGCTGCAGTCACCTCCATGGTCACTACAAGTGAAAAAACCAATCAAGCCC
GTATTGTTGCCGACGAAGCGACTAAAGCACTCGATCAGATCACCACGCGTATTGTTGCAATCAGTGACAGTAATCATGTG
ATCGCGAGCGCTGCTGAAGAACAATCAACCGTAGCAAGGGAAATTGATAATAATATTATGACCATTAGAGATTTAGCGGC
TCAAACGGCTGCAGGCGCTCACCAAACAAGTGCGAGTTCTGCAGAACTAACCCGTTTAGCGGTAGATTTAAATACGTTAG
TGGTTAAATTTAAAGTCTAG

Upstream 100 bases:

>100_bases
TTCCTATCTATAATTTAGAGCGCAGATGATTATCTAATCGCTATATTCCTATATTCGATTGGATGACATCATTATTTCAA
TATAGATAAGGTAATTAACT

Downstream 100 bases:

>100_bases
GTTTGGGTTATTGATGGTTAAAAAGCCCCTAATGCAGGGGCTAAAAATCACAGTTAACTTACTCTTGGATAGATGGCTTA
CCAAATACCGGCATACCTGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MLRTIKIQTRLLIAFLLMALLLIGLSGLSISSMKTIRANANTVETNLLPSIMSLGELNSNMMRIRVLTLRLLVSETQESR
EQVANVIRDLKLEIEKNQAQYEQLISMDNERAVYRAFEQVQKTYYVEQDKLISFATSGKLDEAKLVLPQLYTLADEIVKD
LRDLVAINKASSDDTRIVSITEYDSNFWLVIVTVIVASIIAIVIAFMLSNSINQPLQAAVKTAEIIAHGDLTQSISVSGD
DELTRLVTALQIMQRNLRDAIVHIGSSSSQLASAAEELNSVTEDSSRGLQLQNDEIQQAATAITEMSTAVDEVARTAQQA
SDASSESAKLAVEGKNRVEDTTAVITEINDEMTKSTTVINQLAAQVVSISKLLDVIRSVSEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAHRTQVSAGEIETMVRQVQVSAEAAVTSMVTTSEKTNQARIVADEATKALDQITTRIVAISDSNHV
IASAAEEQSTVAREIDNNIMTIRDLAAQTAAGAHQTSASSAELTRLAVDLNTLVVKFKV

Sequences:

>Translated_539_residues
MLRTIKIQTRLLIAFLLMALLLIGLSGLSISSMKTIRANANTVETNLLPSIMSLGELNSNMMRIRVLTLRLLVSETQESR
EQVANVIRDLKLEIEKNQAQYEQLISMDNERAVYRAFEQVQKTYYVEQDKLISFATSGKLDEAKLVLPQLYTLADEIVKD
LRDLVAINKASSDDTRIVSITEYDSNFWLVIVTVIVASIIAIVIAFMLSNSINQPLQAAVKTAEIIAHGDLTQSISVSGD
DELTRLVTALQIMQRNLRDAIVHIGSSSSQLASAAEELNSVTEDSSRGLQLQNDEIQQAATAITEMSTAVDEVARTAQQA
SDASSESAKLAVEGKNRVEDTTAVITEINDEMTKSTTVINQLAAQVVSISKLLDVIRSVSEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAHRTQVSAGEIETMVRQVQVSAEAAVTSMVTTSEKTNQARIVADEATKALDQITTRIVAISDSNHV
IASAAEEQSTVAREIDNNIMTIRDLAAQTAAGAHQTSASSAELTRLAVDLNTLVVKFKV
>Mature_539_residues
MLRTIKIQTRLLIAFLLMALLLIGLSGLSISSMKTIRANANTVETNLLPSIMSLGELNSNMMRIRVLTLRLLVSETQESR
EQVANVIRDLKLEIEKNQAQYEQLISMDNERAVYRAFEQVQKTYYVEQDKLISFATSGKLDEAKLVLPQLYTLADEIVKD
LRDLVAINKASSDDTRIVSITEYDSNFWLVIVTVIVASIIAIVIAFMLSNSINQPLQAAVKTAEIIAHGDLTQSISVSGD
DELTRLVTALQIMQRNLRDAIVHIGSSSSQLASAAEELNSVTEDSSRGLQLQNDEIQQAATAITEMSTAVDEVARTAQQA
SDASSESAKLAVEGKNRVEDTTAVITEINDEMTKSTTVINQLAAQVVSISKLLDVIRSVSEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAHRTQVSAGEIETMVRQVQVSAEAAVTSMVTTSEKTNQARIVADEATKALDQITTRIVAISDSNHV
IASAAEEQSTVAREIDNNIMTIRDLAAQTAAGAHQTSASSAELTRLAVDLNTLVVKFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=513, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=30.4225352112676, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788195, Length=518, Percent_Identity=27.7992277992278, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788194, Length=301, Percent_Identity=30.5647840531561, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789453, Length=249, Percent_Identity=30.9236947791165, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58427; Mature: 58427

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTIKIQTRLLIAFLLMALLLIGLSGLSISSMKTIRANANTVETNLLPSIMSLGELNSN
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
MMRIRVLTLRLLVSETQESREQVANVIRDLKLEIEKNQAQYEQLISMDNERAVYRAFEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QKTYYVEQDKLISFATSGKLDEAKLVLPQLYTLADEIVKDLRDLVAINKASSDDTRIVSI
HHHHHCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
TEYDSNFWLVIVTVIVASIIAIVIAFMLSNSINQPLQAAVKTAEIIAHGDLTQSISVSGD
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
DELTRLVTALQIMQRNLRDAIVHIGSSSSQLASAAEELNSVTEDSSRGLQLQNDEIQQAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHH
TAITEMSTAVDEVARTAQQASDASSESAKLAVEGKNRVEDTTAVITEINDEMTKSTTVIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLAAQVVSISKLLDVIRSVSEQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAHRTQV
HHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
SAGEIETMVRQVQVSAEAAVTSMVTTSEKTNQARIVADEATKALDQITTRIVAISDSNHV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHEEEEEECCCCE
IASAAEEQSTVAREIDNNIMTIRDLAAQTAAGAHQTSASSAELTRLAVDLNTLVVKFKV
EEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEHEEEEEEEEC
>Mature Secondary Structure
MLRTIKIQTRLLIAFLLMALLLIGLSGLSISSMKTIRANANTVETNLLPSIMSLGELNSN
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
MMRIRVLTLRLLVSETQESREQVANVIRDLKLEIEKNQAQYEQLISMDNERAVYRAFEQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
QKTYYVEQDKLISFATSGKLDEAKLVLPQLYTLADEIVKDLRDLVAINKASSDDTRIVSI
HHHHHCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
TEYDSNFWLVIVTVIVASIIAIVIAFMLSNSINQPLQAAVKTAEIIAHGDLTQSISVSGD
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEECCCC
DELTRLVTALQIMQRNLRDAIVHIGSSSSQLASAAEELNSVTEDSSRGLQLQNDEIQQAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHH
TAITEMSTAVDEVARTAQQASDASSESAKLAVEGKNRVEDTTAVITEINDEMTKSTTVIN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLAAQVVSISKLLDVIRSVSEQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAHRTQV
HHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCC
SAGEIETMVRQVQVSAEAAVTSMVTTSEKTNQARIVADEATKALDQITTRIVAISDSNHV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHEEEEEECCCCE
IASAAEEQSTVAREIDNNIMTIRDLAAQTAAGAHQTSASSAELTRLAVDLNTLVVKFKV
EEECHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEHEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]