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The map label for this gene is sucC

Identifier: 120598558

GI number: 120598558

Start: 2006116

End: 2007282

Strand: Direct

Name: sucC

Synonym: Sputw3181_1741

Alternate gene names: 120598558

Gene position: 2006116-2007282 (Clockwise)

Preceding gene: 120598557

Following gene: 120598559

Centisome position: 42.61

GC content: 47.73

Gene sequence:

>1167_bases
ATGAATTTGCATGAGTATCAGGCAAAATCCCTATTTGCCGAATATGGTTTACCAGTGTCAGAAGGTTTTGCATGTGATAC
AGCCCAAGAAGCTGTAGAAGCGGCAGGCCGTATTGGCGGAAATTTATGGGTTGTTAAGTGTCAAGTACACGCTGGCGGCC
GCGGTAAAGCGGGTGGCGTTAAAGTCACTGGCGATAAAGAAGAAATCAGAGCCTTTGCCGAACACTGGTTAGGCAAAAAT
CTGGTGACTTATCAAACAGATGAGAAAGGTCAGCCCGTTGCTAAAATTTTAGTAGAAAGCTGCACCGACATCGCTAACGA
ACTGTACTTAGGCGCAGTCGTTGACCGTAGCACACGCCGCGTCGTGTTTATGGCGTCAACTGAAGGTGGTGTTGAAATTG
AGAAAGTGGCAGAAGAAACGCCAGAACTCATTCACAAAGCGATTATCGATCCGCTAACAGGCCCACAGCCATATCAAGCC
CGTGATCTTGGCTTCAAACTGGGTTTGAATCCAACTCAAATGAAACAGTTCACTAAGATCTTTATGGGTCTGGCGACGAT
GTTCGTTGATCACGATTTTGCGCTACTTGAAATCAACCCACTGGTTATCACCACTGAAGGTAACCTGCACTGCCTAGACG
GTAAAATTGGTATCGATGGTAACGCACTGTTCCGTCAGCCAAAAGTTAAAGCAATGCACGACCCATCACAGGATGACGCC
CGTGAAGCCCACGCAGCGATGTTCGAACTGAACTACGTAGCATTAGACGGTAACGTTGGCTGTATGGTGAACGGTGCAGG
GCTTGCTATGGGTACGATGGACATCGTTAACCTGCACGGTGGCAAGCCAGCAAACTTCCTCGACGTAGGCGGCGGTGCGA
CTAAAGAACGTGTTGCTGAAGCGTTTAAAATCATTCTGTCTGATAGCAATGTGAAAGCGGTTCTGGTTAACATTTTCGGC
GGTATCGTACGTTGTGACATGATCGCTGAAGGTATTATTGGCGCCGTTAAAGAAGTGGGCGTTAAGGTTCCAGTTGTGGT
GCGTTTAGAAGGTACTAACGCTGAATTAGGCCGTGAAGTTCTGGCAAAATCTGGTCTTGATATCATTGCAGCTACCAGTC
TGACTGATGCGGCTGAACGAGTAGTTAAAGCTGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
ACACGTCTGCTGCTCGATCTATAAGAAAAAGCCAGACATACCCTCGTGACTGGCCCTAAGGGCCAGTTGGATTTGATTAG
AAGTATACGGATAGATCATC

Downstream 100 bases:

>100_bases
TGTCTGTCTTAATCAATAAAGATACCAAGGTAATTTGCCAAGGCTTTACCGGTGGTCAAGGTACATTCCATTCACAGCAA
GCTATCGATTACGGTACGCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAERVVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAERVVKAAEGK
>Mature_388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAERVVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.5470737913486, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=45.4780361757106, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=45.9016393442623, Blast_Score=305, Evalue=4e-83,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.319587628866, Blast_Score=592, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=44.4730077120823, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=41.75, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.7480916030534, Blast_Score=330, Evalue=3e-91,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=42.8211586901763, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=42.7480916030534, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=42.7480916030534, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=42.8934010152284, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=42.8934010152284, Blast_Score=292, Evalue=2e-79,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41384; Mature: 41384

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEHHEECCCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEEECCCCHHCCCCCCCCCCCCCCHHH
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREV
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAKSGLDIIAATSLTDAAERVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEHHEECCCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEEECCCCHHCCCCCCCCCCCCCCHHH
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREV
HHHHEECCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAKSGLDIIAATSLTDAAERVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA