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The map label for this gene is sucD [H]

Identifier: 120598559

GI number: 120598559

Start: 2007282

End: 2008154

Strand: Direct

Name: sucD [H]

Synonym: Sputw3181_1742

Alternate gene names: 120598559

Gene position: 2007282-2008154 (Clockwise)

Preceding gene: 120598558

Following gene: 120598560

Centisome position: 42.63

GC content: 47.77

Gene sequence:

>873_bases
ATGTCTGTCTTAATCAATAAAGATACCAAGGTAATTTGCCAAGGCTTTACCGGTGGTCAAGGTACATTCCATTCACAGCA
AGCTATCGATTACGGTACGCAAATGGTCGGTGGTGTGTCTCCTGGTAAAGGTGGGACTGAACATTTAGGCCTACCAGTGT
TTAACACAGTGAAAGACGCGGTTGCAGCAACTGGCGCAACAGCTTCTGTTATCTATGTTCCAGCACCTTTCTGTAAAGAC
GCTATTCTTGAAGCAATCGATGGTGGCATCGAGCTTATCGTTTGTATCACTGAAGGCATTCCTACACTGGATATGCTACA
AGTGAAAGTGAAGCTTGAAGAAACTGGCGTTCGTATGATCGGTCCTAACTGCCCAGGTGTTATCACCCCTGGTGAGTGTA
AGATCGGCATCATGCCAGGTCATATCCACTTAAAAGGTAAAGTGGGTATCGTTTCTCGTTCAGGTACTTTGACTTACGAA
GCGGTTAAGCAAACCACTGACGAAGGTTTCGGCCAATCTACTTGCGTAGGTATTGGTGGTGACCCAATTCCAGGTACTAA
CTTCATCGACGTATTGGAAATGTTCCAAAACGATCCACAGACTGAAGCCATCGTGATGATCGGTGAAATCGGTGGTACTG
CTGAAGAAGAAGCGGCGGCTTATATCAAAGCTCACGTGACTAAGCCTGTAGTTTCTTACATTGCCGGTGTCACTGCACCT
GCTGGTAAGCGTATGGGCCATGCTGGCGCGATTATCGCTGGCGGTAAAGGTACTGCTGCCGACAAGTTTGCAGCTTTAGA
AGCGGCGGGTGTGACCACAGTCCGCTCGTTAGCGGATATCGGCAAAGCGCTACGTGCTAAAACAGGTTGGTAA

Upstream 100 bases:

>100_bases
TAGGCCGTGAAGTTCTGGCAAAATCTGGTCTTGATATCATTGCAGCTACCAGTCTGACTGATGCGGCTGAACGAGTAGTT
AAAGCTGCGGAGGGCAAATA

Downstream 100 bases:

>100_bases
GCTAACCGTTTAAACACTAAAAGGCGCCTAAGGCGCCTTTTTTATTGGCGGTCATTTACGTGATGAAACCCAGCAAATGA
TGGGAATGGGATTGAGCTAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKAHVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW

Sequences:

>Translated_290_residues
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKAHVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
>Mature_289_residues
SVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKDA
ILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEA
VKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKAHVTKPVVSYIAGVTAPA
GKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=67.2473867595819, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=33.2046332046332, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=33.2046332046332, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=87.3684210526316, Blast_Score=503, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.2361111111111, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17553126, Length=289, Percent_Identity=62.6297577854671, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=30.9803921568627, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=30.9803921568627, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=52.7397260273973, Blast_Score=282, Evalue=4e-77,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=62.8472222222222, Blast_Score=334, Evalue=4e-92,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=58.3333333333333, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI281363477, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363475, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363473, Length=255, Percent_Identity=29.0196078431373, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29722; Mature: 29590

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDA
CEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VAATGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMI
HHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKAHVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDA
EEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VAATGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLQVKVKLEETGVRMI
HHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKAHVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]