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The map label for this gene is trpR [C]

Identifier: 120598098

GI number: 120598098

Start: 1453325

End: 1453600

Strand: Direct

Name: trpR [C]

Synonym: Sputw3181_1275

Alternate gene names: 120598098

Gene position: 1453325-1453600 (Clockwise)

Preceding gene: 120598096

Following gene: 120598100

Centisome position: 30.87

GC content: 37.32

Gene sequence:

>276_bases
ATGCGAGCAAATTGGGACTTAGTATTAAACAAGATTTTGAGTCATGGAAATTATGAAGATCTTTTTATGCTCCTTCATTT
ACTGTTAACTGAAGATGAGCGAAGTGCCATTGCTGGGCGGCTTAAAGTTTTCCAGCTACTGCTAAATAGTGAAATGAGTC
AACGTCAGATTGCAGCAGAATTTGAAGTCAGTATTGCCACTATTACTCGGTGCTCTAATTACCTTAAAAATATGACTCCC
GAGCATAGAGCGAAAATTCAGACATTAATAAGTTAG

Upstream 100 bases:

>100_bases
TTTTGTCTAGATGTAATGAAGAAGCGTAACAAGTTATTTGTTAGAGAAACAAATCTGGTAAACTGCCATGTAATGCTTTA
ACAGTAGTTATGGGGTGATT

Downstream 100 bases:

>100_bases
TGGAAAGAGATGGTTTTAAGGAAAAGTTCAATAAAAATGAGGCGCTTCCTTTTTAAGAAAGTACCTCATAATGCAAAATT
TGTGGTCGAGTTTATTTAAA

Product: Trp operon repressor

Products: NA

Alternate protein names: Trp Repressor

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MRANWDLVLNKILSHGNYEDLFMLLHLLLTEDERSAIAGRLKVFQLLLNSEMSQRQIAAEFEVSIATITRCSNYLKNMTP
EHRAKIQTLIS

Sequences:

>Translated_91_residues
MRANWDLVLNKILSHGNYEDLFMLLHLLLTEDERSAIAGRLKVFQLLLNSEMSQRQIAAEFEVSIATITRCSNYLKNMTP
EHRAKIQTLIS
>Mature_91_residues
MRANWDLVLNKILSHGNYEDLFMLLHLLLTEDERSAIAGRLKVFQLLLNSEMSQRQIAAEFEVSIATITRCSNYLKNMTP
EHRAKIQTLIS

Specific function: This Protein Is An Aporepressor. When Complexed With L- Tryptophan It Binds The Operator Region Of The Trp Operon (5'- ACTAGT-'3') And Prevents The Initiation Of Transcription. The Complex Also Regulates Trp Repressor Biosynthesis By Binding To Its Regula

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 10518; Mature: 10518

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRANWDLVLNKILSHGNYEDLFMLLHLLLTEDERSAIAGRLKVFQLLLNSEMSQRQIAAE
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FEVSIATITRCSNYLKNMTPEHRAKIQTLIS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRANWDLVLNKILSHGNYEDLFMLLHLLLTEDERSAIAGRLKVFQLLLNSEMSQRQIAAE
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FEVSIATITRCSNYLKNMTPEHRAKIQTLIS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA