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The map label for this gene is nrdR

Identifier: 120598056

GI number: 120598056

Start: 1396339

End: 1396788

Strand: Direct

Name: nrdR

Synonym: Sputw3181_1233

Alternate gene names: 120598056

Gene position: 1396339-1396788 (Clockwise)

Preceding gene: 120598055

Following gene: 120598057

Centisome position: 29.66

GC content: 49.78

Gene sequence:

>450_bases
ATGCATTGTCCATTTTGCAGCGCGACAGATACTAAAGTCATCGATTCTCGATTAGTGGCGGAAGGCCATCAAGTGCGCCG
TCGCCGAGAATGCACCGAATGCCATGAAAGATTTACCACCTTTGAAGGTGCCGAGTTAGTCATGCCTAGGGTGATCAAGC
GCGATGGTTCACGCCAACCCTTCGATGAAGAAAAACTCCAAAGTGGAATGTTGCGCGCCGTTGAAAAACGTCCTGTGTCT
ATGGATGAAATCGAGCAAGCGCTCAGCAAAATCAAGTCCACTCTGCGCGCCACGGGCGAGCGGGAAGTGCCGTCAGAAAT
GGTGGGTAACTTGATGATGGAACAATTGATGAACCTCGATAAAGTTGCCTATATACGTTTTGCTTCCGTATACCGCGCCT
TCGAAGACGTGTCTGAATTTGGCGAAGCCATCGCCAAACTGCAAAAGTAG

Upstream 100 bases:

>100_bases
CCATTTTTATTGCTAAAATCTTAGACTTAAACCAAACAGGCTAACCTTAGATAACATAGTAAAGCCAACGGCTTTACGTC
ATTCACTGGCAGGAGGCTCA

Downstream 100 bases:

>100_bases
TTATTCAGCTTTTGTCGCCTTAGAAGGTTGACGTGCAGTTGTCGCAGACGTAAAAAACAGATTTATAAGACAGGTGAAAG
CCGAAACCTTTAACAACAGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQSGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMNLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK

Sequences:

>Translated_149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQSGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMNLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
>Mature_149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQPFDEEKLQSGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMNLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=74.3243243243243, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17117; Mature: 17117

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLQSGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMNLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHH
KVAYIRFASVYRAFEDVSEFGEAIAKLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGSRQP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLQSGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMVGNLMMEQLMNLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCHH
KVAYIRFASVYRAFEDVSEFGEAIAKLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA