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The map label for this gene is zntR [H]

Identifier: 120597993

GI number: 120597993

Start: 1321291

End: 1321755

Strand: Direct

Name: zntR [H]

Synonym: Sputw3181_1170

Alternate gene names: 120597993

Gene position: 1321291-1321755 (Clockwise)

Preceding gene: 120597987

Following gene: 120597994

Centisome position: 28.06

GC content: 42.58

Gene sequence:

>465_bases
ATGAAACCTAGTTTAAACTCTGTAGTTACTATAGAGTCAATAGGCAGTATCGAGATGATCAAGATTGGAGAGCTGGCAAA
AATCTCTGGCTGTTCTGTGCAAACCATCCGTCACTATGAAAAGGAGCAGCTTCTTGCGGCGAAACTACGTAGCGATGGTA
ATTTCCGCCTCTACGATCACGCTGATATCGAGCGGTTGCTATTTATTAAACACTGCCGGAGTTTAGATCTGAGTTTGGCA
GAAATTCGTCAGTTACTGAGTTTGAATGACTCGCCAATGTCGCAGTGTGATGATGTTAATCAGATGATTGAACAGCATAT
CGAGCAGGTAGAACGTCGCATAGCGGATTTAACGCAGCTTAATAAACAACTAAAGGCTTTACGTCTTAGCTGCAACTCGA
AGCGCACGGTAGAGCACTGTGGTATTTTAAAACAATTGAATGAAGCCGTTAGTCAAACCAACTAA

Upstream 100 bases:

>100_bases
ATCAGGTGCATCAACGGCGCTATTTTCACTGTTGCCCGTTTCGCTACACTTATCATTGGAACAGCATTTTGCATTCATAA
CCGATAAACCTTGGGTTGAT

Downstream 100 bases:

>100_bases
GTTGTTATCAGCAATAAATAGGTGAGTCTTAATGCACCAGCACAACCATTCATATATCAAAGACGACAGCGACAACCGGA
TCGCTATGGCTTTTTTCTTA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKPSLNSVVTIESIGSIEMIKIGELAKISGCSVQTIRHYEKEQLLAAKLRSDGNFRLYDHADIERLLFIKHCRSLDLSLA
EIRQLLSLNDSPMSQCDDVNQMIEQHIEQVERRIADLTQLNKQLKALRLSCNSKRTVEHCGILKQLNEAVSQTN

Sequences:

>Translated_154_residues
MKPSLNSVVTIESIGSIEMIKIGELAKISGCSVQTIRHYEKEQLLAAKLRSDGNFRLYDHADIERLLFIKHCRSLDLSLA
EIRQLLSLNDSPMSQCDDVNQMIEQHIEQVERRIADLTQLNKQLKALRLSCNSKRTVEHCGILKQLNEAVSQTN
>Mature_154_residues
MKPSLNSVVTIESIGSIEMIKIGELAKISGCSVQTIRHYEKEQLLAAKLRSDGNFRLYDHADIERLLFIKHCRSLDLSLA
EIRQLLSLNDSPMSQCDDVNQMIEQHIEQVERRIADLTQLNKQLKALRLSCNSKRTVEHCGILKQLNEAVSQTN

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=135, Percent_Identity=37.7777777777778, Blast_Score=102, Evalue=8e-24,
Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=27.34375, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17515; Mature: 17515

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSLNSVVTIESIGSIEMIKIGELAKISGCSVQTIRHYEKEQLLAAKLRSDGNFRLYDH
CCCCCCCEEEECCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECH
ADIERLLFIKHCRSLDLSLAEIRQLLSLNDSPMSQCDDVNQMIEQHIEQVERRIADLTQL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKQLKALRLSCNSKRTVEHCGILKQLNEAVSQTN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPSLNSVVTIESIGSIEMIKIGELAKISGCSVQTIRHYEKEQLLAAKLRSDGNFRLYDH
CCCCCCCEEEECCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECH
ADIERLLFIKHCRSLDLSLAEIRQLLSLNDSPMSQCDDVNQMIEQHIEQVERRIADLTQL
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKQLKALRLSCNSKRTVEHCGILKQLNEAVSQTN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]