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The map label for this gene is purP [H]

Identifier: 120597800

GI number: 120597800

Start: 1102211

End: 1103500

Strand: Direct

Name: purP [H]

Synonym: Sputw3181_0970

Alternate gene names: 120597800

Gene position: 1102211-1103500 (Clockwise)

Preceding gene: 120597799

Following gene: 120597801

Centisome position: 23.41

GC content: 46.28

Gene sequence:

>1290_bases
ATGTTAGAAAAGCTGTTCAAACTAAAACAAAATCAAACGAGCCTCAAGCAGGAAGCTATTGCAGGTTTAACCACATTTAT
GACGATGGCCTACATCATTTTTGTCAATCCAATGATGTTAGCCGATGCAGGCATGGACCACGGGGCAGTATTTGTTGCCA
CCTGCCTTGCAGCAGCAATTGGTTGTTTAGTCATGGGATTAATGGCTAATTATCCGATTGCATTAGCACCGGGAATGGGG
CTTAACGCCTTTTTCACTTACACGGTTGTGGGTGAAATGGGTTATAGCTGGGAGACAGCCTTAGGTGCCGTGTTCCTATC
GGGAATTTGCTTTTTAATCTTGTCCTTAGTGCGTATTCGTGAATGGATTGTTAACAGCATTCCCGTGTCGTTACGCCTAG
GTATTGCCGCTGGTATTGGTTTATTTCTTGCGCTGATTGGTCTTAAAAGTGCGGGCATTGTTGTTGCTAATCCTGCGACC
TTAGTCACTATGGGTGATATTACTACTTTTCCGGCCGTAATGGCAGTATTGGGCTTTTTCCTGATTATTGCCATGGTGCA
AAGGGGAATGAAGTCGGCGGTAATTTTAAGCATCTTAATTATCACCGGACTTGGATTGATCTTTGGTGATGTGCATTACA
ACGGCATAGTGTCTATGCCGCCTTCAATTGCCCCGACCTTTATGAAGATGGATTTATCCCAAGTCTTTGAAGTCACGATG
CTATCAGTCGTGTTTGCCTTCTTGTTTGTGGATTTATTTGATACATCAGGCACCTTAGTTGCGGTTGCCCAACGCGGTGG
TTTTCTCGATGAGAAAGGTCGTTTACCTCGTTTAAATCGTGCTTTGACCGCAGACAGTTTAGCCACTATCGCTGGTGCCG
CTTGTGGTACTTCCACCACGACAAGCTATATCGAAAGTACCGCGGGAGTGAGTGCGGGAGGGCGTACAGGATTAACCGCT
GTGGTGGTGGGATTATTGTTTATTGCTGCATTGTTCCTATCGCCATTGGCGGGGATGATTCCGGCCTATGCAACAGCGGG
CACCCTGTTTTATGTGGCTATTTTAATGATGTCTGGCCTTGTGCATGTTGAGTGGGAAGATTTAACTGAAGCCGCGCCTG
TGGTGGTGGTGTGTATCTTAATGCCGCTGACGTTCTCTATTGCATCGGGGATTGCGCTGGGGATTATCTCCTATGCGGCG
ATTAAAATACTCACGGGTCGCTTTAGCGATCTCAATGTGGGTATCATCGTGTTAGCGGCATTATTTGTGGCTAAGTTTGT
CTATGCTTGA

Upstream 100 bases:

>100_bases
ACCAGCCTAAACTCCTTATAATCTGCCGCAAATGTAATCGCGCTACATATTCCTTACATTTAAATACCCTACCTACTTAA
AATAAAAGGAACCCAGTTCC

Downstream 100 bases:

>100_bases
TGCTGTTTAATCGTGAGCTAGCCTAGTGGGTTAGATTGTCTACAATAGGCAATATTTTTTGAGGGTCATCTAATCGATGG
CCCTTTTTACTGCGTGATTA

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPVSLRLGIAAGIGLFLALIGLKSAGIVVANPAT
LVTMGDITTFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLIFGDVHYNGIVSMPPSIAPTFMKMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAACGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIASGIALGIISYAA
IKILTGRFSDLNVGIIVLAALFVAKFVYA

Sequences:

>Translated_429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPVSLRLGIAAGIGLFLALIGLKSAGIVVANPAT
LVTMGDITTFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLIFGDVHYNGIVSMPPSIAPTFMKMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAACGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIASGIALGIISYAA
IKILTGRFSDLNVGIIVLAALFVAKFVYA
>Mature_429_residues
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAIGCLVMGLMANYPIALAPGMG
LNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIREWIVNSIPVSLRLGIAAGIGLFLALIGLKSAGIVVANPAT
LVTMGDITTFPAVMAVLGFFLIIAMVQRGMKSAVILSILIITGLGLIFGDVHYNGIVSMPPSIAPTFMKMDLSQVFEVTM
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAACGTSTTTSYIESTAGVSAGGRTGLTA
VVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGLVHVEWEDLTEAAPVVVVCILMPLTFSIASGIALGIISYAA
IKILTGRFSDLNVGIIVLAALFVAKFVYA

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=53.0373831775701, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=50, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790499, Length=430, Percent_Identity=38.3720930232558, Blast_Score=284, Evalue=8e-78,
Organism=Escherichia coli, GI48994909, Length=432, Percent_Identity=38.1944444444444, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45014; Mature: 45014

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAI
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCLVMGLMANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPVSLRLGIAAGIGLFLALIGLKSAGIVVANPATLVTMGDITTFPAVMAVLGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHH
LIIAMVQRGMKSAVILSILIITGLGLIFGDVHYNGIVSMPPSIAPTFMKMDLSQVFEVTM
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAACGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
TSYIESTAGVSAGGRTGLTAVVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VHVEWEDLTEAAPVVVVCILMPLTFSIASGIALGIISYAAIKILTGRFSDLNVGIIVLAA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LFVAKFVYA
HHHHHHHCC
>Mature Secondary Structure
MLEKLFKLKQNQTSLKQEAIAGLTTFMTMAYIIFVNPMMLADAGMDHGAVFVATCLAAAI
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GCLVMGLMANYPIALAPGMGLNAFFTYTVVGEMGYSWETALGAVFLSGICFLILSLVRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIVNSIPVSLRLGIAAGIGLFLALIGLKSAGIVVANPATLVTMGDITTFPAVMAVLGFF
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHH
LIIAMVQRGMKSAVILSILIITGLGLIFGDVHYNGIVSMPPSIAPTFMKMDLSQVFEVTM
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHH
LSVVFAFLFVDLFDTSGTLVAVAQRGGFLDEKGRLPRLNRALTADSLATIAGAACGTSTT
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHH
TSYIESTAGVSAGGRTGLTAVVVGLLFIAALFLSPLAGMIPAYATAGTLFYVAILMMSGL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VHVEWEDLTEAAPVVVVCILMPLTFSIASGIALGIISYAAIKILTGRFSDLNVGIIVLAA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LFVAKFVYA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]