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The map label for this gene is adrA [H]

Identifier: 120597689

GI number: 120597689

Start: 969684

End: 970655

Strand: Direct

Name: adrA [H]

Synonym: Sputw3181_0859

Alternate gene names: 120597689

Gene position: 969684-970655 (Clockwise)

Preceding gene: 120597688

Following gene: 120597691

Centisome position: 20.59

GC content: 44.14

Gene sequence:

>972_bases
ATGGAATTACCTCCCATCCCAGAAAATGAGCTGCAACGTTTAGCCACGTTGCGAGCTCTCAATGTGTTAGATACCGATGC
AGAGGAGCGCTTCGACCGTATCACTCGCCTGACTCGGCGAATTTTTTCGTTGCCAATTTGTGTCATTACCCTTGTAGATG
CTCAGCGCCAGTGGTTTAAATCTCGCCAAGGACTTGAAATAACTGAAACATCACGGGATATTTCCCTTTGTGCCCACGCA
ATAAACTATGAGGGTATTTTTATTATTAACGATACTCTTCTCGATCCGCGGTTTTGTGATAATCCTTTTGTGGCACAAGA
ACCCTTTATTCGTTTTTATGCAGGTTACCCACTCACGATAAATCATCATTACCGAGTAGGAACACTATGTGTAAATGACA
CTGAACCTCGGGAGTTTAGCCAAGAAGATATTGAAACCTTGACAGATCTCGGCCAAATGGTTGAGGCCGAGTTATTATCT
ATCGCGCAGAATACCTTAGATCCTTTAACGGGCATTTCAAATCGTCGAGGATTTGAGTTATTAGCACATCAGGCCATAGC
GAGTTGTCGACGCACTGAATCGGAGGCGGCTTTAGTGTTCTTCGATCTCGATTTTTTTAAAGAAGTGAATGATAGCTTTG
GTCATCGTAAGGGCGATCAGGTGTTATATGATTTTGCCCATATCTTAATGACTGCTTTTAGGGAGTCGGATGTGATCGCA
AGGCTTGGCGGCGATGAGTTTGTGGTGCTGTTAAGTTTTGTGCATAGAGATACAGTTAATCGGGTCATCGAGCGCTTTAC
GCAGTTACTTGAGCAATATAATCAACAGCATCCTAAGCAACATCGATTGGCGACCAGCATAGGTATCGCCCATTGGACGC
CGGATTCAGATATGGGCTTAGAGGATCTGTTAGATTCCGCCGATAAAGCCATGTATCAGAATAAAGCCGCACATCACAGT
GATGCATCTTAA

Upstream 100 bases:

>100_bases
TATCGAGCCGTGCTTGAATCGTAAACTTTTGTCTATTCAAATTCTCTAGGTCGGGGGATTTGGTCTAAAGTTTAATGCAG
AGCAGCTATTAGAGAGTGCC

Downstream 100 bases:

>100_bases
ATTGCTTATGCCAGATGAAAAGGGAGACAATAATGTCTCCCTTTTCATTGGATCTGATTAGGCGAAAAACTAAACACCGG
CGTTAAGCCGTAATGAGCAT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MELPPIPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICVITLVDAQRQWFKSRQGLEITETSRDISLCAHA
INYEGIFIINDTLLDPRFCDNPFVAQEPFIRFYAGYPLTINHHYRVGTLCVNDTEPREFSQEDIETLTDLGQMVEAELLS
IAQNTLDPLTGISNRRGFELLAHQAIASCRRTESEAALVFFDLDFFKEVNDSFGHRKGDQVLYDFAHILMTAFRESDVIA
RLGGDEFVVLLSFVHRDTVNRVIERFTQLLEQYNQQHPKQHRLATSIGIAHWTPDSDMGLEDLLDSADKAMYQNKAAHHS
DAS

Sequences:

>Translated_323_residues
MELPPIPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICVITLVDAQRQWFKSRQGLEITETSRDISLCAHA
INYEGIFIINDTLLDPRFCDNPFVAQEPFIRFYAGYPLTINHHYRVGTLCVNDTEPREFSQEDIETLTDLGQMVEAELLS
IAQNTLDPLTGISNRRGFELLAHQAIASCRRTESEAALVFFDLDFFKEVNDSFGHRKGDQVLYDFAHILMTAFRESDVIA
RLGGDEFVVLLSFVHRDTVNRVIERFTQLLEQYNQQHPKQHRLATSIGIAHWTPDSDMGLEDLLDSADKAMYQNKAAHHS
DAS
>Mature_323_residues
MELPPIPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICVITLVDAQRQWFKSRQGLEITETSRDISLCAHA
INYEGIFIINDTLLDPRFCDNPFVAQEPFIRFYAGYPLTINHHYRVGTLCVNDTEPREFSQEDIETLTDLGQMVEAELLS
IAQNTLDPLTGISNRRGFELLAHQAIASCRRTESEAALVFFDLDFFKEVNDSFGHRKGDQVLYDFAHILMTAFRESDVIA
RLGGDEFVVLLSFVHRDTVNRVIERFTQLLEQYNQQHPKQHRLATSIGIAHWTPDSDMGLEDLLDSADKAMYQNKAAHHS
DAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=155, Percent_Identity=34.1935483870968, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081977, Length=262, Percent_Identity=30.5343511450382, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=150, Percent_Identity=36, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=150, Percent_Identity=30.6666666666667, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787262, Length=152, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081881, Length=149, Percent_Identity=31.5436241610738, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=32.2981366459627, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=153, Percent_Identity=31.3725490196078, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=27.2151898734177, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=33.9285714285714, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788085, Length=153, Percent_Identity=28.1045751633987, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 37029; Mature: 37029

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPPIPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICVITLVDAQRQWFK
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQGLEITETSRDISLCAHAINYEGIFIINDTLLDPRFCDNPFVAQEPFIRFYAGYPLTI
HCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCEEE
NHHYRVGTLCVNDTEPREFSQEDIETLTDLGQMVEAELLSIAQNTLDPLTGISNRRGFEL
CCCEEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LAHQAIASCRRTESEAALVFFDLDFFKEVNDSFGHRKGDQVLYDFAHILMTAFRESDVIA
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
RLGGDEFVVLLSFVHRDTVNRVIERFTQLLEQYNQQHPKQHRLATSIGIAHWTPDSDMGL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECCCCCCCH
EDLLDSADKAMYQNKAAHHSDAS
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELPPIPENELQRLATLRALNVLDTDAEERFDRITRLTRRIFSLPICVITLVDAQRQWFK
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRQGLEITETSRDISLCAHAINYEGIFIINDTLLDPRFCDNPFVAQEPFIRFYAGYPLTI
HCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCEEE
NHHYRVGTLCVNDTEPREFSQEDIETLTDLGQMVEAELLSIAQNTLDPLTGISNRRGFEL
CCCEEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LAHQAIASCRRTESEAALVFFDLDFFKEVNDSFGHRKGDQVLYDFAHILMTAFRESDVIA
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHH
RLGGDEFVVLLSFVHRDTVNRVIERFTQLLEQYNQQHPKQHRLATSIGIAHWTPDSDMGL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECCCCCCCH
EDLLDSADKAMYQNKAAHHSDAS
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]