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The map label for this gene is aer [H]

Identifier: 120597665

GI number: 120597665

Start: 938394

End: 939962

Strand: Direct

Name: aer [H]

Synonym: Sputw3181_0835

Alternate gene names: 120597665

Gene position: 938394-939962 (Clockwise)

Preceding gene: 120597664

Following gene: 120597667

Centisome position: 19.93

GC content: 45.12

Gene sequence:

>1569_bases
ATGCGTAAAAATTTGCCCATTACAGGAAATGAAAGAACATTTCCGAAGGAACAGCAGCTTATTTCATCTACTGATATTAA
GGGCACTATCTTGCATTGTAATGATGCATTTATCTCCATTAGTGGTTTTAGTCGTGAAGAGTTAGTTGGCAAACCCCATA
ACATAGTTCGACATCCTGATATGCCTGAAGCGGCATTTAAGACGATGTGGAGCTATTTACAGCAGGGCAAACCTTGGATG
GGGCTTGTAAAAAACCGCTGTAAGAATGGGGATTATTATTGGGTTAATGCCTATGTGACTCCAGTGACGGAACATGGACG
TGTAGTGGGGTATGAATCGGTTCGCTCAGTCCCAAGTCGAGAGCAGGTAGCCCATGCAGAGCGTTTATACACGGCAATCA
ATGCAGGAAAAAATCCTCAAAGCAGTCTTTCAACCCTGATGGCTAATCTTCGTTGGGTAAGCCTACCTGCGATCGCTATG
ATTATTTCATTACTGCTATGGTGGCGATTAGGCCCAACAGAAGCGTCTATTGCTTTTCTTATCACAGCGTTACTTAGCTA
TGGTTTGGGAGTATATCGTTTAAACAGCACACTTACTCACCTTGTGGAATTACTGCCAACCCCTTTTACCGACCCACTTG
CAGTTGCTTCCTATGCAAAACATCGTGGAATATTGGGGCAGTTGGAGGTTGCGGTATTAGCGGAATCAGCCCATTTAAAT
ACAGTGTTAACTCGGATCGAAGATGCCTCGACTAAAGTGGCCTCACAATCGGATCAAGTGATGCATTTATCTGTAGAATC
AACGGACTGTATCCGTAAGCAGCAAGTGCAAACAGAACAAGTTGCGACCGCCATGAATCAGATGACGACAACGATTGCTG
AAATATCGTCACATGTGCAGGATACCGCAACCAAAGCCAGCGATGTTGATGCGTTAGCCTGTTCTGGTTCTGCGGTGGCA
GGACAAACACGTAGTGCAATGCAGCAGCTACAAAAAACCGTCAATGATATTAGCCAGTCGGTGGCGGATCTTGCCGATCA
GACAGATAAAATTGTGGGCGCGGCACAATTAATTGAACAGATCGCCGAACAAACCAACTTACTTGCCCTTAATGCTGCAA
TTGAGGCTGCAAGAGCAGGTGATCAAGGCCGAGGCTTTGCTGTGGTCGCCGATGAAGTGAGGCTGCTCGCGTCGCGAACT
ACCGCATCAACTAAAGAAATTTATGATATTATTCAACTGCTTTCGACCAAAGCTAAAGCCTCAGTATTGATTGCTCAAAA
TGGATGTAAAGATACTGAACAGGGGGTTGCTCAAGTCGGATTAGCTGAAAAGGCATTAGAAGGCATTAGTGTTGCAGTGA
CGAGTATCGCCACTATGGCGGTGCAAATGGCTGCTGCGGTGGAAGAACAAGCCCATGTTGCTGAAGATATTAATCAACAA
ATTGTGATTATTTCTGAGCTTGCCAGTACTTCATTAGAGCAAGGCACAGAGGTCAGTGAAAGTGGCAAAAATCTACAAAT
GACATCAGAACAATTGCACGAGCTGGTAGAGCGCTTCCGTAAGGTATGA

Upstream 100 bases:

>100_bases
AAGCCTGATTTAGCTGCTAAATTTTTATCAGTCATTCCAATCTTAAACAAAATTTAGTTGATGTAGTCCCTGTTGTGGTT
CACTAAGGAGAGTGTCACAA

Downstream 100 bases:

>100_bases
AATAAATAAGCAAGGATTGTAAAAATGCAAACGCCCAAATTCGCGTGGATTTGGGCGTTTGTTTGAGCTTGATACTAAGT
CGTTTTTCTTGTTAAAGACG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MRKNLPITGNERTFPKEQQLISSTDIKGTILHCNDAFISISGFSREELVGKPHNIVRHPDMPEAAFKTMWSYLQQGKPWM
GLVKNRCKNGDYYWVNAYVTPVTEHGRVVGYESVRSVPSREQVAHAERLYTAINAGKNPQSSLSTLMANLRWVSLPAIAM
IISLLLWWRLGPTEASIAFLITALLSYGLGVYRLNSTLTHLVELLPTPFTDPLAVASYAKHRGILGQLEVAVLAESAHLN
TVLTRIEDASTKVASQSDQVMHLSVESTDCIRKQQVQTEQVATAMNQMTTTIAEISSHVQDTATKASDVDALACSGSAVA
GQTRSAMQQLQKTVNDISQSVADLADQTDKIVGAAQLIEQIAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRLLASRT
TASTKEIYDIIQLLSTKAKASVLIAQNGCKDTEQGVAQVGLAEKALEGISVAVTSIATMAVQMAAAVEEQAHVAEDINQQ
IVIISELASTSLEQGTEVSESGKNLQMTSEQLHELVERFRKV

Sequences:

>Translated_522_residues
MRKNLPITGNERTFPKEQQLISSTDIKGTILHCNDAFISISGFSREELVGKPHNIVRHPDMPEAAFKTMWSYLQQGKPWM
GLVKNRCKNGDYYWVNAYVTPVTEHGRVVGYESVRSVPSREQVAHAERLYTAINAGKNPQSSLSTLMANLRWVSLPAIAM
IISLLLWWRLGPTEASIAFLITALLSYGLGVYRLNSTLTHLVELLPTPFTDPLAVASYAKHRGILGQLEVAVLAESAHLN
TVLTRIEDASTKVASQSDQVMHLSVESTDCIRKQQVQTEQVATAMNQMTTTIAEISSHVQDTATKASDVDALACSGSAVA
GQTRSAMQQLQKTVNDISQSVADLADQTDKIVGAAQLIEQIAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRLLASRT
TASTKEIYDIIQLLSTKAKASVLIAQNGCKDTEQGVAQVGLAEKALEGISVAVTSIATMAVQMAAAVEEQAHVAEDINQQ
IVIISELASTSLEQGTEVSESGKNLQMTSEQLHELVERFRKV
>Mature_522_residues
MRKNLPITGNERTFPKEQQLISSTDIKGTILHCNDAFISISGFSREELVGKPHNIVRHPDMPEAAFKTMWSYLQQGKPWM
GLVKNRCKNGDYYWVNAYVTPVTEHGRVVGYESVRSVPSREQVAHAERLYTAINAGKNPQSSLSTLMANLRWVSLPAIAM
IISLLLWWRLGPTEASIAFLITALLSYGLGVYRLNSTLTHLVELLPTPFTDPLAVASYAKHRGILGQLEVAVLAESAHLN
TVLTRIEDASTKVASQSDQVMHLSVESTDCIRKQQVQTEQVATAMNQMTTTIAEISSHVQDTATKASDVDALACSGSAVA
GQTRSAMQQLQKTVNDISQSVADLADQTDKIVGAAQLIEQIAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRLLASRT
TASTKEIYDIIQLLSTKAKASVLIAQNGCKDTEQGVAQVGLAEKALEGISVAVTSIATMAVQMAAAVEEQAHVAEDINQQ
IVIISELASTSLEQGTEVSESGKNLQMTSEQLHELVERFRKV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=473, Percent_Identity=32.76955602537, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1788195, Length=269, Percent_Identity=33.0855018587361, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787690, Length=248, Percent_Identity=34.2741935483871, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367378, Length=136, Percent_Identity=40.4411764705882, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788194, Length=313, Percent_Identity=27.4760383386581, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56606; Mature: 56606

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLPITGNERTFPKEQQLISSTDIKGTILHCNDAFISISGFSREELVGKPHNIVRHPD
CCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHCCCCCCCCCCCC
MPEAAFKTMWSYLQQGKPWMGLVKNRCKNGDYYWVNAYVTPVTEHGRVVGYESVRSVPSR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEHHHHHCCCCH
EQVAHAERLYTAINAGKNPQSSLSTLMANLRWVSLPAIAMIISLLLWWRLGPTEASIAFL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITALLSYGLGVYRLNSTLTHLVELLPTPFTDPLAVASYAKHRGILGQLEVAVLAESAHLN
HHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TVLTRIEDASTKVASQSDQVMHLSVESTDCIRKQQVQTEQVATAMNQMTTTIAEISSHVQ
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTATKASDVDALACSGSAVAGQTRSAMQQLQKTVNDISQSVADLADQTDKIVGAAQLIEQ
HHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRLLASRTTASTKEIYDIIQLLSTKAKA
HHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHH
SVLIAQNGCKDTEQGVAQVGLAEKALEGISVAVTSIATMAVQMAAAVEEQAHVAEDINQQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVIISELASTSLEQGTEVSESGKNLQMTSEQLHELVERFRKV
EEEHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKNLPITGNERTFPKEQQLISSTDIKGTILHCNDAFISISGFSREELVGKPHNIVRHPD
CCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHCCCCCCCCCCCC
MPEAAFKTMWSYLQQGKPWMGLVKNRCKNGDYYWVNAYVTPVTEHGRVVGYESVRSVPSR
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEHHHHHCCCCH
EQVAHAERLYTAINAGKNPQSSLSTLMANLRWVSLPAIAMIISLLLWWRLGPTEASIAFL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITALLSYGLGVYRLNSTLTHLVELLPTPFTDPLAVASYAKHRGILGQLEVAVLAESAHLN
HHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TVLTRIEDASTKVASQSDQVMHLSVESTDCIRKQQVQTEQVATAMNQMTTTIAEISSHVQ
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTATKASDVDALACSGSAVAGQTRSAMQQLQKTVNDISQSVADLADQTDKIVGAAQLIEQ
HHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAEQTNLLALNAAIEAARAGDQGRGFAVVADEVRLLASRTTASTKEIYDIIQLLSTKAKA
HHHHHCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHH
SVLIAQNGCKDTEQGVAQVGLAEKALEGISVAVTSIATMAVQMAAAVEEQAHVAEDINQQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVIISELASTSLEQGTEVSESGKNLQMTSEQLHELVERFRKV
EEEHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]