Click here to switch to the map view.

The map label for this gene is ttdR [H]

Identifier: 120597335

GI number: 120597335

Start: 542248

End: 543174

Strand: Direct

Name: ttdR [H]

Synonym: Sputw3181_0504

Alternate gene names: 120597335

Gene position: 542248-543174 (Clockwise)

Preceding gene: 120597332

Following gene: 120597338

Centisome position: 11.52

GC content: 45.95

Gene sequence:

>927_bases
ATGCTAATTAATGATTTAGCTTTGTTCGTGCGAGTCGCTGATTGCGGTAATATATCTGCCGCAGCAGCCGAGATGGATAT
CTCGGCAGCTTCTGCCAGTGCTGCAATAAAACGGCTTGAGAAACAGCTTGATACTAGTTTATTTATCCGCACTACACGCA
GCTTACGTTTGACTGTGCAAGGTGAACGTTATCTTATTCATTGCCGACGTGCGCTAAGCGATTTAGCACTTGGCGAACAG
GCTATCGCCAGTGATAAAGGTAAAATATCCGGCACCTTAAGTCTTTCGGTTTCTTCAGACTTTGGCCGTAATCTGTTTGT
GCCTTGGCTCGACGAGTTTTTGCTCGATTTCCCTCAACTGCTAGTGCGCTTGCACCTTGGCGACAATATCAGCAGTTTTT
ACCACGATAAAATTGATGTCGCCGTGCGCTATGGAAAACCGCAGGATTCTAATCAAGTGGCTTTTCCTATCTGTAGTGTT
GATCGTGTTTTGTGTGCCTCACCTGAATATCTCGCCAAGTTTGGTGTGCTTGATTCATTAGAACAATTAGTTGAGCATAA
TTGCTTGTTTTATAAGTTAGATGATCGCACCCACGATCAATGGCTATTTAGGCGTGATGGTCAAGAATTCAAAGTGCGTG
TCACGGGCAATCGTAGTGCTAATGATGCCGAGATTGCCCGCCGTTGGGCTGTTGCTGGCAAAGGGTTGGTATTTAAGTCG
AGTCTAGATCTGGCCGATGACTTAATCTCAGGGCGATTAGTACGTTTGTTGCCTGAGTATCAGGGGGAGCCCGTCGATTT
GTACTTAGTGTGCCCAGGACGTGAACATGTCACGCCCGTCGTGCTCTTACTGCGGGAAATGCTCCGGCAGCGAACACTGG
CTCTAAGTAAAAACTTGAGTAAAATATTAGCAGTGAAAAAATCTTAG

Upstream 100 bases:

>100_bases
TTGTTTGAGTGTACTTGTATCGTGTAGCCATTGTGTGGAAGATTAGCCAAGAGATAAACAGGATAAAGTTTGTAATTTTT
TCAAAGGATTTTTGATAATC

Downstream 100 bases:

>100_bases
ATAACAAAAAAGCCGCATAATGCGGCTTTTAGCTTAGAGACTCACTGAGATTTAAGACTTAGTGCGTTTCATGGCGGTAA
AGAACTCTTCGTTAGTCTTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLLVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGVLDSLEQLVEHNCLFYKLDDRTHDQWLFRRDGQEFKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTLALSKNLSKILAVKKS

Sequences:

>Translated_308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLLVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGVLDSLEQLVEHNCLFYKLDDRTHDQWLFRRDGQEFKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTLALSKNLSKILAVKKS
>Mature_308_residues
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQGERYLIHCRRALSDLALGEQ
AIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQLLVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSV
DRVLCASPEYLAKFGVLDSLEQLVEHNCLFYKLDDRTHDQWLFRRDGQEFKVRVTGNRSANDAEIARRWAVAGKGLVFKS
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTLALSKNLSKILAVKKS

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=34.6153846153846, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=31.438127090301, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=29.6296296296296, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786401, Length=255, Percent_Identity=29.4117647058824, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789639, Length=265, Percent_Identity=29.811320754717, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=25.3623188405797, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786448, Length=277, Percent_Identity=26.7148014440433, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789173, Length=282, Percent_Identity=25.886524822695, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=162, Percent_Identity=27.1604938271605, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=129, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34463; Mature: 34463

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQ
CCCHHEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
LVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSVDRVLCASPEYLAKFGVLDSL
HHHHHCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHHHHH
EQLVEHNCLFYKLDDRTHDQWLFRRDGQEFKVRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTLALSKNLS
CCHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHH
KILAVKKS
HHHEECCC
>Mature Secondary Structure
MLINDLALFVRVADCGNISAAAAEMDISAASASAAIKRLEKQLDTSLFIRTTRSLRLTVQ
CCCHHEEEEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECEEEEEEC
GERYLIHCRRALSDLALGEQAIASDKGKISGTLSLSVSSDFGRNLFVPWLDEFLLDFPQL
CCHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
LVRLHLGDNISSFYHDKIDVAVRYGKPQDSNQVAFPICSVDRVLCASPEYLAKFGVLDSL
HHHHHCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCHHHHHHHHHHHHH
EQLVEHNCLFYKLDDRTHDQWLFRRDGQEFKVRVTGNRSANDAEIARRWAVAGKGLVFKS
HHHHHCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
SLDLADDLISGRLVRLLPEYQGEPVDLYLVCPGREHVTPVVLLLREMLRQRTLALSKNLS
CCHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCHH
KILAVKKS
HHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]