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The map label for this gene is moaC

Identifier: 120597075

GI number: 120597075

Start: 269640

End: 270116

Strand: Direct

Name: moaC

Synonym: Sputw3181_0244

Alternate gene names: 120597075

Gene position: 269640-270116 (Clockwise)

Preceding gene: 120597074

Following gene: 120597076

Centisome position: 5.73

GC content: 49.27

Gene sequence:

>477_bases
ATGAGCAATGTATTTACCCATATTAATGCCGATGGCAATGCCCATATGGTCGATGTGACCGAAAAGGCCGTCACTGAACG
CGAAGCCCGCGCCGAAGCTTTTATTGAGATGGCGAGCACGACACTCGAGATGATCATGAGTGGCAGCCACCACAAAGGTG
ATGTGTTTGCGACCGCGCGTATTGCGGGTATCCAAGCCGCAAAAAAAACCTCAGATCTTATCCCTTTATGCCATCCATTA
ATGCTCACTAAAGTGGAGGTCGATTTAGAGGCGCAGCCTGAACATAACCGTGTGCGCATCACTAGCCTGTGTAAATTATC
CGGTAAAACGGGTGTAGAGATGGAAGCGTTAACTGCGGCTTCAGTGGCGGCGTTAACTATCTATGACATGTGCAAGGCCG
TGCAAAAAGATATGGTGATCTCCCAAGTCCGTCTGTTGGAAAAGCGTGGCGGCAAGTCGGGACATTTTAAGGTTTAG

Upstream 100 bases:

>100_bases
TAGATCTGTATTTAGGTGTTTTGTCATCGCTAATGTAGCGCGAGTATAAGCCCAATTTTCCTTGCACTTTGTTTTGACCT
CACATGAAAGGATCGCTCCA

Downstream 100 bases:

>100_bases
CGGATCAAAAATGAGAGAAGACTATGATTAACGTGTTGTTTTTTGCTCAAGTTCGAGAATTATTGGGTACAGCTAAATTA
AGTCTAGAGGCGAGCGAGCA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPL
MLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV

Sequences:

>Translated_158_residues
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPL
MLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
>Mature_157_residues
SNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATARIAGIQAAKKTSDLIPLCHPLM
LTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=154, Percent_Identity=80.5194805194805, Blast_Score=255, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI32566331, Length=155, Percent_Identity=40, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=50.6756756756757, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.8248175182482, Blast_Score=135, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17179; Mature: 17048

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATAR
CCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
IAGIQAAKKTSDLIPLCHPLMLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAA
HHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNVFTHINADGNAHMVDVTEKAVTEREARAEAFIEMASTTLEMIMSGSHHKGDVFATAR
CCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHH
IAGIQAAKKTSDLIPLCHPLMLTKVEVDLEAQPEHNRVRITSLCKLSGKTGVEMEALTAA
HHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCCCCCEEEEEHEEEECCCCCCCHHHHHHH
SVAALTIYDMCKAVQKDMVISQVRLLEKRGGKSGHFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]