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The map label for this gene is moaA

Identifier: 120597074

GI number: 120597074

Start: 268529

End: 269542

Strand: Direct

Name: moaA

Synonym: Sputw3181_0243

Alternate gene names: 120597074

Gene position: 268529-269542 (Clockwise)

Preceding gene: 120597071

Following gene: 120597075

Centisome position: 5.7

GC content: 45.46

Gene sequence:

>1014_bases
ATGCTCTCACCTCCCACACTTGGAAAGGTGATCATGTCTCAATTACAAGACAGCTTTGGTCGAAAATTTCACTATTTACG
GATGTCTGTTACAGACGTTTGTAACTTCAAATGCAGCTACTGTCTCCCCGATGGTTATCATCCTGATGGTAAACCAAAAT
TCTTATCTCTTAATGAGATAGAAAACCTCGTGTCTGCATTTAGCCAAGTGGGTACTCAAAAAATCCGCATAACGGGCGGT
GAGCCTACCCTACGTAAAGATTTTACCGACATTATTCGTGTTGTGGCCGATAACCCGCGCATTCACACTGTTGCGACTAC
CACTAATGGGTATAGACTCGAAAAGCATGCCAAAGAATGGTTCGATGCGGGCTTACGTCGTATTAATGTGTCCGTTGACA
GCTTAGATCCCAAAATGTTTTACCAGATCACGGGCGAAAATAAATTCGATGAAGTGATGCGGGGGATTGATGCTGCTTTA
TCGGCAGGTTTCGAGCGAGTAAAAATTAATGCCGTACTGCTTAAAGGCTTAAACGATAAAGATTTACCGCGATTTTTACA
CTGGATTAAACACACGCCAATTGACCTACGCTTTATCGAGCTGATGGAAACGGGTTTGGGTCGTGAGTATTTTCAGGCCC
ACCATTTAGCGGGTGCCGATATTAAGGCGCAATTATTGGCCGATGGTTGGCAATTTGATACGCCAAGCGCCTCCGATGGT
CCTGCGCAAAACTTTAGTCACTCGGATTATAAGGGGCGTATTGGCTTGATCATGCCCTATGCCAATAATTTCTGCGCTAC
CTGTAATCGTTTACGCGTATCGGCAAAGGGGAAATTGCATTTATGCCTCTTTACCGAGTCCGGTGTCGATTTGCGTGATC
TACTGCAGCATGCTGATCAGCAAGCGGAATTAATCGAACGCCTGCACGGCCAATTAGCCCAGAAGAAAGAAACCCATTAC
TTGCATCAAGGCATCACTGGTGTCACTCAGCATCTTGCCTCTATTGGTGGCTAG

Upstream 100 bases:

>100_bases
GGCTTATAATCACCAGCGACGGTTCTCCGAGCTTGCCTACCTACGTCAATAGATATGGAGGTGTAGCCGTGGTAATAATG
CCACCGGGGTGAGTAAAGAA

Downstream 100 bases:

>100_bases
ATCTGTATTTAGGTGTTTTGTCATCGCTAATGTAGCGCGAGTATAAGCCCAATTTTCCTTGCACTTTGTTTTGACCTCAC
ATGAAAGGATCGCTCCAATG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLSPPTLGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGKPKFLSLNEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAKEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKINAVLLKGLNDKDLPRFLHWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLLADGWQFDTPSASDG
PAQNFSHSDYKGRIGLIMPYANNFCATCNRLRVSAKGKLHLCLFTESGVDLRDLLQHADQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG

Sequences:

>Translated_337_residues
MLSPPTLGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGKPKFLSLNEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAKEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKINAVLLKGLNDKDLPRFLHWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLLADGWQFDTPSASDG
PAQNFSHSDYKGRIGLIMPYANNFCATCNRLRVSAKGKLHLCLFTESGVDLRDLLQHADQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG
>Mature_337_residues
MLSPPTLGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGKPKFLSLNEIENLVSAFSQVGTQKIRITGG
EPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAKEWFDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAAL
SAGFERVKINAVLLKGLNDKDLPRFLHWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLLADGWQFDTPSASDG
PAQNFSHSDYKGRIGLIMPYANNFCATCNRLRVSAKGKLHLCLFTESGVDLRDLLQHADQQAELIERLHGQLAQKKETHY
LHQGITGVTQHLASIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=308, Percent_Identity=35.7142857142857, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI22027536, Length=310, Percent_Identity=36.1290322580645, Blast_Score=198, Evalue=6e-51,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=58.6626139817629, Blast_Score=413, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI32566331, Length=307, Percent_Identity=37.4592833876222, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI32566329, Length=307, Percent_Identity=37.4592833876222, Blast_Score=203, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17561210, Length=307, Percent_Identity=37.1335504885993, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI28574488, Length=322, Percent_Identity=34.1614906832298, Blast_Score=195, Evalue=3e-50,
Organism=Drosophila melanogaster, GI28574490, Length=312, Percent_Identity=34.2948717948718, Blast_Score=193, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37881; Mature: 37881

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPPTLGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGKPKFLSLNEI
CCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCEEEEECCCCCCCCCCCCEEEHHHH
ENLVSAFSQVGTQKIRITGGEPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAKEW
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHH
FDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAALSAGFERVKINAVLLKGLNDK
HHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEEEEEECCCCC
DLPRFLHWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLLADGWQFDTPSASDG
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCC
PAQNFSHSDYKGRIGLIMPYANNFCATCNRLRVSAKGKLHLCLFTESGVDLRDLLQHADQ
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHHHCCH
QAELIERLHGQLAQKKETHYLHQGITGVTQHLASIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSPPTLGKVIMSQLQDSFGRKFHYLRMSVTDVCNFKCSYCLPDGYHPDGKPKFLSLNEI
CCCCCHHHHHHHHHHHHHHCCEEEEEEEEHHHHHCCEEEEECCCCCCCCCCCCEEEHHHH
ENLVSAFSQVGTQKIRITGGEPTLRKDFTDIIRVVADNPRIHTVATTTNGYRLEKHAKEW
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHH
FDAGLRRINVSVDSLDPKMFYQITGENKFDEVMRGIDAALSAGFERVKINAVLLKGLNDK
HHHHHHEEEEEHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHEEEEEEEEECCCCC
DLPRFLHWIKHTPIDLRFIELMETGLGREYFQAHHLAGADIKAQLLADGWQFDTPSASDG
CHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCC
PAQNFSHSDYKGRIGLIMPYANNFCATCNRLRVSAKGKLHLCLFTESGVDLRDLLQHADQ
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHEEEECCCCEEEEEEECCCCCHHHHHHHCCH
QAELIERLHGQLAQKKETHYLHQGITGVTQHLASIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA