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The map label for this gene is comF [H]

Identifier: 120596946

GI number: 120596946

Start: 139833

End: 140621

Strand: Direct

Name: comF [H]

Synonym: Sputw3181_0113

Alternate gene names: 120596946

Gene position: 139833-140621 (Clockwise)

Preceding gene: 120596943

Following gene: 120596947

Centisome position: 2.97

GC content: 48.92

Gene sequence:

>789_bases
ATGCCGCACATTGTCAAAGGGATTTGGCCGCAATCTGCTTTGCGGATAATGCGTCTAGGATATCAACTCTGCATAACTTG
GTTGGCGGGCAGTTTACCTAACCGTTGTCTTCTGTGCCACCAATCCATGCAAGCACCAGAAACGGGGATTTGTATGGTTT
GCCTACAAACGGGTCTATACCATAGTCCCATTTGTCTTGGTTGTGGCAGGTCAATGCTGCTTGAAATGGATTATTGCGGT
GCATGCCAAAAATATTCACCCCATAAGATCATTGCCCCCTGCAGTTATCACCAAGGTTTAGGGACTTGGGTTGGTGCAAT
TAAGTACCAAGGTCAACTTGCGGCATTGCCCGTACTCTGTCGTGCCTTGGTTGCGCGAATTAACCACCTTGAGCAGTTGG
GCTTATTAACGCTTCCCCAAGCGATAGTACCAGTGCCATTGCACCCCAAACGCTTACAGCAAAGAGGGTTTAATCAGGCT
TGGTTGATTGCCCATGAGTTGTCTCAACGCTTACAGTTGCCCTTAGTTGACCAAGGATTAACGCGGCGACAGGATACCCG
TCCGCAGGCTGGATTGAACGGTGCGCAGCGGCGGCGGAATCTACAGGATGCATTTATGTTAGATGACGACTTTGTTTATC
AGCGTATTGCACTGGTAGATGATGTCGTCACAACGGGGACCACAGTCGCTGAAATTGCCCGTTTATTTGAAGCGCGATAC
GTGCATGTTCAAATATGGTGTCTTGCACGAGCCGAAGCGCCAGGTTTGTTGGATACAACGGACTTATAA

Upstream 100 bases:

>100_bases
CAGATCTGGCCCTTTGCCTCTGGTTTCAATATGCAAATTTACTGGGTTTGTGGGAATCACTTGGCTCACTTGAGTGCCTC
TAAATGGATTAGGTGGATAT

Downstream 100 bases:

>100_bases
AACAGATCGCGGTAGTTTAGCGTTACGAACGTCAAAACTATGTCAAAAACACGGGGTATAAAAAATAAGTTTTAATTTTG
CGATCAAATGTAAGTATATG

Product: competence protein ComF

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPHIVKGIWPQSALRIMRLGYQLCITWLAGSLPNRCLLCHQSMQAPETGICMVCLQTGLYHSPICLGCGRSMLLEMDYCG
ACQKYSPHKIIAPCSYHQGLGTWVGAIKYQGQLAALPVLCRALVARINHLEQLGLLTLPQAIVPVPLHPKRLQQRGFNQA
WLIAHELSQRLQLPLVDQGLTRRQDTRPQAGLNGAQRRRNLQDAFMLDDDFVYQRIALVDDVVTTGTTVAEIARLFEARY
VHVQIWCLARAEAPGLLDTTDL

Sequences:

>Translated_262_residues
MPHIVKGIWPQSALRIMRLGYQLCITWLAGSLPNRCLLCHQSMQAPETGICMVCLQTGLYHSPICLGCGRSMLLEMDYCG
ACQKYSPHKIIAPCSYHQGLGTWVGAIKYQGQLAALPVLCRALVARINHLEQLGLLTLPQAIVPVPLHPKRLQQRGFNQA
WLIAHELSQRLQLPLVDQGLTRRQDTRPQAGLNGAQRRRNLQDAFMLDDDFVYQRIALVDDVVTTGTTVAEIARLFEARY
VHVQIWCLARAEAPGLLDTTDL
>Mature_261_residues
PHIVKGIWPQSALRIMRLGYQLCITWLAGSLPNRCLLCHQSMQAPETGICMVCLQTGLYHSPICLGCGRSMLLEMDYCGA
CQKYSPHKIIAPCSYHQGLGTWVGAIKYQGQLAALPVLCRALVARINHLEQLGLLTLPQAIVPVPLHPKRLQQRGFNQAW
LIAHELSQRLQLPLVDQGLTRRQDTRPQAGLNGAQRRRNLQDAFMLDDDFVYQRIALVDDVVTTGTTVAEIARLFEARYV
HVQIWCLARAEAPGLLDTTDL

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=224, Percent_Identity=33.0357142857143, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 29314; Mature: 29183

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIVKGIWPQSALRIMRLGYQLCITWLAGSLPNRCLLCHQSMQAPETGICMVCLQTGLY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCC
HSPICLGCGRSMLLEMDYCGACQKYSPHKIIAPCSYHQGLGTWVGAIKYQGQLAALPVLC
CCCHHHHCCCHHEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RALVARINHLEQLGLLTLPQAIVPVPLHPKRLQQRGFNQAWLIAHELSQRLQLPLVDQGL
HHHHHHHHHHHHHCHHHCCHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
TRRQDTRPQAGLNGAQRRRNLQDAFMLDDDFVYQRIALVDDVVTTGTTVAEIARLFEARY
HHCCCCCCCCCCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHE
VHVQIWCLARAEAPGLLDTTDL
EEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PHIVKGIWPQSALRIMRLGYQLCITWLAGSLPNRCLLCHQSMQAPETGICMVCLQTGLY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCC
HSPICLGCGRSMLLEMDYCGACQKYSPHKIIAPCSYHQGLGTWVGAIKYQGQLAALPVLC
CCCHHHHCCCHHEEECCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHH
RALVARINHLEQLGLLTLPQAIVPVPLHPKRLQQRGFNQAWLIAHELSQRLQLPLVDQGL
HHHHHHHHHHHHHCHHHCCHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
TRRQDTRPQAGLNGAQRRRNLQDAFMLDDDFVYQRIALVDDVVTTGTTVAEIARLFEARY
HHCCCCCCCCCCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHE
VHVQIWCLARAEAPGLLDTTDL
EEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]