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The map label for this gene is fhuE [H]

Identifier: 120596923

GI number: 120596923

Start: 110012

End: 112213

Strand: Direct

Name: fhuE [H]

Synonym: Sputw3181_0090

Alternate gene names: 120596923

Gene position: 110012-112213 (Clockwise)

Preceding gene: 120596922

Following gene: 120596930

Centisome position: 2.34

GC content: 44.37

Gene sequence:

>2202_bases
GTGTTACCGTATGCGTATCCTAAAGACACTACTGAAATGACTATGCGCTTCAATCTACTTCCTCTCGCTGCAGCTATTAC
TTTGGCGTTAAATCCTCTGTCCGTTTTGGCTGGGGAGCAATCTTCTACAGAAACAAAAGATCAGAATATCGAAAAAATTA
CTGTGATGGGTAAATATACCGTCAGTAGAACCATTGACACTGCCACAGGTTTGGGGCTGTCACTGCAGGAAACTCCGCAG
TCTGTCAGTATTATGACGGCTGAGCGGATTCAAGATCAGGCACTCAATACCGTTGTCGATGTTGTTAACAATACCGTAGG
TTTATCTTCCTCTAAAACAGATAACGTCCGAAATGGTTTTATGGCCCGTGGTTTTGCGGTGCAGAATTACCAGATAGACG
GTGTGCCATTGTCTTGGAGTTTAGGCGGTGATGCGGGTGAGACAGTATCCGATATTTCCTTATATGAACGCGTTGAAGTC
GTTCGTGGTGCCACAGGATTATTGACGGGTGCAGGAGATCCTTCCGCGTCTATTAACCTAGTGCGCAAACATGCCGATAG
TGCCGAGCTTAAGGGCTATGTTGATGTTGCTACGGGTAGCTGGGATAAAAAACAAATTACAGCGGATGTTTCCAATGGCC
TTAACGACAGTGGCAGTGTGCGTGGTCGTATGGTGGCTAAATATGTCAATAGCGATTCCTATCAGGATCTTTATCAAGAT
CGTAAGACCATTCTTTATGGTGTAGTGGATTCAGACATCACTGAAAACACTATGCTGCGCGTCGGCGGTAGTTACAATAA
CAATAACCCCAAAGGAGCGATGTGGGGCGCCTTACCCGCAATGTTCAGCGATGGTTCTGCGACAGATTGGGATGTTTCTG
CCACAACGGCCGCAGACTGGAGTCGTTGGGAAACCACCAACATCAACTATTTTGCTAATTTGAATCATTATTTCAGTAAT
GGTTGGCAATTGGTGGCGAACTATAATCGCATGGAATACGAAACTACCACCAAAATGATCTATATGTCCGGTTTGCTGGA
TAAAGAAACCGGTGCAGGATTAAGTGGTCAGCGTTATCACAGCCATGGTGAAAGTAACTCCGATAATTTTGATTTCCAAT
TGAAAGGGGATTACCAGCTCTTTAACCGTGAGCATCAATTTGTGGCAGGGGCTTTGTACAGCAAACAGAAATCCTATGCT
GATACCTATGAGCCTATCCGTGAAGACATGACGGGTTGGGACTCAAAGGTGGTTGAAAACTTTTATGATTGGCGCAGTAA
CACCTTCGATGAGCCGCAGTGGTCAACGGACGCTAATCGTCAGTTAAATATGGATACTGAACAGAAAGGTTTCTACGCGG
CAACTCGGCTGACGATTACCGATGATTTTAAAATCATTGCTGGTGGTCGTATTTCTAGCTGGAATCGTGAAGGGGTCAGC
TATGGTACTAGCACTAATTTTGGTGATGATGGTGTATTTGTACCTTATGTTGGCGCACTGTATGACATTAACGAAGAGCA
TCGGGTTTACGCCAGTTATACTGAAATATTTAATCCGCAGAATGTGACTAATGCCTACGGAGAATATATAGATCCCTTAA
AAGGCAAAGCCTATGAAGTGGGTTTGAAGAGCGCTTATTTGGACGATCGTCTACATACTACAGTAGCGCTGTTCAAAATT
GATCAGGACAATCTGGCAACGCCAGATGGAACTGTCACCATTGACGGCAAACCAGTGACTAATTACAAGGCTGCTCAAGG
TACTGAAAGTACTGGCTTTGAGTTAGAAGTTGTGGGTGAATTTATTGATGGCTGGAATATTTCGGCTGGTTATTCTCAAT
TCACCGCTGAAGATGCCGAAGGCAGTAAAGTGGAGACCACGAGCCCTCGTAAACAGTTTAAACTCTTTACTACCTATCAG
TTTGTTGACCATTTACCTGAGTTGACCGTGGGTGGTGGTGTTAACTGGCAGAGCGACAGTTACTCGCAGAGCGGTGGCGT
TGTCATTGAGCAGGAGGCATATTCGCTTGTTAACCTGATGGCTCGTTATAATCTAGCGGAAAATATGGATCTGCAACTGA
ACCTCGAAAACCTGCTGGATGAAAAATACTATGCCTATATGTCAGCTTCTGGACTTTCATACAGCATATATCACTATGGT
ACCCCTAGAAATGTAACTGTTAGTTTTAACTATCGTTTCTAA

Upstream 100 bases:

>100_bases
TCAATCCTTAAATATCTCCCATCATGCTTTAACTGCTACTGAATCGTGGCAGGTTTGTTATCTATATCACACAAAATACA
AATGAAAACTATTCGTAATA

Downstream 100 bases:

>100_bases
GGTTTACTTGCTGCAAACTGGTGGTCACCTAAGGTTGACCACCAGTCCTCATTTTTACCCATTTGCAATTAGCTAACATT
AAGATTTATGGTAAGAGTTA

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MLPYAYPKDTTEMTMRFNLLPLAAAITLALNPLSVLAGEQSSTETKDQNIEKITVMGKYTVSRTIDTATGLGLSLQETPQ
SVSIMTAERIQDQALNTVVDVVNNTVGLSSSKTDNVRNGFMARGFAVQNYQIDGVPLSWSLGGDAGETVSDISLYERVEV
VRGATGLLTGAGDPSASINLVRKHADSAELKGYVDVATGSWDKKQITADVSNGLNDSGSVRGRMVAKYVNSDSYQDLYQD
RKTILYGVVDSDITENTMLRVGGSYNNNNPKGAMWGALPAMFSDGSATDWDVSATTAADWSRWETTNINYFANLNHYFSN
GWQLVANYNRMEYETTTKMIYMSGLLDKETGAGLSGQRYHSHGESNSDNFDFQLKGDYQLFNREHQFVAGALYSKQKSYA
DTYEPIREDMTGWDSKVVENFYDWRSNTFDEPQWSTDANRQLNMDTEQKGFYAATRLTITDDFKIIAGGRISSWNREGVS
YGTSTNFGDDGVFVPYVGALYDINEEHRVYASYTEIFNPQNVTNAYGEYIDPLKGKAYEVGLKSAYLDDRLHTTVALFKI
DQDNLATPDGTVTIDGKPVTNYKAAQGTESTGFELEVVGEFIDGWNISAGYSQFTAEDAEGSKVETTSPRKQFKLFTTYQ
FVDHLPELTVGGGVNWQSDSYSQSGGVVIEQEAYSLVNLMARYNLAENMDLQLNLENLLDEKYYAYMSASGLSYSIYHYG
TPRNVTVSFNYRF

Sequences:

>Translated_733_residues
MLPYAYPKDTTEMTMRFNLLPLAAAITLALNPLSVLAGEQSSTETKDQNIEKITVMGKYTVSRTIDTATGLGLSLQETPQ
SVSIMTAERIQDQALNTVVDVVNNTVGLSSSKTDNVRNGFMARGFAVQNYQIDGVPLSWSLGGDAGETVSDISLYERVEV
VRGATGLLTGAGDPSASINLVRKHADSAELKGYVDVATGSWDKKQITADVSNGLNDSGSVRGRMVAKYVNSDSYQDLYQD
RKTILYGVVDSDITENTMLRVGGSYNNNNPKGAMWGALPAMFSDGSATDWDVSATTAADWSRWETTNINYFANLNHYFSN
GWQLVANYNRMEYETTTKMIYMSGLLDKETGAGLSGQRYHSHGESNSDNFDFQLKGDYQLFNREHQFVAGALYSKQKSYA
DTYEPIREDMTGWDSKVVENFYDWRSNTFDEPQWSTDANRQLNMDTEQKGFYAATRLTITDDFKIIAGGRISSWNREGVS
YGTSTNFGDDGVFVPYVGALYDINEEHRVYASYTEIFNPQNVTNAYGEYIDPLKGKAYEVGLKSAYLDDRLHTTVALFKI
DQDNLATPDGTVTIDGKPVTNYKAAQGTESTGFELEVVGEFIDGWNISAGYSQFTAEDAEGSKVETTSPRKQFKLFTTYQ
FVDHLPELTVGGGVNWQSDSYSQSGGVVIEQEAYSLVNLMARYNLAENMDLQLNLENLLDEKYYAYMSASGLSYSIYHYG
TPRNVTVSFNYRF
>Mature_733_residues
MLPYAYPKDTTEMTMRFNLLPLAAAITLALNPLSVLAGEQSSTETKDQNIEKITVMGKYTVSRTIDTATGLGLSLQETPQ
SVSIMTAERIQDQALNTVVDVVNNTVGLSSSKTDNVRNGFMARGFAVQNYQIDGVPLSWSLGGDAGETVSDISLYERVEV
VRGATGLLTGAGDPSASINLVRKHADSAELKGYVDVATGSWDKKQITADVSNGLNDSGSVRGRMVAKYVNSDSYQDLYQD
RKTILYGVVDSDITENTMLRVGGSYNNNNPKGAMWGALPAMFSDGSATDWDVSATTAADWSRWETTNINYFANLNHYFSN
GWQLVANYNRMEYETTTKMIYMSGLLDKETGAGLSGQRYHSHGESNSDNFDFQLKGDYQLFNREHQFVAGALYSKQKSYA
DTYEPIREDMTGWDSKVVENFYDWRSNTFDEPQWSTDANRQLNMDTEQKGFYAATRLTITDDFKIIAGGRISSWNREGVS
YGTSTNFGDDGVFVPYVGALYDINEEHRVYASYTEIFNPQNVTNAYGEYIDPLKGKAYEVGLKSAYLDDRLHTTVALFKI
DQDNLATPDGTVTIDGKPVTNYKAAQGTESTGFELEVVGEFIDGWNISAGYSQFTAEDAEGSKVETTSPRKQFKLFTTYQ
FVDHLPELTVGGGVNWQSDSYSQSGGVVIEQEAYSLVNLMARYNLAENMDLQLNLENLLDEKYYAYMSASGLSYSIYHYG
TPRNVTVSFNYRF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=739, Percent_Identity=36.8064952638701, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1786344, Length=779, Percent_Identity=23.7483953786906, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI1787024, Length=340, Percent_Identity=27.3529411764706, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81442; Mature: 81442

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPYAYPKDTTEMTMRFNLLPLAAAITLALNPLSVLAGEQSSTETKDQNIEKITVMGKYT
CCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEE
VSRTIDTATGLGLSLQETPQSVSIMTAERIQDQALNTVVDVVNNTVGLSSSKTDNVRNGF
EEEEEHHHHCCCCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCC
MARGFAVQNYQIDGVPLSWSLGGDAGETVSDISLYERVEVVRGATGLLTGAGDPSASINL
EECCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
VRKHADSAELKGYVDVATGSWDKKQITADVSNGLNDSGSVRGRMVAKYVNSDSYQDLYQD
EECCCCCCCCCEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEEEEHHCCCCHHHHHHC
RKTILYGVVDSDITENTMLRVGGSYNNNNPKGAMWGALPAMFSDGSATDWDVSATTAADW
CCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCC
SRWETTNINYFANLNHYFSNGWQLVANYNRMEYETTTKMIYMSGLLDKETGAGLSGQRYH
CCEEECCEEEEECCCHHHCCCEEEEECCCCEEEEHHHEEEEEECCCCCCCCCCCCCCHHH
SHGESNSDNFDFQLKGDYQLFNREHQFVAGALYSKQKSYADTYEPIREDMTGWDSKVVEN
CCCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FYDWRSNTFDEPQWSTDANRQLNMDTEQKGFYAATRLTITDDFKIIAGGRISSWNREGVS
HHHHCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEEEECCEEEEECCEECCCCCCCCC
YGTSTNFGDDGVFVPYVGALYDINEEHRVYASYTEIFNPQNVTNAYGEYIDPLKGKAYEV
CCCCCCCCCCCEECCCCCEEEECCCCCEEEEEHHHHCCCCCHHHHHHHHCCCCCCCEEEE
GLKSAYLDDRLHTTVALFKIDQDNLATPDGTVTIDGKPVTNYKAAQGTESTGFELEVVGE
CCHHHHHCCHHEEEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEH
FIDGWNISAGYSQFTAEDAEGSKVETTSPRKQFKLFTTYQFVDHLPELTVGGGVNWQSDS
HHCCCCCCCCCCCCCCCCCCCCEEECCCCHHHEEEEHHHHHHHCCCCEEECCCCCCCCCC
YSQSGGVVIEQEAYSLVNLMARYNLAENMDLQLNLENLLDEKYYAYMSASGLSYSIYHYG
CCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCHHHEEEEECCCCEEEEEEEC
TPRNVTVSFNYRF
CCCEEEEEEEECC
>Mature Secondary Structure
MLPYAYPKDTTEMTMRFNLLPLAAAITLALNPLSVLAGEQSSTETKDQNIEKITVMGKYT
CCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEEEEEEE
VSRTIDTATGLGLSLQETPQSVSIMTAERIQDQALNTVVDVVNNTVGLSSSKTDNVRNGF
EEEEEHHHHCCCCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCC
MARGFAVQNYQIDGVPLSWSLGGDAGETVSDISLYERVEVVRGATGLLTGAGDPSASINL
EECCEEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
VRKHADSAELKGYVDVATGSWDKKQITADVSNGLNDSGSVRGRMVAKYVNSDSYQDLYQD
EECCCCCCCCCEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEEEEHHCCCCHHHHHHC
RKTILYGVVDSDITENTMLRVGGSYNNNNPKGAMWGALPAMFSDGSATDWDVSATTAADW
CCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCC
SRWETTNINYFANLNHYFSNGWQLVANYNRMEYETTTKMIYMSGLLDKETGAGLSGQRYH
CCEEECCEEEEECCCHHHCCCEEEEECCCCEEEEHHHEEEEEECCCCCCCCCCCCCCHHH
SHGESNSDNFDFQLKGDYQLFNREHQFVAGALYSKQKSYADTYEPIREDMTGWDSKVVEN
CCCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FYDWRSNTFDEPQWSTDANRQLNMDTEQKGFYAATRLTITDDFKIIAGGRISSWNREGVS
HHHHCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEEEECCEEEEECCEECCCCCCCCC
YGTSTNFGDDGVFVPYVGALYDINEEHRVYASYTEIFNPQNVTNAYGEYIDPLKGKAYEV
CCCCCCCCCCCEECCCCCEEEECCCCCEEEEEHHHHCCCCCHHHHHHHHCCCCCCCEEEE
GLKSAYLDDRLHTTVALFKIDQDNLATPDGTVTIDGKPVTNYKAAQGTESTGFELEVVGE
CCHHHHHCCHHEEEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEEH
FIDGWNISAGYSQFTAEDAEGSKVETTSPRKQFKLFTTYQFVDHLPELTVGGGVNWQSDS
HHCCCCCCCCCCCCCCCCCCCCEEECCCCHHHEEEEHHHHHHHCCCCEEECCCCCCCCCC
YSQSGGVVIEQEAYSLVNLMARYNLAENMDLQLNLENLLDEKYYAYMSASGLSYSIYHYG
CCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEEHHHHHCHHHEEEEECCCCEEEEEEEC
TPRNVTVSFNYRF
CCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]