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The map label for this gene is hemY [H]

Identifier: 119947241

GI number: 119947241

Start: 4453253

End: 4454443

Strand: Reverse

Name: hemY [H]

Synonym: Ping_3639

Alternate gene names: 119947241

Gene position: 4454443-4453253 (Counterclockwise)

Preceding gene: 119947242

Following gene: 119947240

Centisome position: 97.69

GC content: 38.87

Gene sequence:

>1191_bases
ATGATTCGAATTATTATAGTCATTGCAGCACTGATCGCCGGATTATTTTTTGGTCCTGAAATTAGCAGTAATAAGGGTTA
TATTTTAATTTCTCTTGATAACTATACCACCTATGAAACAACGATTATTAATGCGCTTATTGCGACCGTTGTCTTTTATT
TTTTATTAGGATTAATTGAATGGATTTTACGTAAATTACTTTCAATGAGCTCTATTACTCGTGGTTGGTTCGGTCAGCGT
AAAACTAGAAAAGCACAAAGAAACAGTTTATTAGGTATGTTAGCGCTGCTCGAAGGTAATAGTCGACAAGCGCAAAAGTT
ATTGTCCAAATCAGCTGAGAAAACGGCAGCGCCTGCCTTAACTTATATTGCAGCAGCTAACGCTGCGCAGCAGCAAGGTG
ACTATGCATTACGTGACTCTTATCTGCAGCAGGCAACAAAAAGCCAAAAAGGCTGTAACTTAGCCGTTGGTTTGGTGTGG
ATTGAATTACAGATTGAAGCAAAACAATTTGCAGATGCTCTTATTAAGCTTAAGGAGTTGGATAGCACCTTTCCGGGTAA
TAAGCGTATTGCAAAATTGTACTTGGATATTTATCCCCCGTTAAATCAGTGGGCTGATTATATTGAGGTCTTAATCAAGC
AACGTAAGTATTTGTCCTTAGTTGATACTGAGTTTGAGGCGATTAAATTAAATGCTTATCAGCACCTTTTTAAGCAGTTA
GCCCTGCAGAGCGGCGAGGCCCTGCAGGCATTATGGAATGACAAATCATCGCGCAGCATGCGCAAAGATGTCGCTTACCA
AAGCGCAATGCTAGATGCTTTTATTGAGGGGAAATATTATGAATTTGCTGAGTATTTTTTAGGAGAAAAGCTTAAAGAGC
ATTTCAATGTCACACTACTGGCTTATGTGGACAAGATAAAGATTATGGATAACAACAAGCTGATTTTAATCCTGGAAAAG
CAACTTAAAAAAGATCCGGAAAATGGGGCTATTCATCATGCGCTCGCGAAGCTAAAATTAAATGAAGACAACGAATCAGC
AGCGATCGAGCATTTGCAAAAAGGGGTCGAACTGGATCCTAATGTCGACGATTTTGCGCTACTGGCCAAAATACTGGAAA
AAGCGGATCGCCTCGATGAAGCTAATAATTATTACCGCAAAGGCTTGTTATTATTTATGTCATCAAAATAA

Upstream 100 bases:

>100_bases
TACCCCGATCAGTTAAAAAGCGCAACTGTACTGGCGCGTATAATGACACAGCGGGTAAACAAATCACTCGCTAATTCGAC
TGAAGAATAGGGAGAATATT

Downstream 100 bases:

>100_bases
AATATTGATATCATAAATTATAAATAGAGCAAGGTCAGATTTCTGACTCTTAAAGCAGTTCGAGTATAGTCAAAGCAGAG
CCTCTTCTGCTTTTTTTACA

Product: HemY domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIRIIIVIAALIAGLFFGPEISSNKGYILISLDNYTTYETTIINALIATVVFYFLLGLIEWILRKLLSMSSITRGWFGQR
KTRKAQRNSLLGMLALLEGNSRQAQKLLSKSAEKTAAPALTYIAAANAAQQQGDYALRDSYLQQATKSQKGCNLAVGLVW
IELQIEAKQFADALIKLKELDSTFPGNKRIAKLYLDIYPPLNQWADYIEVLIKQRKYLSLVDTEFEAIKLNAYQHLFKQL
ALQSGEALQALWNDKSSRSMRKDVAYQSAMLDAFIEGKYYEFAEYFLGEKLKEHFNVTLLAYVDKIKIMDNNKLILILEK
QLKKDPENGAIHHALAKLKLNEDNESAAIEHLQKGVELDPNVDDFALLAKILEKADRLDEANNYYRKGLLLFMSSK

Sequences:

>Translated_396_residues
MIRIIIVIAALIAGLFFGPEISSNKGYILISLDNYTTYETTIINALIATVVFYFLLGLIEWILRKLLSMSSITRGWFGQR
KTRKAQRNSLLGMLALLEGNSRQAQKLLSKSAEKTAAPALTYIAAANAAQQQGDYALRDSYLQQATKSQKGCNLAVGLVW
IELQIEAKQFADALIKLKELDSTFPGNKRIAKLYLDIYPPLNQWADYIEVLIKQRKYLSLVDTEFEAIKLNAYQHLFKQL
ALQSGEALQALWNDKSSRSMRKDVAYQSAMLDAFIEGKYYEFAEYFLGEKLKEHFNVTLLAYVDKIKIMDNNKLILILEK
QLKKDPENGAIHHALAKLKLNEDNESAAIEHLQKGVELDPNVDDFALLAKILEKADRLDEANNYYRKGLLLFMSSK
>Mature_396_residues
MIRIIIVIAALIAGLFFGPEISSNKGYILISLDNYTTYETTIINALIATVVFYFLLGLIEWILRKLLSMSSITRGWFGQR
KTRKAQRNSLLGMLALLEGNSRQAQKLLSKSAEKTAAPALTYIAAANAAQQQGDYALRDSYLQQATKSQKGCNLAVGLVW
IELQIEAKQFADALIKLKELDSTFPGNKRIAKLYLDIYPPLNQWADYIEVLIKQRKYLSLVDTEFEAIKLNAYQHLFKQL
ALQSGEALQALWNDKSSRSMRKDVAYQSAMLDAFIEGKYYEFAEYFLGEKLKEHFNVTLLAYVDKIKIMDNNKLILILEK
QLKKDPENGAIHHALAKLKLNEDNESAAIEHLQKGVELDPNVDDFALLAKILEKADRLDEANNYYRKGLLLFMSSK

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=386, Percent_Identity=27.720207253886, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 44933; Mature: 44933

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIIIVIAALIAGLFFGPEISSNKGYILISLDNYTTYETTIINALIATVVFYFLLGLIE
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
WILRKLLSMSSITRGWFGQRKTRKAQRNSLLGMLALLEGNSRQAQKLLSKSAEKTAAPAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TYIAAANAAQQQGDYALRDSYLQQATKSQKGCNLAVGLVWIELQIEAKQFADALIKLKEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHH
DSTFPGNKRIAKLYLDIYPPLNQWADYIEVLIKQRKYLSLVDTEFEAIKLNAYQHLFKQL
CCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHH
ALQSGEALQALWNDKSSRSMRKDVAYQSAMLDAFIEGKYYEFAEYFLGEKLKEHFNVTLL
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEE
AYVDKIKIMDNNKLILILEKQLKKDPENGAIHHALAKLKLNEDNESAAIEHLQKGVELDP
EEEEEEEEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHEECCCCHHHHHHHHHCCCCCCC
NVDDFALLAKILEKADRLDEANNYYRKGLLLFMSSK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MIRIIIVIAALIAGLFFGPEISSNKGYILISLDNYTTYETTIINALIATVVFYFLLGLIE
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
WILRKLLSMSSITRGWFGQRKTRKAQRNSLLGMLALLEGNSRQAQKLLSKSAEKTAAPAL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TYIAAANAAQQQGDYALRDSYLQQATKSQKGCNLAVGLVWIELQIEAKQFADALIKLKEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECHHHHHHHHHHHHHH
DSTFPGNKRIAKLYLDIYPPLNQWADYIEVLIKQRKYLSLVDTEFEAIKLNAYQHLFKQL
CCCCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHH
ALQSGEALQALWNDKSSRSMRKDVAYQSAMLDAFIEGKYYEFAEYFLGEKLKEHFNVTLL
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEE
AYVDKIKIMDNNKLILILEKQLKKDPENGAIHHALAKLKLNEDNESAAIEHLQKGVELDP
EEEEEEEEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHEECCCCHHHHHHHHHCCCCCCC
NVDDFALLAKILEKADRLDEANNYYRKGLLLFMSSK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]