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The map label for this gene is hemX [H]

Identifier: 119947242

GI number: 119947242

Start: 4454454

End: 4455596

Strand: Reverse

Name: hemX [H]

Synonym: Ping_3640

Alternate gene names: 119947242

Gene position: 4455596-4454454 (Counterclockwise)

Preceding gene: 119947243

Following gene: 119947241

Centisome position: 97.72

GC content: 39.72

Gene sequence:

>1143_bases
ATGACCAAGAGTAATAATGATAATGATAATGAAGAAATAATCGATAATGAGGAGCTCAAATCTGACCTTTCGGCTGCTGA
ATCAGAAAATATCCCCGTCAATAAAAACCCTAAAAGCAGCAAATCAGCGCTGGTTATTGCTTTATTAGCCCTGTTTCTGA
TTGTTACTTTAATTTTATCAGCAGGTTATTTTTATAAACTGAATAAAACGCTAACGGATCAGCAGCAAGCCAAAATGGCT
CAGTTGAGTAGCAGTTTATCTTCTCAGGAAGCCACCCTTAATCAACAAAATGCAACGTTAGAGTCGGCATTAGTGCAGGT
TAATCAGCAACTTCGACAAGTGAAAAATCAAAATAAGCTTTATAGCAGCGATCTGCAGTCTTTACAGCGCCGCATGGCAG
AAACAACAGTGCGTCACCCAAATGATTGGATTCTGGCTGAAGTGGAATACCTAATACGTTTAGCGGGCAGTAAAATTTGG
TTAGAAAGTGATCTGGCAACAGCCGTTGCGCTTCTTAGCGCTGCTGATCAGCGTCTGCTGGTATTAAGCGATCCTAGTCT
TAATCCATTGCGCTCTGCATTATTAGAAGATATTAACAGTTTAGAATCTTTACCGAAACGCGATCCTGATGGTCTGATTT
TAGCGCTTTCTAACCTTGAAAGTAGGGCGGATAAACTGCTGGTGGTGGGGTTAAATTTATCAACACCGGACAGCAAAGAT
AAAAGTGAAGTTTCAACTGATATTAAAGATTGGAATGAAAACTTATCCAAATCATGGCGCAGTTTTGTTGAGAGTTTTGT
GGTTATCAATAAACGTGATGTGAAAGTACAAGCGTTACTCTCTTCGGAGCAAAAGTGGTATTTACAGGAGAATTTACGCG
CGGAGCTCGCTAAGGCTGAGTTTGCAGTTTACCGTGAGCAGCAAGATATTTATGACATAGCGATGCAAACTGCGTCTGAT
TTATTAACTGATTATTATGATTTAACCGATAATACCACCAACTACTTTTTCAAATCTATTCAGAGTTTAAGAGATAAAAA
GGTGTCCGTTGATTACCCCGATCAGTTAAAAAGCGCAACTGTACTGGCGCGTATAATGACACAGCGGGTAAACAAATCAC
TCGCTAATTCGACTGAAGAATAG

Upstream 100 bases:

>100_bases
TCTGATCAGCAAGTGATTGATTATTTTAAACATTAGTAAAAAAAGATAGTCATGTATATTAGTAATTAAACCTTTTTGAC
TAAAAAATGTGAGGGTGGTT

Downstream 100 bases:

>100_bases
GGAGAATATTATGATTCGAATTATTATAGTCATTGCAGCACTGATCGCCGGATTATTTTTTGGTCCTGAAATTAGCAGTA
ATAAGGGTTATATTTTAATT

Product: uroporphyrin-III C-methyltransferase HemX

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTKSNNDNDNEEIIDNEELKSDLSAAESENIPVNKNPKSSKSALVIALLALFLIVTLILSAGYFYKLNKTLTDQQQAKMA
QLSSSLSSQEATLNQQNATLESALVQVNQQLRQVKNQNKLYSSDLQSLQRRMAETTVRHPNDWILAEVEYLIRLAGSKIW
LESDLATAVALLSAADQRLLVLSDPSLNPLRSALLEDINSLESLPKRDPDGLILALSNLESRADKLLVVGLNLSTPDSKD
KSEVSTDIKDWNENLSKSWRSFVESFVVINKRDVKVQALLSSEQKWYLQENLRAELAKAEFAVYREQQDIYDIAMQTASD
LLTDYYDLTDNTTNYFFKSIQSLRDKKVSVDYPDQLKSATVLARIMTQRVNKSLANSTEE

Sequences:

>Translated_380_residues
MTKSNNDNDNEEIIDNEELKSDLSAAESENIPVNKNPKSSKSALVIALLALFLIVTLILSAGYFYKLNKTLTDQQQAKMA
QLSSSLSSQEATLNQQNATLESALVQVNQQLRQVKNQNKLYSSDLQSLQRRMAETTVRHPNDWILAEVEYLIRLAGSKIW
LESDLATAVALLSAADQRLLVLSDPSLNPLRSALLEDINSLESLPKRDPDGLILALSNLESRADKLLVVGLNLSTPDSKD
KSEVSTDIKDWNENLSKSWRSFVESFVVINKRDVKVQALLSSEQKWYLQENLRAELAKAEFAVYREQQDIYDIAMQTASD
LLTDYYDLTDNTTNYFFKSIQSLRDKKVSVDYPDQLKSATVLARIMTQRVNKSLANSTEE
>Mature_379_residues
TKSNNDNDNEEIIDNEELKSDLSAAESENIPVNKNPKSSKSALVIALLALFLIVTLILSAGYFYKLNKTLTDQQQAKMAQ
LSSSLSSQEATLNQQNATLESALVQVNQQLRQVKNQNKLYSSDLQSLQRRMAETTVRHPNDWILAEVEYLIRLAGSKIWL
ESDLATAVALLSAADQRLLVLSDPSLNPLRSALLEDINSLESLPKRDPDGLILALSNLESRADKLLVVGLNLSTPDSKDK
SEVSTDIKDWNENLSKSWRSFVESFVVINKRDVKVQALLSSEQKWYLQENLRAELAKAEFAVYREQQDIYDIAMQTASDL
LTDYYDLTDNTTNYFFKSIQSLRDKKVSVDYPDQLKSATVLARIMTQRVNKSLANSTEE

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=312, Percent_Identity=34.6153846153846, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 42789; Mature: 42657

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSNNDNDNEEIIDNEELKSDLSAAESENIPVNKNPKSSKSALVIALLALFLIVTLILS
CCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
AGYFYKLNKTLTDQQQAKMAQLSSSLSSQEATLNQQNATLESALVQVNQQLRQVKNQNKL
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
YSSDLQSLQRRMAETTVRHPNDWILAEVEYLIRLAGSKIWLESDLATAVALLSAADQRLL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCEEE
VLSDPSLNPLRSALLEDINSLESLPKRDPDGLILALSNLESRADKLLVVGLNLSTPDSKD
EEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCEEEEEEECCCCCCCCC
KSEVSTDIKDWNENLSKSWRSFVESFVVINKRDVKVQALLSSEQKWYLQENLRAELAKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
FAVYREQQDIYDIAMQTASDLLTDYYDLTDNTTNYFFKSIQSLRDKKVSVDYPDQLKSAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLARIMTQRVNKSLANSTEE
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKSNNDNDNEEIIDNEELKSDLSAAESENIPVNKNPKSSKSALVIALLALFLIVTLILS
CCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
AGYFYKLNKTLTDQQQAKMAQLSSSLSSQEATLNQQNATLESALVQVNQQLRQVKNQNKL
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
YSSDLQSLQRRMAETTVRHPNDWILAEVEYLIRLAGSKIWLESDLATAVALLSAADQRLL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCEEE
VLSDPSLNPLRSALLEDINSLESLPKRDPDGLILALSNLESRADKLLVVGLNLSTPDSKD
EEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCCEEEEEEECCCCCCCCC
KSEVSTDIKDWNENLSKSWRSFVESFVVINKRDVKVQALLSSEQKWYLQENLRAELAKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
FAVYREQQDIYDIAMQTASDLLTDYYDLTDNTTNYFFKSIQSLRDKKVSVDYPDQLKSAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VLARIMTQRVNKSLANSTEE
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]