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The map label for this gene is arsR [H]

Identifier: 119947239

GI number: 119947239

Start: 4451850

End: 4452197

Strand: Reverse

Name: arsR [H]

Synonym: Ping_3637

Alternate gene names: 119947239

Gene position: 4452197-4451850 (Counterclockwise)

Preceding gene: 119947240

Following gene: 119947238

Centisome position: 97.64

GC content: 40.8

Gene sequence:

>348_bases
ATGAGCTCAACTCAATTTTTTAAGTGCCTTGCAGATGATACCCGTTTAAAAATATTGATACTTATTCAACATGAAAACGA
GCTATGTGTAGGTGAATTGATGGTGGCGTTAGATGATAGCCAAACAAAAGTCTCACGCCATCTTGCACAGCTTAGGCAAT
GTGGTTTACTGCTGGTGCGCAAGCAAAGACAGTGGGCTTATTACCGCTTAAACCCGAATTTAGCGTTTTGGATGAAAGAG
ATTATTAAGCTCACAACTGAGCACCATCCCGTTTTCCTGAATAATGCTGTCGGGAAACTTAAAAAAATGCCTGAGGGACC
GGATGGTAATAAAAACTGCTGCTCTTAA

Upstream 100 bases:

>100_bases
AAAGAGTCATTTTTTAGCCCTCTGTCATATTTCTGTCATATTTGTGCTTTAGGGTATATGTGGTATTCCACATATAAACA
GATTAATGGCATGAGGTGTT

Downstream 100 bases:

>100_bases
TAAGCATTGAATAACTGCTACTAATTACTGATAGCCGATAGCTGATAGCCGATAGCTGATAGCTGATAGCCGATAGCTGA
TAACTGACAGCTGATAACTA

Product: transcriptional regulator of ArsR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 114

Protein sequence:

>115_residues
MSSTQFFKCLADDTRLKILILIQHENELCVGELMVALDDSQTKVSRHLAQLRQCGLLLVRKQRQWAYYRLNPNLAFWMKE
IIKLTTEHHPVFLNNAVGKLKKMPEGPDGNKNCCS

Sequences:

>Translated_115_residues
MSSTQFFKCLADDTRLKILILIQHENELCVGELMVALDDSQTKVSRHLAQLRQCGLLLVRKQRQWAYYRLNPNLAFWMKE
IIKLTTEHHPVFLNNAVGKLKKMPEGPDGNKNCCS
>Mature_114_residues
SSTQFFKCLADDTRLKILILIQHENELCVGELMVALDDSQTKVSRHLAQLRQCGLLLVRKQRQWAYYRLNPNLAFWMKEI
IKLTTEHHPVFLNNAVGKLKKMPEGPDGNKNCCS

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=78, Percent_Identity=56.4102564102564, Blast_Score=90, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13285; Mature: 13154

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTQFFKCLADDTRLKILILIQHENELCVGELMVALDDSQTKVSRHLAQLRQCGLLLVR
CCCCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHEECCCHHHHHHHHHHHHHCCHHEEE
KQRQWAYYRLNPNLAFWMKEIIKLTTEHHPVFLNNAVGKLKKMPEGPDGNKNCCS
CCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSTQFFKCLADDTRLKILILIQHENELCVGELMVALDDSQTKVSRHLAQLRQCGLLLVR
CCCHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHEECCCHHHHHHHHHHHHHCCHHEEE
KQRQWAYYRLNPNLAFWMKEIIKLTTEHHPVFLNNAVGKLKKMPEGPDGNKNCCS
CCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEECHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]