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The map label for this gene is gap3 [H]

Identifier: 119947238

GI number: 119947238

Start: 4450722

End: 4451726

Strand: Reverse

Name: gap3 [H]

Synonym: Ping_3636

Alternate gene names: 119947238

Gene position: 4451726-4450722 (Counterclockwise)

Preceding gene: 119947239

Following gene: 119947237

Centisome position: 97.63

GC content: 43.78

Gene sequence:

>1005_bases
ATGACAATTAAGATTGGCATTAATGGTTTTGGCCGCATTGGACGTTTAGCTTTACGTGCCTCTTGGGAATGGCCTGATTT
TGAATTTGTACAAATTAATGATCCTGCCGGTGATGCAAAAACCTTGGCACATTTACTTAATTTTGATTCTATTCATGGTC
GCTGGAGCTCACAAGCTGAAGCTTTAGACGATACTATTGTTTGTGATGGTAAAACCATCAAGGTCACTCACAACAAAGAG
ATAGGTGCAACAGACTGGTCGAACTGTGATGTGGTGATTGAAGCATCGGGTGTTATGCGCAAAAAATCCTTATTGCAGGC
TTATTTAGACCAGGGAGTGAAACGTGTTGTGGTGAGCGCGCCCGTTAAAGAGGAGGGAGTATTGAACGTTGTGATGGGAG
TCAATGATCACCTTTTTGATTATGATGCGCATCAAATCGTCACGGCAGCCTCTTGTACTACAAATTGTCTTGGTCCGGTT
ATTAAGGTGATTCAGGAACAATTTGGTATTAAACACGGTTCTATGACCACTATTCATGATCTGACTAATACCCAAACTAT
CTTGGATGCGCCGCATAAGGATTTGCGTCGGGCCCGTGCTTGCGGCATGAGTTTAATTCCTACAACCACCGGATCGGCAA
CCGCTATTACTGAAATATTTCCGGAACTAAAAGGACGCTTAAATGGCCATGCGGTGCGTGTCCCCTTAGCCAATGCATCG
CTGACGGACTGTGTTTTTGAGTTAAACAAAAGTGTTACCGTTGAACAGGTTAATGAGGCATTGGAAAATGCGGCTAACGG
TGAGTTAAAGGGGGTGCTGGGTTATGAAAGTCGTCCATTGGTTTCCATCGATTATAAAACTGATCCACGCTCGAGTGTGA
TTGATGCGTTATCAACTATGGTGGTTAACGAGACACAACTTAAATTGTACGTCTGGTATGACAATGAATGGGGTTATGTT
AACCGCACCGCCGAACTAGTGCGCTTAGTGGGAACGGTAAAATAA

Upstream 100 bases:

>100_bases
ATTACTGATAGCCGATAGCTGATAGCCGATAGCTGATAGCTGATAGCCGATAGCTGATAACTGACAGCTGATAACTAATA
ACAAATTAAGGATATTAAAT

Downstream 100 bases:

>100_bases
TAATGAATACGCGATTTAATAAACTATCCGCGGAGTTGCGCCAGTATATGGTGGTTACCGCTAATTACTGGGCATTTACC
CTAACCGATGGTGCTTTACG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTIKIGINGFGRIGRLALRASWEWPDFEFVQINDPAGDAKTLAHLLNFDSIHGRWSSQAEALDDTIVCDGKTIKVTHNKE
IGATDWSNCDVVIEASGVMRKKSLLQAYLDQGVKRVVVSAPVKEEGVLNVVMGVNDHLFDYDAHQIVTAASCTTNCLGPV
IKVIQEQFGIKHGSMTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITEIFPELKGRLNGHAVRVPLANAS
LTDCVFELNKSVTVEQVNEALENAANGELKGVLGYESRPLVSIDYKTDPRSSVIDALSTMVVNETQLKLYVWYDNEWGYV
NRTAELVRLVGTVK

Sequences:

>Translated_334_residues
MTIKIGINGFGRIGRLALRASWEWPDFEFVQINDPAGDAKTLAHLLNFDSIHGRWSSQAEALDDTIVCDGKTIKVTHNKE
IGATDWSNCDVVIEASGVMRKKSLLQAYLDQGVKRVVVSAPVKEEGVLNVVMGVNDHLFDYDAHQIVTAASCTTNCLGPV
IKVIQEQFGIKHGSMTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITEIFPELKGRLNGHAVRVPLANAS
LTDCVFELNKSVTVEQVNEALENAANGELKGVLGYESRPLVSIDYKTDPRSSVIDALSTMVVNETQLKLYVWYDNEWGYV
NRTAELVRLVGTVK
>Mature_333_residues
TIKIGINGFGRIGRLALRASWEWPDFEFVQINDPAGDAKTLAHLLNFDSIHGRWSSQAEALDDTIVCDGKTIKVTHNKEI
GATDWSNCDVVIEASGVMRKKSLLQAYLDQGVKRVVVSAPVKEEGVLNVVMGVNDHLFDYDAHQIVTAASCTTNCLGPVI
KVIQEQFGIKHGSMTTIHDLTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITEIFPELKGRLNGHAVRVPLANASL
TDCVFELNKSVTVEQVNEALENAANGELKGVLGYESRPLVSIDYKTDPRSSVIDALSTMVVNETQLKLYVWYDNEWGYVN
RTAELVRLVGTVK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=328, Percent_Identity=38.719512195122, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=39.2749244712991, Blast_Score=247, Evalue=1e-65,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=43.202416918429, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=38.4615384615385, Blast_Score=241, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=39.5833333333333, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=38.9880952380952, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=38.6904761904762, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=38.6904761904762, Blast_Score=249, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=41.0876132930514, Blast_Score=271, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=39.8791540785499, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=39.8791540785499, Blast_Score=258, Evalue=7e-70,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=39.0909090909091, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=39.0909090909091, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=39.3939393939394, Blast_Score=243, Evalue=9e-65,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=39.3939393939394, Blast_Score=243, Evalue=9e-65,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=38.9570552147239, Blast_Score=238, Evalue=4e-63,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36635; Mature: 36504

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIGINGFGRIGRLALRASWEWPDFEFVQINDPAGDAKTLAHLLNFDSIHGRWSSQAE
CEEEEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCHHHCCCCCCHHH
ALDDTIVCDGKTIKVTHNKEIGATDWSNCDVVIEASGVMRKKSLLQAYLDQGVKRVVVSA
HCCCEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEC
PVKEEGVLNVVMGVNDHLFDYDAHQIVTAASCTTNCLGPVIKVIQEQFGIKHGSMTTIHD
CCCCCCCEEEEECCCCCEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
LTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITEIFPELKGRLNGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCH
LTDCVFELNKSVTVEQVNEALENAANGELKGVLGYESRPLVSIDYKTDPRSSVIDALSTM
HHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHH
VVNETQLKLYVWYDNEWGYVNRTAELVRLVGTVK
HCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIKIGINGFGRIGRLALRASWEWPDFEFVQINDPAGDAKTLAHLLNFDSIHGRWSSQAE
EEEEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCHHHCCCCCCHHH
ALDDTIVCDGKTIKVTHNKEIGATDWSNCDVVIEASGVMRKKSLLQAYLDQGVKRVVVSA
HCCCEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEC
PVKEEGVLNVVMGVNDHLFDYDAHQIVTAASCTTNCLGPVIKVIQEQFGIKHGSMTTIHD
CCCCCCCEEEEECCCCCEECCCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
LTNTQTILDAPHKDLRRARACGMSLIPTTTGSATAITEIFPELKGRLNGHAVRVPLANAS
CCCCHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCH
LTDCVFELNKSVTVEQVNEALENAANGELKGVLGYESRPLVSIDYKTDPRSSVIDALSTM
HHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHH
VVNETQLKLYVWYDNEWGYVNRTAELVRLVGTVK
HCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]