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The map label for this gene is yrbG [H]

Identifier: 119947227

GI number: 119947227

Start: 4441115

End: 4442095

Strand: Direct

Name: yrbG [H]

Synonym: Ping_3625

Alternate gene names: 119947227

Gene position: 4441115-4442095 (Clockwise)

Preceding gene: 119947226

Following gene: 119947230

Centisome position: 97.4

GC content: 41.28

Gene sequence:

>981_bases
GTGATAACATTATTACTGCCCGCCCTTGCGATTATCATTGGCTTTGCTTTACTCATCTGGAGTGCTGATAAATTCGTTTT
AGGTGCCTCAAATACTGCGCGTAGTTTTTCAATATCACCGCTTATTGTCGGCGTAGTGATTGTCGGTTTAGGGACCTCTG
CACCGGAAATGTTAGTCTCCGCAATAGCAGCTGCTCAGGGTAATACAGGTCTTTCTATCGGTAATGCGATCGGTTCAAAC
ATTACCAATATTGGTTTAATGTTAGGCGTGACCGCTATTTTCTATCCGCTGCATATTCATTCAAAACTGCTTAAACGGGA
AATGCCGCTATTATTGGCACTGCTTATATTTAGTTTATTTTTACTTTGGGATCAGAGACTTGGATTTTTAGATGGTCTGA
TTCTATTAACTATGATGGCTGCCATGTTGGTGTTTACAGTATGGGAAGCGAAAAGTCATAACACCGATAGCCTGCCACAG
GAAATACTCGATGAGTTGCCGGAGGAGGTAAGTAAAAGGGATGCATTAAAATGGTTAATCATTGGTATTGTGCTATTAAT
AGCGTCTTCTCGTCTTCTTGTTTGGGGCGCTGTTGATGTTGCTACCTACTTTGGTGTCAGTGATTTAATTATTGGTCTAA
CTATTGTAGCGATTGGCACCAGTTTACCGGAGCTGGCCGCCACTATAGCAGCAGCACGTAAAAAAGAGTTTGATTTAGCT
GTCGGCAATATTATCGGCTCCAATATCTTTAATATCTTAGGCGTAATGGCGTTACCCGGATTGATTCATCCGGACAACTT
TGATAGCGAAGTATTAACCCGAGATTATCCGGTGATGATAGCGTTAACCGTTTTGTTGATGCTTTTTTCAACCTCATGGC
GAAAAGGTAAAACCGCTGTTTTAGGGCGTATTAACGGGGTCATATTATTAACCGCTTATATTGCTTACATGGTCTGGTTA
TTTATTGATATGAGCGCTTAA

Upstream 100 bases:

>100_bases
AAATCTTTGATGGAGCCTGCTGGGATTGCAAACAGTCATTTTAGCGTTAAGATTAATTAACTAATGACTTTTTTTAAATA
AAAAATGGAGTTTATCTGTC

Downstream 100 bases:

>100_bases
TAATATAAAAAAGGCGTCCTATCGTTAGCGATGCAGCACCTAAACCGTTAAATCATAATCTCTGATCGGATCCAGCTGCA
TCAGATCGCCATAAATAAAT

Product: Na+/Ca+ antiporter, CaCA family protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MITLLLPALAIIIGFALLIWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTGLSIGNAIGSN
ITNIGLMLGVTAIFYPLHIHSKLLKREMPLLLALLIFSLFLLWDQRLGFLDGLILLTMMAAMLVFTVWEAKSHNTDSLPQ
EILDELPEEVSKRDALKWLIIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLA
VGNIIGSNIFNILGVMALPGLIHPDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAVLGRINGVILLTAYIAYMVWL
FIDMSA

Sequences:

>Translated_326_residues
MITLLLPALAIIIGFALLIWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTGLSIGNAIGSN
ITNIGLMLGVTAIFYPLHIHSKLLKREMPLLLALLIFSLFLLWDQRLGFLDGLILLTMMAAMLVFTVWEAKSHNTDSLPQ
EILDELPEEVSKRDALKWLIIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLA
VGNIIGSNIFNILGVMALPGLIHPDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAVLGRINGVILLTAYIAYMVWL
FIDMSA
>Mature_326_residues
MITLLLPALAIIIGFALLIWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVSAIAAAQGNTGLSIGNAIGSN
ITNIGLMLGVTAIFYPLHIHSKLLKREMPLLLALLIFSLFLLWDQRLGFLDGLILLTMMAAMLVFTVWEAKSHNTDSLPQ
EILDELPEEVSKRDALKWLIIGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLA
VGNIIGSNIFNILGVMALPGLIHPDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAVLGRINGVILLTAYIAYMVWL
FIDMSA

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=305, Percent_Identity=41.6393442622951, Blast_Score=203, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193208990, Length=84, Percent_Identity=45.2380952380952, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35073; Mature: 35073

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLLLPALAIIIGFALLIWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVS
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
AIAAAQGNTGLSIGNAIGSNITNIGLMLGVTAIFYPLHIHSKLLKREMPLLLALLIFSLF
HHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWDQRLGFLDGLILLTMMAAMLVFTVWEAKSHNTDSLPQEILDELPEEVSKRDALKWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLA
HHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGNIIGSNIFNILGVMALPGLIHPDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
LGRINGVILLTAYIAYMVWLFIDMSA
HHHHCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITLLLPALAIIIGFALLIWSADKFVLGASNTARSFSISPLIVGVVIVGLGTSAPEMLVS
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
AIAAAQGNTGLSIGNAIGSNITNIGLMLGVTAIFYPLHIHSKLLKREMPLLLALLIFSLF
HHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLWDQRLGFLDGLILLTMMAAMLVFTVWEAKSHNTDSLPQEILDELPEEVSKRDALKWLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IGIVLLIASSRLLVWGAVDVATYFGVSDLIIGLTIVAIGTSLPELAATIAAARKKEFDLA
HHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VGNIIGSNIFNILGVMALPGLIHPDNFDSEVLTRDYPVMIALTVLLMLFSTSWRKGKTAV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHH
LGRINGVILLTAYIAYMVWLFIDMSA
HHHHCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]