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The map label for this gene is ubiA

Identifier: 119947071

GI number: 119947071

Start: 4289412

End: 4290275

Strand: Direct

Name: ubiA

Synonym: Ping_3469

Alternate gene names: 119947071

Gene position: 4289412-4290275 (Clockwise)

Preceding gene: 119947070

Following gene: 119947076

Centisome position: 94.07

GC content: 40.86

Gene sequence:

>864_bases
ATGAATTTTTTTTGCAAAGAAAAACGCCAGGCCTACGTAGAATTAATGCGTATTAACAAACCCATTGGCACCCTTTTATT
ACTCTGGCCAACCCTCTGGGCATTGTGGATAGCCGCTCAGGGATTTCCTGATCTGGGTGTGTTAATCGTATTTTCAGCTG
GTGTTTTTTTAATGCGCAGCGCAGGGTGTGTGATTAATGATTTTGCAGATCGTAACATTGATGGTTTTGTCGAGCGTACC
AAACACCGCCCATTACCCTCCGGTCGCGCCACCAGCACAGAAGCGATTATTCTTTTTTTCATACTTGCCATCGTTTCTTT
CTTATTGGTGCTGACCCAAAACAGTTTAACCATTCAGTTGTCCTTTGCGGGTTTACTACTGGCCTTTGCCTACCCTTTTA
TGAAGCGTTTTACGCAGTTACCGCAACTTGTATTAGGTCTCGCTTTTAGTTGGTCTATCCCCATGGCATTTGCGGCACAG
GCGAACGCATTACCTGCTGTGGTTTGGATTATCTTTGCGGTTAATATTATTTGGACTATCGCTTACGATACCCTTTATGC
CATGGTGGACAGGGAAGATGATCTTAAAATAGGCGTGAAATCCACTGCTATTTTATTTGCCAGCAATGACAAGATAATTA
TTGCTTTATTACAACTGACTAGCCTGATTTTATTAAGCCTATTAGGCTGGTTGGAAGATTTAAATTGGATCTACTTTATT
GCCCTGCTGGTAGTTGGCGGTTTATTTTTAAGGCAACAACTGCAGATAAAAAACCGCGAAAAAACTGCTTGTTTTAAAGC
TTTTCTAGACAATAATTATGTTGGATTCGTTATTTTTGCTGGCTTGTTTTTGGGTTATTTATAG

Upstream 100 bases:

>100_bases
TTGATTTCCCCCTGTGGGGAAGACGTTCTCTTTTTTATGTTAATAACAAACCGTTATTGGTCAGTGAAGTCTTTTTACCT
GCTTCAGGCATCTATTTACC

Downstream 100 bases:

>100_bases
TTTCTGGATTATCTATAATAGATCAACAGCAGAATCGCGCCTTTAGGCAGGCTAAATAATAAGCGCCGAGCCTGAAGGCT
CAGTTCCGTGATATTAGCAG

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNFFCKEKRQAYVELMRINKPIGTLLLLWPTLWALWIAAQGFPDLGVLIVFSAGVFLMRSAGCVINDFADRNIDGFVERT
KHRPLPSGRATSTEAIILFFILAIVSFLLVLTQNSLTIQLSFAGLLLAFAYPFMKRFTQLPQLVLGLAFSWSIPMAFAAQ
ANALPAVVWIIFAVNIIWTIAYDTLYAMVDREDDLKIGVKSTAILFASNDKIIIALLQLTSLILLSLLGWLEDLNWIYFI
ALLVVGGLFLRQQLQIKNREKTACFKAFLDNNYVGFVIFAGLFLGYL

Sequences:

>Translated_287_residues
MNFFCKEKRQAYVELMRINKPIGTLLLLWPTLWALWIAAQGFPDLGVLIVFSAGVFLMRSAGCVINDFADRNIDGFVERT
KHRPLPSGRATSTEAIILFFILAIVSFLLVLTQNSLTIQLSFAGLLLAFAYPFMKRFTQLPQLVLGLAFSWSIPMAFAAQ
ANALPAVVWIIFAVNIIWTIAYDTLYAMVDREDDLKIGVKSTAILFASNDKIIIALLQLTSLILLSLLGWLEDLNWIYFI
ALLVVGGLFLRQQLQIKNREKTACFKAFLDNNYVGFVIFAGLFLGYL
>Mature_287_residues
MNFFCKEKRQAYVELMRINKPIGTLLLLWPTLWALWIAAQGFPDLGVLIVFSAGVFLMRSAGCVINDFADRNIDGFVERT
KHRPLPSGRATSTEAIILFFILAIVSFLLVLTQNSLTIQLSFAGLLLAFAYPFMKRFTQLPQLVLGLAFSWSIPMAFAAQ
ANALPAVVWIIFAVNIIWTIAYDTLYAMVDREDDLKIGVKSTAILFASNDKIIIALLQLTSLILLSLLGWLEDLNWIYFI
ALLVVGGLFLRQQLQIKNREKTACFKAFLDNNYVGFVIFAGLFLGYL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=281, Percent_Identity=35.9430604982206, Blast_Score=180, Evalue=1e-45,
Organism=Escherichia coli, GI1790473, Length=281, Percent_Identity=59.7864768683274, Blast_Score=337, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17553718, Length=277, Percent_Identity=37.5451263537906, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=35.5871886120996, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=186, Percent_Identity=40.8602150537634, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=46.0431654676259, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=45.6521739130435, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=235, Percent_Identity=34.0425531914894, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=42.0494699646643, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_PSYIN (A1T087)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944751.1
- STRING:   A1T087
- GeneID:   4625542
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3469
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- PhylomeDB:   A1T087
- BioCyc:   PING357804:PING_3469-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 32277; Mature: 32277

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1a7afd50)-; HASH(0x1ad08744)-; HASH(0x1aa64614)-; HASH(0x1b1a3958)-; HASH(0x1b3e35ec)-; HASH(0x1b1d97fc)-; HASH(0x1ae58aec)-; HASH(0x1b2d72e0)-; HASH(0x1ad769cc)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFCKEKRQAYVELMRINKPIGTLLLLWPTLWALWIAAQGFPDLGVLIVFSAGVFLMRS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
AGCVINDFADRNIDGFVERTKHRPLPSGRATSTEAIILFFILAIVSFLLVLTQNSLTIQL
CCCEEEHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SFAGLLLAFAYPFMKRFTQLPQLVLGLAFSWSIPMAFAAQANALPAVVWIIFAVNIIWTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
AYDTLYAMVDREDDLKIGVKSTAILFASNDKIIIALLQLTSLILLSLLGWLEDLNWIYFI
HHHHHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLVVGGLFLRQQLQIKNREKTACFKAFLDNNYVGFVIFAGLFLGYL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCH
>Mature Secondary Structure
MNFFCKEKRQAYVELMRINKPIGTLLLLWPTLWALWIAAQGFPDLGVLIVFSAGVFLMRS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
AGCVINDFADRNIDGFVERTKHRPLPSGRATSTEAIILFFILAIVSFLLVLTQNSLTIQL
CCCEEEHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SFAGLLLAFAYPFMKRFTQLPQLVLGLAFSWSIPMAFAAQANALPAVVWIIFAVNIIWTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHH
AYDTLYAMVDREDDLKIGVKSTAILFASNDKIIIALLQLTSLILLSLLGWLEDLNWIYFI
HHHHHHHHHCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLVVGGLFLRQQLQIKNREKTACFKAFLDNNYVGFVIFAGLFLGYL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA