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The map label for this gene is ubiC

Identifier: 119947070

GI number: 119947070

Start: 4288855

End: 4289415

Strand: Direct

Name: ubiC

Synonym: Ping_3468

Alternate gene names: 119947070

Gene position: 4288855-4289415 (Clockwise)

Preceding gene: 119947069

Following gene: 119947071

Centisome position: 94.06

GC content: 39.75

Gene sequence:

>561_bases
ATGGATATTACTATCACTCCTCTGGCATCTTCAACTCTTTGGTCAGCCGATATAACACCCACAACCTGCTCAGAAAATCT
GCTTGATTGGCTTTTAGATCAGAACTCTTTAACGCGTAAGCTACAAGCTTTATCAGCAGACTTTAAGGTAAAGGTCAGGC
AGCAAGTGACTTTAAGCCACAGTAAAGATTTACTTTCTCCCTATTTTTCTGAAGAAAATAAGGTCTTAGTGCGTGAAGTA
CTTTTAGTTTGTGATAATAAACCGGTGGTATTTGCTCAAACTGAAATCCCGTTTAGTACCTTAACTGATCAGCAGGCAAA
ACTGGCGGAAATTGGCACAGATTCATTAGGCACATTTTTATTTCAAGATCCGAGCATGAGACGCGATAAAATTGAAGTTG
CACAGTTCCCGGTGTATTCTGCTGTGCATCAACTGTGCATTGATCTTAATCAAGAGGTTGATTTCCCCCTGTGGGGAAGA
CGTTCTCTTTTTTATGTTAATAACAAACCGTTATTGGTCAGTGAAGTCTTTTTACCTGCTTCAGGCATCTATTTACCATG
A

Upstream 100 bases:

>100_bases
ATATATGTTGGCATTCAGAAACAACAGTGACCTTTGCCACCACTTATGGTTATAATCCTATATCACTAACTATCTTGTTA
TAGAAAGGCTTTAATCGTTA

Downstream 100 bases:

>100_bases
ATTTTTTTTGCAAAGAAAAACGCCAGGCCTACGTAGAATTAATGCGTATTAACAAACCCATTGGCACCCTTTTATTACTC
TGGCCAACCCTCTGGGCATT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDITITPLASSTLWSADITPTTCSENLLDWLLDQNSLTRKLQALSADFKVKVRQQVTLSHSKDLLSPYFSEENKVLVREV
LLVCDNKPVVFAQTEIPFSTLTDQQAKLAEIGTDSLGTFLFQDPSMRRDKIEVAQFPVYSAVHQLCIDLNQEVDFPLWGR
RSLFYVNNKPLLVSEVFLPASGIYLP

Sequences:

>Translated_186_residues
MDITITPLASSTLWSADITPTTCSENLLDWLLDQNSLTRKLQALSADFKVKVRQQVTLSHSKDLLSPYFSEENKVLVREV
LLVCDNKPVVFAQTEIPFSTLTDQQAKLAEIGTDSLGTFLFQDPSMRRDKIEVAQFPVYSAVHQLCIDLNQEVDFPLWGR
RSLFYVNNKPLLVSEVFLPASGIYLP
>Mature_186_residues
MDITITPLASSTLWSADITPTTCSENLLDWLLDQNSLTRKLQALSADFKVKVRQQVTLSHSKDLLSPYFSEENKVLVREV
LLVCDNKPVVFAQTEIPFSTLTDQQAKLAEIGTDSLGTFLFQDPSMRRDKIEVAQFPVYSAVHQLCIDLNQEVDFPLWGR
RSLFYVNNKPLLVSEVFLPASGIYLP

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=160, Percent_Identity=31.875, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_PSYIN (A1T086)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944750.1
- ProteinModelPortal:   A1T086
- SMR:   A1T086
- STRING:   A1T086
- GeneID:   4625541
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3468
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   PLGELLY
- BioCyc:   PING357804:PING_3468-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 21009; Mature: 21009

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: BINDING 78-78 BINDING 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITITPLASSTLWSADITPTTCSENLLDWLLDQNSLTRKLQALSADFKVKVRQQVTLSH
CCEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEHHH
SKDLLSPYFSEENKVLVREVLLVCDNKPVVFAQTEIPFSTLTDQQAKLAEIGTDSLGTFL
CHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCHHHHHHCCCCCHHHEE
FQDPSMRRDKIEVAQFPVYSAVHQLCIDLNQEVDFPLWGRRSLFYVNNKPLLVSEVFLPA
ECCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEEECCC
SGIYLP
CCCCCC
>Mature Secondary Structure
MDITITPLASSTLWSADITPTTCSENLLDWLLDQNSLTRKLQALSADFKVKVRQQVTLSH
CCEEECCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEHHH
SKDLLSPYFSEENKVLVREVLLVCDNKPVVFAQTEIPFSTLTDQQAKLAEIGTDSLGTFL
CHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCHHHHHHCCCCCHHHEE
FQDPSMRRDKIEVAQFPVYSAVHQLCIDLNQEVDFPLWGRRSLFYVNNKPLLVSEVFLPA
ECCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEEECCC
SGIYLP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA