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The map label for this gene is cysJ [H]

Identifier: 119947037

GI number: 119947037

Start: 4244919

End: 4246721

Strand: Direct

Name: cysJ [H]

Synonym: Ping_3434

Alternate gene names: 119947037

Gene position: 4244919-4246721 (Clockwise)

Preceding gene: 119947036

Following gene: 119947038

Centisome position: 93.1

GC content: 42.26

Gene sequence:

>1803_bases
ATGGCTTTTAACAATATCTCGGCCTTAACTTCTCCTTTATCTGAGTTGCAGTTATCACATCTGCAACAGGCGACGACTGA
TTTAACCCCAGTGCAGACAGCCTGGATAAGCGGCTATCTCGCCGGTATAAGCCAGACCCCGGCAACCGTCGAAACCGTCG
AAACGGCTGTTAGCTCGGGCCAACACCTGACCATATTATTTGGCTCACAAACGGGCAATTGTAAAGGTGTTGCAGAGCAA
TTGGCGGATCAGGCAGCTGCTAAAGGTATCACGCATACTTTAATTTCTATGGCTGATTATAAGGTTAAAAATATTAAAGA
TGAAAGTCATCTTATTGTTGTGGTAAGTACCAACGGTGAAGGTGAAGCACCGGATGATGCTATTGATTTGCATGAATTTT
TAGCGACTAAAAAAGCGCCAAAATTAGACAACTTAAAGTTTGCGGTATTGGCGCTTGGTGATTCAAGTTACGAATTTTTC
TGTCAAACAGGGAAAGATTTTGATCAACGTTTAGCTGCGCTTGGGGCAACGGCTATTGTCGATCGCTTAGATGCCGATAT
CGATTACGAGCAACAGACCCCGGGGTGGTTCGAAAAAGTATTAAATAAAGTTGAACAAACACTTGAAAAAGGCGGTTTTG
TAGCCCCCTCTAAAGCCACACTCGAAACCCCTTTAAGTGTCAATAAATATGACAAGAAGAGCCCTTTTGCAGCGAGTTTG
CTAACCAGTCAAAAAATTACCGGTGCCCGCTCTGCAAAAGATGTCCGCCATATTGAAATTGATTTAGAAGGCTCAGATCT
GCATTATAAAGTGGGTGATGCATTGGGGGTTTGGTTTGAAAACGATCCACAGTTGGTTGATGCATTAATCAAAAAACTTA
AACTGGATCCGCAAGAGCAAGTTAAGATAGATGATAAAAATATTTCCTTAAAACAGGCGTTAACTGAATCCTTCGAGTTA
ACCGCTACCCATCCGGCTTTTGTAGAAGGTTATGCCAAGTTAACCAAGAACAAAAAATTATTGACCCTAGCTGAAGATAA
AAATAAATTACGTGATTTTGCTAATACGCATCAAATTATTGATGTGCTCAGCAAAAAAGGCAGTAAAGCTGTTACTGCTG
AAAAATTTGTGACTTTACTGCGCCACCTCAGTCCGCGTTTATATTCAATCGCCTCAAGCCAAGCTGAAGTCGAGCAGGAG
GTACATCTTACGGTTGCTGCACTGACATTTGAGAATGAAGAGGGTGAAGTGCGCCAAGGTGGTGCTTCAGGATTCCTCGC
GCATCGTTTGCAGGAAGGTCAACAAGTAAAGGTGTTTATCGAAGATAATCATAACTTCCGTTTACCCAGCAACCCGGAAA
CACCTGTTATTATGGTTGGACCTGGCACCGGTATTGCACCTTTCCGCGCATTTTTGCAGGAACGTGATGCAACGGAGGCA
ACGGGTAAAAACTGGTTGTTTTTCGGCGAGCAAACTTTCACTGAAGATTTTTTATATCAAACAGAATGGCAAGGTTTCTT
AAAATCAGGTTTATTAACAAATCTGGATTTAGCTTTCTCTCGCGACCAAGCTGAGAAAATTTACGTTCAGGATCGCCTTA
AAGAACATGCCCATGAAATTTATCAATGGTTACAGGAAGGTGCACATTTTTATGTCTGCGGTGATGCCAACCGGATGGCC
AAAGATGTCCAACAAACATTAATCGAAATTATCGGCTCTCAAGGCAAGAAAAGCCTCGAAGATGCAGAGCAATATTTAAC
TGAATTACGTCAAGCAAAACGCTACCAAAGGGATGTCTACTAA

Upstream 100 bases:

>100_bases
AATTCTATTTTGTTATAAAAAATCAGATTTTAATCTTTCGCCATTGCCAAATAAGACCGTAGTATATCTGCATACTTAAT
GGAATTATGGAAATAGCAAC

Downstream 100 bases:

>100_bases
TGAGCAAGAAATTACACGATAACGAACGTATTAAAATTGAAAGTAACTTTCTTCGCGGTAAATTAGTGGAAGGACTGAAT
GATAATACTACCGGTGCCTT

Product: sulfite reductase (NADPH) flavoprotein, alpha chain

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MAFNNISALTSPLSELQLSHLQQATTDLTPVQTAWISGYLAGISQTPATVETVETAVSSGQHLTILFGSQTGNCKGVAEQ
LADQAAAKGITHTLISMADYKVKNIKDESHLIVVVSTNGEGEAPDDAIDLHEFLATKKAPKLDNLKFAVLALGDSSYEFF
CQTGKDFDQRLAALGATAIVDRLDADIDYEQQTPGWFEKVLNKVEQTLEKGGFVAPSKATLETPLSVNKYDKKSPFAASL
LTSQKITGARSAKDVRHIEIDLEGSDLHYKVGDALGVWFENDPQLVDALIKKLKLDPQEQVKIDDKNISLKQALTESFEL
TATHPAFVEGYAKLTKNKKLLTLAEDKNKLRDFANTHQIIDVLSKKGSKAVTAEKFVTLLRHLSPRLYSIASSQAEVEQE
VHLTVAALTFENEEGEVRQGGASGFLAHRLQEGQQVKVFIEDNHNFRLPSNPETPVIMVGPGTGIAPFRAFLQERDATEA
TGKNWLFFGEQTFTEDFLYQTEWQGFLKSGLLTNLDLAFSRDQAEKIYVQDRLKEHAHEIYQWLQEGAHFYVCGDANRMA
KDVQQTLIEIIGSQGKKSLEDAEQYLTELRQAKRYQRDVY

Sequences:

>Translated_600_residues
MAFNNISALTSPLSELQLSHLQQATTDLTPVQTAWISGYLAGISQTPATVETVETAVSSGQHLTILFGSQTGNCKGVAEQ
LADQAAAKGITHTLISMADYKVKNIKDESHLIVVVSTNGEGEAPDDAIDLHEFLATKKAPKLDNLKFAVLALGDSSYEFF
CQTGKDFDQRLAALGATAIVDRLDADIDYEQQTPGWFEKVLNKVEQTLEKGGFVAPSKATLETPLSVNKYDKKSPFAASL
LTSQKITGARSAKDVRHIEIDLEGSDLHYKVGDALGVWFENDPQLVDALIKKLKLDPQEQVKIDDKNISLKQALTESFEL
TATHPAFVEGYAKLTKNKKLLTLAEDKNKLRDFANTHQIIDVLSKKGSKAVTAEKFVTLLRHLSPRLYSIASSQAEVEQE
VHLTVAALTFENEEGEVRQGGASGFLAHRLQEGQQVKVFIEDNHNFRLPSNPETPVIMVGPGTGIAPFRAFLQERDATEA
TGKNWLFFGEQTFTEDFLYQTEWQGFLKSGLLTNLDLAFSRDQAEKIYVQDRLKEHAHEIYQWLQEGAHFYVCGDANRMA
KDVQQTLIEIIGSQGKKSLEDAEQYLTELRQAKRYQRDVY
>Mature_599_residues
AFNNISALTSPLSELQLSHLQQATTDLTPVQTAWISGYLAGISQTPATVETVETAVSSGQHLTILFGSQTGNCKGVAEQL
ADQAAAKGITHTLISMADYKVKNIKDESHLIVVVSTNGEGEAPDDAIDLHEFLATKKAPKLDNLKFAVLALGDSSYEFFC
QTGKDFDQRLAALGATAIVDRLDADIDYEQQTPGWFEKVLNKVEQTLEKGGFVAPSKATLETPLSVNKYDKKSPFAASLL
TSQKITGARSAKDVRHIEIDLEGSDLHYKVGDALGVWFENDPQLVDALIKKLKLDPQEQVKIDDKNISLKQALTESFELT
ATHPAFVEGYAKLTKNKKLLTLAEDKNKLRDFANTHQIIDVLSKKGSKAVTAEKFVTLLRHLSPRLYSIASSQAEVEQEV
HLTVAALTFENEEGEVRQGGASGFLAHRLQEGQQVKVFIEDNHNFRLPSNPETPVIMVGPGTGIAPFRAFLQERDATEAT
GKNWLFFGEQTFTEDFLYQTEWQGFLKSGLLTNLDLAFSRDQAEKIYVQDRLKEHAHEIYQWLQEGAHFYVCGDANRMAK
DVQQTLIEIIGSQGKKSLEDAEQYLTELRQAKRYQRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI7657393, Length=596, Percent_Identity=31.2080536912752, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI221316709, Length=596, Percent_Identity=31.2080536912752, Blast_Score=249, Evalue=6e-66,
Organism=Homo sapiens, GI221316705, Length=605, Percent_Identity=30.7438016528926, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI127139033, Length=613, Percent_Identity=29.2006525285481, Blast_Score=242, Evalue=7e-64,
Organism=Homo sapiens, GI221316707, Length=526, Percent_Identity=31.7490494296578, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI24041029, Length=606, Percent_Identity=29.7029702970297, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI10835173, Length=643, Percent_Identity=28.6158631415241, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI40254422, Length=643, Percent_Identity=27.2161741835148, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI169790956, Length=445, Percent_Identity=30.561797752809, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI169790958, Length=445, Percent_Identity=30.561797752809, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI1789123, Length=593, Percent_Identity=52.7824620573356, Blast_Score=623, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17554134, Length=627, Percent_Identity=30.4625199362041, Blast_Score=248, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17566446, Length=588, Percent_Identity=27.5510204081633, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17531441, Length=416, Percent_Identity=25.9615384615385, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32563863, Length=125, Percent_Identity=34.4, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321832, Length=662, Percent_Identity=27.3413897280967, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321143, Length=394, Percent_Identity=28.6802030456853, Blast_Score=163, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6325305, Length=263, Percent_Identity=28.8973384030418, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322597, Length=140, Percent_Identity=32.8571428571429, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17137192, Length=611, Percent_Identity=32.2422258592471, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24582192, Length=514, Percent_Identity=32.295719844358, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI78706872, Length=529, Percent_Identity=31.0018903591682, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24583543, Length=529, Percent_Identity=31.0018903591682, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI78706876, Length=529, Percent_Identity=31.0018903591682, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24660907, Length=593, Percent_Identity=25.8010118043845, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24660903, Length=593, Percent_Identity=25.8010118043845, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24647438, Length=406, Percent_Identity=23.6453201970443, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 66615; Mature: 66483

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNNISALTSPLSELQLSHLQQATTDLTPVQTAWISGYLAGISQTPATVETVETAVSSG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
QHLTILFGSQTGNCKGVAEQLADQAAAKGITHTLISMADYKVKNIKDESHLIVVVSTNGE
CEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GEAPDDAIDLHEFLATKKAPKLDNLKFAVLALGDSSYEFFCQTGKDFDQRLAALGATAIV
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
DRLDADIDYEQQTPGWFEKVLNKVEQTLEKGGFVAPSKATLETPLSVNKYDKKSPFAASL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LTSQKITGARSAKDVRHIEIDLEGSDLHYKVGDALGVWFENDPQLVDALIKKLKLDPQEQ
HHHHHCCCCCCCCCCEEEEEEECCCCEEEEECCEEEEEECCCHHHHHHHHHHHCCCCHHH
VKIDDKNISLKQALTESFELTATHPAFVEGYAKLTKNKKLLTLAEDKNKLRDFANTHQII
EEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHH
DVLSKKGSKAVTAEKFVTLLRHLSPRLYSIASSQAEVEQEVHLTVAALTFENEEGEVRQG
HHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCHHCC
GASGFLAHRLQEGQQVKVFIEDNHNFRLPSNPETPVIMVGPGTGIAPFRAFLQERDATEA
CCHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
TGKNWLFFGEQTFTEDFLYQTEWQGFLKSGLLTNLDLAFSRDQAEKIYVQDRLKEHAHEI
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHH
YQWLQEGAHFYVCGDANRMAKDVQQTLIEIIGSQGKKSLEDAEQYLTELRQAKRYQRDVY
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFNNISALTSPLSELQLSHLQQATTDLTPVQTAWISGYLAGISQTPATVETVETAVSSG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
QHLTILFGSQTGNCKGVAEQLADQAAAKGITHTLISMADYKVKNIKDESHLIVVVSTNGE
CEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GEAPDDAIDLHEFLATKKAPKLDNLKFAVLALGDSSYEFFCQTGKDFDQRLAALGATAIV
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHH
DRLDADIDYEQQTPGWFEKVLNKVEQTLEKGGFVAPSKATLETPLSVNKYDKKSPFAASL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
LTSQKITGARSAKDVRHIEIDLEGSDLHYKVGDALGVWFENDPQLVDALIKKLKLDPQEQ
HHHHHCCCCCCCCCCEEEEEEECCCCEEEEECCEEEEEECCCHHHHHHHHHHHCCCCHHH
VKIDDKNISLKQALTESFELTATHPAFVEGYAKLTKNKKLLTLAEDKNKLRDFANTHQII
EEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHH
DVLSKKGSKAVTAEKFVTLLRHLSPRLYSIASSQAEVEQEVHLTVAALTFENEEGEVRQG
HHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCHHCC
GASGFLAHRLQEGQQVKVFIEDNHNFRLPSNPETPVIMVGPGTGIAPFRAFLQERDATEA
CCHHHHHHHHCCCCEEEEEEECCCCEECCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
TGKNWLFFGEQTFTEDFLYQTEWQGFLKSGLLTNLDLAFSRDQAEKIYVQDRLKEHAHEI
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHHHH
YQWLQEGAHFYVCGDANRMAKDVQQTLIEIIGSQGKKSLEDAEQYLTELRQAKRYQRDVY
HHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA