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The map label for this gene is rhtC [H]

Identifier: 119947007

GI number: 119947007

Start: 4204945

End: 4205580

Strand: Direct

Name: rhtC [H]

Synonym: Ping_3404

Alternate gene names: 119947007

Gene position: 4204945-4205580 (Clockwise)

Preceding gene: 119947005

Following gene: 119947010

Centisome position: 92.22

GC content: 42.61

Gene sequence:

>636_bases
ATGATCGCACCTTATATTGATGAGTTTTTAATGCTTACTCTGGTCCATTTTCTAGCCGTTATTGCACCGGGCCCAGATTT
TGCCGTGGTGATCCGCCAAAGTATCAGCTTTGGCCGTAAAAGCGCACTGATCACAAGCTTAGGCATTGGTACGGGTATTT
CAATACACGTACTTTATACCCTGCTGGGAATAGGTTTTATTATTACACAATCGGAAACGGCCTTTATGGTCGCTAAAATT
GCCGGTGCGTTATATCTAACCTATATCGGCTTTAATATGCTCGCTAGCAAAGCCCAAAATCAGACAGATCCTCAAGTGGT
TATTGACTCGGACTTAAATCATCACAAAGGCGCTTTTATGCTCGGCTTTATGACCAATTTATTAAACCCTAAAGCGACCC
TGTTTTTTTTGGCAATCTTTACTGCTATCGTCAGTATTGATACACCGCTCGCCGTGCAAAGTATTTATGGGCTTTGGATA
GCGCTTACCACCGCATTGTGGTTTTCGCTGGTATCATTATTTTTCTCCCACCGACATGTGCGGGCTAAATTTGTTCGCCA
CGGTTATCTTTTTGAACGGGTAATGGGGGGCATATTATTGCTATTTGCGGCAAAATTAGGATGGTCTTTATTTTAG

Upstream 100 bases:

>100_bases
GTTATATAAAATATTAACGGATTGACTGACAAGTTCTATACAGATTTATTCAGATCAGTATTTAAATAATACTAACCTGA
ATGCCCTTTTTGGAGAAACA

Downstream 100 bases:

>100_bases
TGTGGCCTGCAACTCAGCCAAAGCATTAATGATTTCAAAAAGAGATTAATAACATTTGTGCAGGAAAATTAAAGGAACAC
ATTATGACCCTTTCCTGAGT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIAPYIDEFLMLTLVHFLAVIAPGPDFAVVIRQSISFGRKSALITSLGIGTGISIHVLYTLLGIGFIITQSETAFMVAKI
AGALYLTYIGFNMLASKAQNQTDPQVVIDSDLNHHKGAFMLGFMTNLLNPKATLFFLAIFTAIVSIDTPLAVQSIYGLWI
ALTTALWFSLVSLFFSHRHVRAKFVRHGYLFERVMGGILLLFAAKLGWSLF

Sequences:

>Translated_211_residues
MIAPYIDEFLMLTLVHFLAVIAPGPDFAVVIRQSISFGRKSALITSLGIGTGISIHVLYTLLGIGFIITQSETAFMVAKI
AGALYLTYIGFNMLASKAQNQTDPQVVIDSDLNHHKGAFMLGFMTNLLNPKATLFFLAIFTAIVSIDTPLAVQSIYGLWI
ALTTALWFSLVSLFFSHRHVRAKFVRHGYLFERVMGGILLLFAAKLGWSLF
>Mature_211_residues
MIAPYIDEFLMLTLVHFLAVIAPGPDFAVVIRQSISFGRKSALITSLGIGTGISIHVLYTLLGIGFIITQSETAFMVAKI
AGALYLTYIGFNMLASKAQNQTDPQVVIDSDLNHHKGAFMLGFMTNLLNPKATLFFLAIFTAIVSIDTPLAVQSIYGLWI
ALTTALWFSLVSLFFSHRHVRAKFVRHGYLFERVMGGILLLFAAKLGWSLF

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=179, Percent_Identity=30.7262569832402, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786522, Length=189, Percent_Identity=30.1587301587302, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788099, Length=191, Percent_Identity=24.6073298429319, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23264; Mature: 23264

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPYIDEFLMLTLVHFLAVIAPGPDFAVVIRQSISFGRKSALITSLGIGTGISIHVLYT
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LLGIGFIITQSETAFMVAKIAGALYLTYIGFNMLASKAQNQTDPQVVIDSDLNHHKGAFM
HHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHH
LGFMTNLLNPKATLFFLAIFTAIVSIDTPLAVQSIYGLWIALTTALWFSLVSLFFSHRHV
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKFVRHGYLFERVMGGILLLFAAKLGWSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIAPYIDEFLMLTLVHFLAVIAPGPDFAVVIRQSISFGRKSALITSLGIGTGISIHVLYT
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHH
LLGIGFIITQSETAFMVAKIAGALYLTYIGFNMLASKAQNQTDPQVVIDSDLNHHKGAFM
HHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHH
LGFMTNLLNPKATLFFLAIFTAIVSIDTPLAVQSIYGLWIALTTALWFSLVSLFFSHRHV
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKFVRHGYLFERVMGGILLLFAAKLGWSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]