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The map label for this gene is map [H]

Identifier: 119946624

GI number: 119946624

Start: 3701051

End: 3701839

Strand: Direct

Name: map [H]

Synonym: Ping_3003

Alternate gene names: 119946624

Gene position: 3701051-3701839 (Clockwise)

Preceding gene: 119946622

Following gene: 119946625

Centisome position: 81.17

GC content: 38.91

Gene sequence:

>789_bases
ATGACTGGAATCATTAAAACATCCGAAGAAATCGAAAAAATGCGTATTGCCGGACAACTGGCTGCAGATGTATTGACGAT
GATCGAACCTTTTATTCAAATAGGGGTCACGACTAATGAATTGGACAAAATCTGCCATGATTATATTGTTGACGTACAAG
GCTGTATCCCGGCACCTTTAAATTACCACGGTTTTCCAAAATCAGTCTGTACATCGGTTAACTATGTAGTCTGTCATGGT
ATTCCCAATGATAAAGCATTAAGGGACGGGGATTCAATAAACATTGATATCACGGTTATTAAAGATGGTTATCACGGTGA
TACGTCAAAAATGTTTTTCGTTGGTAAACCTTCTATTCAAGCGGAACGTCTAGCACGTATTACGCAGGAATGTTTATATC
TGGGAATTAATTTAGTAAAACCCGGCGCACGCTTGGGCGATATCGGTGCAGCAATTCAAAAACATGCAGAAAAAAACAGT
TATTCTGTAGTGCGTGAATACTGTGGTCATGGTATTGGCACTGGCTTTCATGAAGAGCCACAAGTATTACATTATGGTAA
AGCCAATACAGGCGAAGTGATTAAAGTAGGCCAGTGCTTTACTATTGAGCCGATGATCAATGCGGGTAAAAAAACCTGTA
AAGTCCTTGGTGATGATTGGACTGTTATTACAAAAGATAAAAAATTATCGGCACAATGGGAACATACTTTATTAGTCACT
GAAACTGGTGTAGAGATATTAACCCTGCGCCCTGAAGAAACCATTGCACGTGTTATTAATCATAACTAA

Upstream 100 bases:

>100_bases
TTCCCATATCAATAAAAGGATTTAACTTCGCTGGCTTCATTGCGATAAATTCTTTATAGTAATATTTAAATTTATAAGTA
ACAATTAAAGAGAATAAAAT

Downstream 100 bases:

>100_bases
TTTAAATCCTAAAAATTAAACCTTTCTTCATTCTAATACCAATTCCACTCATTAGATGGTCTATTTAGGTGTAGGAAAAA
TGGATGAAAGCAAGGCATTG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTGIIKTSEEIEKMRIAGQLAADVLTMIEPFIQIGVTTNELDKICHDYIVDVQGCIPAPLNYHGFPKSVCTSVNYVVCHG
IPNDKALRDGDSINIDITVIKDGYHGDTSKMFFVGKPSIQAERLARITQECLYLGINLVKPGARLGDIGAAIQKHAEKNS
YSVVREYCGHGIGTGFHEEPQVLHYGKANTGEVIKVGQCFTIEPMINAGKKTCKVLGDDWTVITKDKKLSAQWEHTLLVT
ETGVEILTLRPEETIARVINHN

Sequences:

>Translated_262_residues
MTGIIKTSEEIEKMRIAGQLAADVLTMIEPFIQIGVTTNELDKICHDYIVDVQGCIPAPLNYHGFPKSVCTSVNYVVCHG
IPNDKALRDGDSINIDITVIKDGYHGDTSKMFFVGKPSIQAERLARITQECLYLGINLVKPGARLGDIGAAIQKHAEKNS
YSVVREYCGHGIGTGFHEEPQVLHYGKANTGEVIKVGQCFTIEPMINAGKKTCKVLGDDWTVITKDKKLSAQWEHTLLVT
ETGVEILTLRPEETIARVINHN
>Mature_261_residues
TGIIKTSEEIEKMRIAGQLAADVLTMIEPFIQIGVTTNELDKICHDYIVDVQGCIPAPLNYHGFPKSVCTSVNYVVCHGI
PNDKALRDGDSINIDITVIKDGYHGDTSKMFFVGKPSIQAERLARITQECLYLGINLVKPGARLGDIGAAIQKHAEKNSY
SVVREYCGHGIGTGFHEEPQVLHYGKANTGEVIKVGQCFTIEPMINAGKKTCKVLGDDWTVITKDKKLSAQWEHTLLVTE
TGVEILTLRPEETIARVINHN

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=244, Percent_Identity=51.2295081967213, Blast_Score=251, Evalue=6e-67,
Organism=Homo sapiens, GI40385867, Length=251, Percent_Identity=42.2310756972112, Blast_Score=204, Evalue=6e-53,
Organism=Escherichia coli, GI1786364, Length=259, Percent_Identity=65.2509652509653, Blast_Score=355, Evalue=1e-99,
Organism=Escherichia coli, GI1788728, Length=258, Percent_Identity=24.031007751938, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=48.1781376518219, Blast_Score=236, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=47.7732793522267, Blast_Score=238, Evalue=7e-64,
Organism=Drosophila melanogaster, GI21355531, Length=244, Percent_Identity=49.5901639344262, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=43.4426229508197, Blast_Score=214, Evalue=3e-56,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28847; Mature: 28715

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIIKTSEEIEKMRIAGQLAADVLTMIEPFIQIGVTTNELDKICHDYIVDVQGCIPAPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
NYHGFPKSVCTSVNYVVCHGIPNDKALRDGDSINIDITVIKDGYHGDTSKMFFVGKPSIQ
CCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCH
AERLARITQECLYLGINLVKPGARLGDIGAAIQKHAEKNSYSVVREYCGHGIGTGFHEEP
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
QVLHYGKANTGEVIKVGQCFTIEPMINAGKKTCKVLGDDWTVITKDKKLSAQWEHTLLVT
CEEEECCCCCCCEEEECCEEEECHHHHCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEE
ETGVEILTLRPEETIARVINHN
ECCEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure 
TGIIKTSEEIEKMRIAGQLAADVLTMIEPFIQIGVTTNELDKICHDYIVDVQGCIPAPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
NYHGFPKSVCTSVNYVVCHGIPNDKALRDGDSINIDITVIKDGYHGDTSKMFFVGKPSIQ
CCCCCCHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEECCCCH
AERLARITQECLYLGINLVKPGARLGDIGAAIQKHAEKNSYSVVREYCGHGIGTGFHEEP
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
QVLHYGKANTGEVIKVGQCFTIEPMINAGKKTCKVLGDDWTVITKDKKLSAQWEHTLLVT
CEEEECCCCCCCEEEECCEEEECHHHHCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEE
ETGVEILTLRPEETIARVINHN
ECCEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]