| Definition | Psychromonas ingrahamii 37, complete genome. |
|---|---|
| Accession | NC_008709 |
| Length | 4,559,598 |
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The map label for this gene is dxr
Identifier: 119946591
GI number: 119946591
Start: 3663361
End: 3664560
Strand: Reverse
Name: dxr
Synonym: Ping_2970
Alternate gene names: 119946591
Gene position: 3664560-3663361 (Counterclockwise)
Preceding gene: 119946592
Following gene: 119946590
Centisome position: 80.37
GC content: 42.58
Gene sequence:
>1200_bases ATGAAAAAATTAGCTATATTAGGCGCAACGGGTTCGATAGGAGATAGTACACTCAGTGTTTGCCGGAGTAACCCTGAGTT ATATCAGATTACCTTATTAGCAGCCTCATCCAGTGTTGATAAAATGCTAGCGCTGTGCCGCGAGTTTACCCCATTGTATG TTTCAATGAGCAGTGAAATATCGGCTAAAAAATTGCGCGGTTTACTCAAAAGAAACAATTTATCATGCCATGTGCTTGAT GATGAGCAGCGGTTATTAGAATTACTCGCAAGTGATCATGTGGATTCAGTGATGGCTGCTATCGTTGGAGCTGCAGGGTT AAAAACAACACTTGCGGCGGTTGATGCGGGTAAAGAAGTTTTTTTAGCCAACAAAGAAGCGTTGGTTATGTCCGGCGCAC TGTTTATTGATGCGGTTAAAAAGTCTGGCGCAAAGCTTTGGCCCGTTGATAGTGAGCATAATGCTATTTACCAAGCGTTA TCACCCAAGTTGCAAAATACTATTGGTGCTTGCGATTTATCCGGGGAAGGTGTCTCTAAAATACTATTAACCGGCTCTGG TGGCCCCTTTTTAGAAAAGCCCTTAGCAGAATTTGCAGCGATCACCCCGGCACAGGCTGTTAAGCATCCCAATTGGTCGA TGGGTAAGAAAATATCAATAGACTCGGCCACCATGATGAATAAAGGGCTTGAGTATATTGAAGCGCGCTGGTTATTTAAT GCCAATAAAGAGCAGCTGCAGATAATAATACATCCTCAATCAGTCATTCATTCCATGGTGCAATATAAAGATGGTAGTGT GATAGCGCAGATGGGCAACCCTAATATGCGCATTCCGATTGCCTACGTCTTAGGGGGTGAGCAGCGTATCGAAAGTGGAA CTGATTTTTTAGATTTTTTTGCAGCGCCTGATTTTAGTTTTACCGCGCCTGATTTTGATCGTTACCCTTGCCTGAAATTG GCCATTGACGCTTGTTTTGAAGGACAGCAGTCAACCACTATTCTAAATGCAGCAAATGAAATTGCGGTTGAGGCTTTTTT AAATCAGACCATCAAATTCACCCAGATATCACAACTTGTTGAGCGTGTTTTAAACCAGCATGAAAGTGCCGCTATTGAGT CAGTCGAGCATTTATTAGAGATTGATACAGAGGCGAGGTTAAGCGCAAGTGAGATTATTAAACGGGATTATTTATGCTGA
Upstream 100 bases:
>100_bases TTTATTACCGGGCCATGGTGGCATTTTAGACAGGATAGATAGTTTAACCGCTGCTGTGCCGGTTTTTACCCTTATTTATC TATTTTGGTTAAGTTAGAAA
Downstream 100 bases:
>100_bases GTAGTTTATTGTATTTAGCTGGTGCGTTTTAAAACCACATGATGGTGTTGTTATTAAGTCAGTCGATCATTTTTAGGGAT TGATACAGAGGCGAGGTTAA
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 399; Mature: 399
Protein sequence:
>399_residues MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEISAKKLRGLLKRNNLSCHVLD DEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEVFLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQAL SPKLQNTIGACDLSGEGVSKILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFN ANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFFAAPDFSFTAPDFDRYPCLKL AIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLVERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC
Sequences:
>Translated_399_residues MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEISAKKLRGLLKRNNLSCHVLD DEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEVFLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQAL SPKLQNTIGACDLSGEGVSKILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFN ANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFFAAPDFSFTAPDFDRYPCLKL AIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLVERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC >Mature_399_residues MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEISAKKLRGLLKRNNLSCHVLD DEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEVFLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQAL SPKLQNTIGACDLSGEGVSKILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFN ANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFFAAPDFSFTAPDFDRYPCLKL AIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLVERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=395, Percent_Identity=55.1898734177215, Blast_Score=428, Evalue=1e-121,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_PSYIN (A1SYV7)
Other databases:
- EMBL: CP000510 - RefSeq: YP_944271.1 - ProteinModelPortal: A1SYV7 - SMR: A1SYV7 - STRING: A1SYV7 - GeneID: 4624774 - GenomeReviews: CP000510_GR - KEGG: pin:Ping_2970 - eggNOG: COG0743 - HOGENOM: HBG430762 - OMA: IHSMVEY - PhylomeDB: A1SYV7 - ProtClustDB: PRK05447 - BioCyc: PING357804:PING_2970-MONOMER - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 43383; Mature: 43383
Theoretical pI: Translated: 5.28; Mature: 5.28
Prosite motif: NA
Important sites: BINDING 125-125 BINDING 152-152 BINDING 186-186 BINDING 209-209 BINDING 231-231
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEI CCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCH SAKKLRGLLKRNNLSCHVLDDEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEV HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCEE FLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQALSPKLQNTIGACDLSGEGVSK EEECCCCCEEECHHHHHHHHHCCCEECCCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCEE ILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFN EEEECCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEC ANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFF CCCEEEEEEECCHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHHHHCCCHHHHHH AAPDFSFTAPDFDRYPCLKLAIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLV CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH ERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC HHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCC >Mature Secondary Structure MKKLAILGATGSIGDSTLSVCRSNPELYQITLLAASSSVDKMLALCREFTPLYVSMSSEI CCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEECCCH SAKKLRGLLKRNNLSCHVLDDEQRLLELLASDHVDSVMAAIVGAAGLKTTLAAVDAGKEV HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCEE FLANKEALVMSGALFIDAVKKSGAKLWPVDSEHNAIYQALSPKLQNTIGACDLSGEGVSK EEECCCCCEEECHHHHHHHHHCCCEECCCCCCHHHHHHHHCHHHHHHCCCCCCCCCCCEE ILLTGSGGPFLEKPLAEFAAITPAQAVKHPNWSMGKKISIDSATMMNKGLEYIEARWLFN EEEECCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEC ANKEQLQIIIHPQSVIHSMVQYKDGSVIAQMGNPNMRIPIAYVLGGEQRIESGTDFLDFF CCCEEEEEEECCHHHHHHHHHCCCCCEEEEECCCCEEEEEEEEECCHHHHHCCCHHHHHH AAPDFSFTAPDFDRYPCLKLAIDACFEGQQSTTILNAANEIAVEAFLNQTIKFTQISQLV CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHH ERVLNQHESAAIESVEHLLEIDTEARLSASEIIKRDYLC HHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA