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The map label for this gene is siaT [H]

Identifier: 119946556

GI number: 119946556

Start: 3619155

End: 3620477

Strand: Direct

Name: siaT [H]

Synonym: Ping_2935

Alternate gene names: 119946556

Gene position: 3619155-3620477 (Clockwise)

Preceding gene: 119946555

Following gene: 119946557

Centisome position: 79.37

GC content: 45.88

Gene sequence:

>1323_bases
ATGTTTGATTTATCCGCTATTGGCATAGGCTATGGCAGTTTATTAATGTTAGTGATGATGATAGCCCTGCTGTTAACCGG
CATGCAGCTTGCGTTTGTGACCGGTTTTGTGGCGCTATTTTTCACTATTGGCTGGTTTGGAATTGATGCGCTGCCTTTGG
TGACGAGTCGTTTATATAGCTTTGTTGATAGTTATATTTTTCTTGCTGTCCCTATGTTTGTATTGATGGCCGCACTGCTG
GACCGATCCGGTATTGCCCATGACCTTTTTGAGGCGATGAAATTATTTGGCAAACGTCTGCGCGGTGGTGTGGCGGTTCA
GACTTTACTGGTCGCGGTTATATTGGCTTCTATGTCCGGTGTTATCGGTGGTGAAACCGTGTTACTGGGTATTCTTGCGC
TGCCGCAGATGCTGCGTTTAGGTTATGATCGTAAGTTGGCTATTGGGGTCACCTGTGCCGGCGGCGCATTAGGGACGATG
CTGCCGCCCAGTATAGTACTAATTATTTATGGTTTAACGGCCAGTGTCTCTATCGGCGATCTGTTTAAAGCGTCGTTCTT
ACCAGCTTTGATACTCGCCGTCTTCTATATATTGTATGTGTTAATACGCTGTAAAATAAATCCATCCCTAGCACCTATAC
CCAGTGCAGAAGAATTGGCTAAAGATGCCGAAACACAACCGAATTTTTTCAAGGCGCTGTTATTCCCGTTATTATCGGTT
CTCGTTGTATTAGGCAGTATCTATACCGGCGTTGCATCGGTCACCGAAGCATCGGCCCTCGGTGTTGTCGGTATTATAAT
CAGTACCTGGATTCGTAAAGAGCTTTGTTTTGCAATGCTGAAAGATGCAGCGATTGCGACCATGAAAACCTGCGGTATGA
TCATCTGGATAGGGATAGGTGCAACCGCCTTAGTAGGTGTGTACAACCTGATGGGCGGCATTGATTTTGTGGAAGTGACT
ATATTGTCCCTCAGTGGCGGAAATGCAACGGCTACCCTGCTGATTATGATGGGTATCTTATTAGTGTTAGGCATGTTCCT
TGATTGGGTGGGTGTCGCGTTATTAACCATGCCTATTTTTGTGCCCATTATTGTCGGTTTAGGGATGGATCCCGTTTGGT
TTGGTGTGGTTTTCTGCCTTAATATGCAGGTATCATTCCTTTCACCTCCCTTTGGCCCCGCCGCCTTCTATTTGAAATCC
GTGGCACCAAAAGATATCAGTCTGGGGGAAATATTCAGTGCACTGGTGCCTTTTATCTGCCTGCAAATTGTCACCCTTAG
TTTGGTTATCATTTTCCCCGTTCTCGCTTTATGGTGGAGATAA

Upstream 100 bases:

>100_bases
GCTCTATTAAAAGCAATTATTGTTATTGCCTTTTGTATTCTTACTATTCAATTTTTACTGCATTTGATTGCTGAAATCAA
AGTGCTAAGGAAGCATTCTC

Downstream 100 bases:

>100_bases
TGGCTAATATTAATGGGGCTCATTCATCCTTTACGGGCGTAAAAATAGTCATAATGGGGGTCTCAGGCTGTGGCAAAAGT
TCAATCGGCAGCAAGCTTGC

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MFDLSAIGIGYGSLLMLVMMIALLLTGMQLAFVTGFVALFFTIGWFGIDALPLVTSRLYSFVDSYIFLAVPMFVLMAALL
DRSGIAHDLFEAMKLFGKRLRGGVAVQTLLVAVILASMSGVIGGETVLLGILALPQMLRLGYDRKLAIGVTCAGGALGTM
LPPSIVLIIYGLTASVSIGDLFKASFLPALILAVFYILYVLIRCKINPSLAPIPSAEELAKDAETQPNFFKALLFPLLSV
LVVLGSIYTGVASVTEASALGVVGIIISTWIRKELCFAMLKDAAIATMKTCGMIIWIGIGATALVGVYNLMGGIDFVEVT
ILSLSGGNATATLLIMMGILLVLGMFLDWVGVALLTMPIFVPIIVGLGMDPVWFGVVFCLNMQVSFLSPPFGPAAFYLKS
VAPKDISLGEIFSALVPFICLQIVTLSLVIIFPVLALWWR

Sequences:

>Translated_440_residues
MFDLSAIGIGYGSLLMLVMMIALLLTGMQLAFVTGFVALFFTIGWFGIDALPLVTSRLYSFVDSYIFLAVPMFVLMAALL
DRSGIAHDLFEAMKLFGKRLRGGVAVQTLLVAVILASMSGVIGGETVLLGILALPQMLRLGYDRKLAIGVTCAGGALGTM
LPPSIVLIIYGLTASVSIGDLFKASFLPALILAVFYILYVLIRCKINPSLAPIPSAEELAKDAETQPNFFKALLFPLLSV
LVVLGSIYTGVASVTEASALGVVGIIISTWIRKELCFAMLKDAAIATMKTCGMIIWIGIGATALVGVYNLMGGIDFVEVT
ILSLSGGNATATLLIMMGILLVLGMFLDWVGVALLTMPIFVPIIVGLGMDPVWFGVVFCLNMQVSFLSPPFGPAAFYLKS
VAPKDISLGEIFSALVPFICLQIVTLSLVIIFPVLALWWR
>Mature_440_residues
MFDLSAIGIGYGSLLMLVMMIALLLTGMQLAFVTGFVALFFTIGWFGIDALPLVTSRLYSFVDSYIFLAVPMFVLMAALL
DRSGIAHDLFEAMKLFGKRLRGGVAVQTLLVAVILASMSGVIGGETVLLGILALPQMLRLGYDRKLAIGVTCAGGALGTM
LPPSIVLIIYGLTASVSIGDLFKASFLPALILAVFYILYVLIRCKINPSLAPIPSAEELAKDAETQPNFFKALLFPLLSV
LVVLGSIYTGVASVTEASALGVVGIIISTWIRKELCFAMLKDAAIATMKTCGMIIWIGIGATALVGVYNLMGGIDFVEVT
ILSLSGGNATATLLIMMGILLVLGMFLDWVGVALLTMPIFVPIIVGLGMDPVWFGVVFCLNMQVSFLSPPFGPAAFYLKS
VAPKDISLGEIFSALVPFICLQIVTLSLVIIFPVLALWWR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=374, Percent_Identity=27.0053475935829, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46933; Mature: 46933

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDLSAIGIGYGSLLMLVMMIALLLTGMQLAFVTGFVALFFTIGWFGIDALPLVTSRLYS
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDSYIFLAVPMFVLMAALLDRSGIAHDLFEAMKLFGKRLRGGVAVQTLLVAVILASMSG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
VIGGETVLLGILALPQMLRLGYDRKLAIGVTCAGGALGTMLPPSIVLIIYGLTASVSIGD
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHCCCHHHHHHHHHHHCCCHHHH
LFKASFLPALILAVFYILYVLIRCKINPSLAPIPSAEELAKDAETQPNFFKALLFPLLSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LVVLGSIYTGVASVTEASALGVVGIIISTWIRKELCFAMLKDAAIATMKTCGMIIWIGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
ATALVGVYNLMGGIDFVEVTILSLSGGNATATLLIMMGILLVLGMFLDWVGVALLTMPIF
HHHHHHHHHHHCCCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIIVGLGMDPVWFGVVFCLNMQVSFLSPPFGPAAFYLKSVAPKDISLGEIFSALVPFIC
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LQIVTLSLVIIFPVLALWWR
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFDLSAIGIGYGSLLMLVMMIALLLTGMQLAFVTGFVALFFTIGWFGIDALPLVTSRLYS
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDSYIFLAVPMFVLMAALLDRSGIAHDLFEAMKLFGKRLRGGVAVQTLLVAVILASMSG
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
VIGGETVLLGILALPQMLRLGYDRKLAIGVTCAGGALGTMLPPSIVLIIYGLTASVSIGD
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHCCCHHHHHHHHHHHCCCHHHH
LFKASFLPALILAVFYILYVLIRCKINPSLAPIPSAEELAKDAETQPNFFKALLFPLLSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LVVLGSIYTGVASVTEASALGVVGIIISTWIRKELCFAMLKDAAIATMKTCGMIIWIGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
ATALVGVYNLMGGIDFVEVTILSLSGGNATATLLIMMGILLVLGMFLDWVGVALLTMPIF
HHHHHHHHHHHCCCHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIIVGLGMDPVWFGVVFCLNMQVSFLSPPFGPAAFYLKSVAPKDISLGEIFSALVPFIC
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LQIVTLSLVIIFPVLALWWR
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]