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The map label for this gene is gntK [H]

Identifier: 119946557

GI number: 119946557

Start: 3620477

End: 3621010

Strand: Direct

Name: gntK [H]

Synonym: Ping_2936

Alternate gene names: 119946557

Gene position: 3620477-3621010 (Clockwise)

Preceding gene: 119946556

Following gene: 119946558

Centisome position: 79.4

GC content: 39.89

Gene sequence:

>534_bases
ATGGCTAATATTAATGGGGCTCATTCATCCTTTACGGGCGTAAAAATAGTCATAATGGGGGTCTCAGGCTGTGGCAAAAG
TTCAATCGGCAGCAAGCTTGCTGAGCAATTAGGTCTGACTTTCTTTGATGGCGATGATTATCATTGCACTGAGAATGTTG
ACAAGATGAGCCAAGGTATTCCGCTTACGGATAAGGACAGGCAGGGCTGGTTATCAAGCTTGAATAACTTGTTTCAGCAA
CGCGCTGAAGGGGTTGTGGCTTGTTCAGCACTAACACCTGAATACAGACGGATTTTAAGACACAATAATAAAGAGTTGCT
GTTCGTTTATTTACAAGGGGATTTTGATACGATTTGGCAGCGTCATCAAAATAGAACCGACCATTATTTTAAAGGTAAAA
CCCTGCTTGAAAATCAGTTTGCCACCTTAGTTGAACCCAATGCTTCGGAAGCGTTAATTATTGACATCCGTCAAAATGTG
AGTGAAATTGTAGCGGATATTATTCAAAAACTAAGTGATTTAAACAATAAATAA

Upstream 100 bases:

>100_bases
TGGGGGAAATATTCAGTGCACTGGTGCCTTTTATCTGCCTGCAAATTGTCACCCTTAGTTTGGTTATCATTTTCCCCGTT
CTCGCTTTATGGTGGAGATA

Downstream 100 bases:

>100_bases
AATTTTCCTAATCTATCGAAACACTGAGAGCCGAATGAAGACTAAAATAGATATTGCCGTGATAGGCTTAGGCGTGATGG
GTGCCAATATGGCACTAAAT

Product: carbohydrate kinase, thermoresistant glucokinase family protein

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MANINGAHSSFTGVKIVIMGVSGCGKSSIGSKLAEQLGLTFFDGDDYHCTENVDKMSQGIPLTDKDRQGWLSSLNNLFQQ
RAEGVVACSALTPEYRRILRHNNKELLFVYLQGDFDTIWQRHQNRTDHYFKGKTLLENQFATLVEPNASEALIIDIRQNV
SEIVADIIQKLSDLNNK

Sequences:

>Translated_177_residues
MANINGAHSSFTGVKIVIMGVSGCGKSSIGSKLAEQLGLTFFDGDDYHCTENVDKMSQGIPLTDKDRQGWLSSLNNLFQQ
RAEGVVACSALTPEYRRILRHNNKELLFVYLQGDFDTIWQRHQNRTDHYFKGKTLLENQFATLVEPNASEALIIDIRQNV
SEIVADIIQKLSDLNNK
>Mature_176_residues
ANINGAHSSFTGVKIVIMGVSGCGKSSIGSKLAEQLGLTFFDGDDYHCTENVDKMSQGIPLTDKDRQGWLSSLNNLFQQR
AEGVVACSALTPEYRRILRHNNKELLFVYLQGDFDTIWQRHQNRTDHYFKGKTLLENQFATLVEPNASEALIIDIRQNVS
EIVADIIQKLSDLNNK

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=179, Percent_Identity=41.8994413407821, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI87082265, Length=159, Percent_Identity=45.9119496855346, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1790719, Length=160, Percent_Identity=43.75, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25146487, Length=180, Percent_Identity=40, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320454, Length=171, Percent_Identity=32.7485380116959, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19862; Mature: 19730

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANINGAHSSFTGVKIVIMGVSGCGKSSIGSKLAEQLGLTFFDGDDYHCTENVDKMSQGI
CCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCC
PLTDKDRQGWLSSLNNLFQQRAEGVVACSALTPEYRRILRHNNKELLFVYLQGDFDTIWQ
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEEEECCHHHHHH
RHQNRTDHYFKGKTLLENQFATLVEPNASEALIIDIRQNVSEIVADIIQKLSDLNNK
HHCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANINGAHSSFTGVKIVIMGVSGCGKSSIGSKLAEQLGLTFFDGDDYHCTENVDKMSQGI
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCC
PLTDKDRQGWLSSLNNLFQQRAEGVVACSALTPEYRRILRHNNKELLFVYLQGDFDTIWQ
CCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEEEECCHHHHHH
RHQNRTDHYFKGKTLLENQFATLVEPNASEALIIDIRQNVSEIVADIIQKLSDLNNK
HHCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]