Click here to switch to the map view.

The map label for this gene is aceE [H]

Identifier: 119946548

GI number: 119946548

Start: 3610291

End: 3612951

Strand: Reverse

Name: aceE [H]

Synonym: Ping_2927

Alternate gene names: 119946548

Gene position: 3612951-3610291 (Counterclockwise)

Preceding gene: 119946549

Following gene: 119946547

Centisome position: 79.24

GC content: 43.25

Gene sequence:

>2661_bases
ATGACTGACATCCTAAATGATATTGATGCACAAGAAACGTCAGAATGGCTTGATGCCCTGACAACAATTCTTGAAGATGA
AGGGACTGAGCGTGCCCAGTTCATCATTAAAAAAGTAACCGAACAAGCCCGTAAAGAGGGGGTTAAGTTACCCACGGATA
TTAATACAAATTATATTAATACTATTCCGCTTGCACAGCAGCCGGACTATCCTGGTGATATCAAAATAGAACGTCGCATT
CGTTCTATTATCCGCTGGAATGCGATCATGATCGTGATGCGTGCTTCTAAAAAAGAGTTGGACTTAGGGGGGCACATGGC
CTCTTACCAGTCTGCAGCAGCATTCTACGAAGTCTGTTTTAACCATTTCTTTCGTGCAGCGAATGAAACCGATGGCGGTG
ATTTAGTTTATTACCAGGGGCATATCTCTCCCGGTATCTATGCGCGTGCATTTCTTGAAGGTCGTTTAAGCGCTGACCAA
CTTGATCATTTCCGCCAGGAAGTTGATGGCAAAGGGTTACCGTCCTATCCACATCCGAAACTATTACCTGAATTTTGGCA
GTTCCCTACCGTTTCGATGGGACTTGGTCCAATTGCTGCTATTTATCAGGCACGTTTCCTAAAATATCTTGATGGTCGTG
GTTTAAAACAAACGGCTAATCAGCGTGTTTATGCTTTTCTGGGTGACGGTGAGATGGATGAGCCAGAATCGCGTGGTTCT
TTATCATTTGCATCGCGTGAAAAACTCGATAACTTGTGTTTCTTAATTAACTGTAATTTACAGCGTTTAGATGGCCCGGT
AATGGGTAACGGCAGCATTATTCAAGAACTTGAAGGCCTATTTCATGGTGCTGGCTGGAATGTTGTTAAAGTTATCTGGG
GTGGCAACTGGGATTCTCTGCTTGCACAGGATTCATCGGGTAAACTGCTGCAATTAATGGAAGAGACCGTTGATGGTGAT
TACCAAACCTTTAAATCAAAAGATGGTGCTTACGTTCGTGAACATTTCTTTGGTAAATATCCTGAAACAGCCGCACTAGT
TGCAACTTGGACAGATGAAGAAATCTTTGCATTGAAGCGCGGTGGTCATGATTCATCTAAACTCTATGCCGCCTTTAAAA
ATGCTCAGGAGACGCAGGGCAAACCAACGGTTATCTTAGCTAAAACAGTTAAAGGTTACGGTATGGGTGCAGCGGCTGAG
GGCAAAAACATTGCTCACGGCGTGAAGAAAATGAACGAAACACATATTCAAACCTTACGTGATCGTTTAGGCCTGCAGGA
CCTGTTAAGTGATGAGAATGCGTCAACACTACCTTACTTAACACTGGAAGAAGGCTCGGAAGAATACAAATATTTACACG
GTCATCGTGAAGCACTATTAGGTTATACTCCTAAACGTTCTACTAAGTTTTCTGGAAAACTTGAGGTACCGTCGCTTGAG
AAATTCGCACCGCTGTTACAAGAGCAAAAACGTGAAATCTCAACCACCATGGCTTATGTGCGTATTTTAAACCTTTTATT
AAAAGACAAAAGTATCGGTAAAAATATTGTCCCGATCATTGCCGATGAAGGCCGTACTTTTGGTATGGAAGGTTTATTCC
GTCAAGTCGGTATCTACAATCCGGATGGCCAGGAATACACCCCGGAAGATCGCGGAGTTGTTTCTTACTACAAAGAAACA
AAATCGGGTCAGGTACTCCAAGAAGGTATCAATGAATTAGGTTCAATGTCTTCTTGGGTGGCAGCTGCCACGTCTTATAG
CACCAATGATTTACCGATGATTCCATTCTACATCTACTACTCTATGTTTGGTTTTCAGCGTGTTGGTGATATGGCATGGA
TGGCGGGTGACCAACAGGCTCGTGGTTTCCTAATCGGTGCGACCGCTGGTCGTACAACGCTAAATGGCGAAGGCTTACAG
CATGAAGATGGTCACAGTCACATTCAGGCTAATACTATCCCTAACTGTATCTCTTATGACCCGACTTTTGTGTACGAACT
GGCCGTTATTATTCAAGATGGTATTGAGCGTATGTACGGTGAGAAGCAGGAGAATGTTTTCTACTACTTAACGGTGATGA
ATGAAAACTACGCCATGCCGGCAATGCCTGAAGGCGCTGAAGAAGGTATTCGTAAAGGTATCTATAAACTTCAATCGCAC
ACGGGTAGTAATAAAGTACAGTTATTAAGTTCAGGTACGATCATGAATGAAGTACGCAGAGCGGCTGTCATTCTAAGTGA
AGAATATGACGTAGCCTCTGATATTTTCTCGGTGACTTCATTTAATGAATTAACCCGTGAAGGTCAGGATGCAGAGCGAT
ACAATATGCTTAACCCGGAAGCTGAGCAAAAAGTCGCTTACATTACCCAAATATTAGGTGATGAGCCAACGATTGCGGCA
ACGGATTACATGAAAAACTATGCTGAGCAAGTACGTGCCTTTGTTCCAAGTGATTCCTATAAAGTGCTTGGTACCGATGG
TTTCGGTCGCAGTGACAGTCGTGAAAATTTACGTCGTCACTTTGAAGTGAATGCAGGTTATGTTGTTGTTGCGGCATTAG
CTGAGCTTGCCAAACGTGGTGATATCGAACGTTCAGTCGTCACCCAAGCCATTGCTAAATTTGCTATCGATGTAAACAAA
ACCAACCCATTATTTGCGTAA

Upstream 100 bases:

>100_bases
CAAAACGTGTTTTAAAACAGGTAATGGTTAATCTAAATAGTTATACATCAAACGCTTAACCTTAGGGTTGAGATTTTCTA
GTGATAAGAAGGAAAGTGTC

Downstream 100 bases:

>100_bases
ATTAAATGCGCTGTTATTAAACAATAACAGCGTCTTTTATTGATTAGGAAAATTATTATGTCTGAATTAAAAGAATTTTT
ACTGCCTGATATTGGTGCCG

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 886; Mature: 885

Protein sequence:

>886_residues
MTDILNDIDAQETSEWLDALTTILEDEGTERAQFIIKKVTEQARKEGVKLPTDINTNYINTIPLAQQPDYPGDIKIERRI
RSIIRWNAIMIVMRASKKELDLGGHMASYQSAAAFYEVCFNHFFRAANETDGGDLVYYQGHISPGIYARAFLEGRLSADQ
LDHFRQEVDGKGLPSYPHPKLLPEFWQFPTVSMGLGPIAAIYQARFLKYLDGRGLKQTANQRVYAFLGDGEMDEPESRGS
LSFASREKLDNLCFLINCNLQRLDGPVMGNGSIIQELEGLFHGAGWNVVKVIWGGNWDSLLAQDSSGKLLQLMEETVDGD
YQTFKSKDGAYVREHFFGKYPETAALVATWTDEEIFALKRGGHDSSKLYAAFKNAQETQGKPTVILAKTVKGYGMGAAAE
GKNIAHGVKKMNETHIQTLRDRLGLQDLLSDENASTLPYLTLEEGSEEYKYLHGHREALLGYTPKRSTKFSGKLEVPSLE
KFAPLLQEQKREISTTMAYVRILNLLLKDKSIGKNIVPIIADEGRTFGMEGLFRQVGIYNPDGQEYTPEDRGVVSYYKET
KSGQVLQEGINELGSMSSWVAAATSYSTNDLPMIPFYIYYSMFGFQRVGDMAWMAGDQQARGFLIGATAGRTTLNGEGLQ
HEDGHSHIQANTIPNCISYDPTFVYELAVIIQDGIERMYGEKQENVFYYLTVMNENYAMPAMPEGAEEGIRKGIYKLQSH
TGSNKVQLLSSGTIMNEVRRAAVILSEEYDVASDIFSVTSFNELTREGQDAERYNMLNPEAEQKVAYITQILGDEPTIAA
TDYMKNYAEQVRAFVPSDSYKVLGTDGFGRSDSRENLRRHFEVNAGYVVVAALAELAKRGDIERSVVTQAIAKFAIDVNK
TNPLFA

Sequences:

>Translated_886_residues
MTDILNDIDAQETSEWLDALTTILEDEGTERAQFIIKKVTEQARKEGVKLPTDINTNYINTIPLAQQPDYPGDIKIERRI
RSIIRWNAIMIVMRASKKELDLGGHMASYQSAAAFYEVCFNHFFRAANETDGGDLVYYQGHISPGIYARAFLEGRLSADQ
LDHFRQEVDGKGLPSYPHPKLLPEFWQFPTVSMGLGPIAAIYQARFLKYLDGRGLKQTANQRVYAFLGDGEMDEPESRGS
LSFASREKLDNLCFLINCNLQRLDGPVMGNGSIIQELEGLFHGAGWNVVKVIWGGNWDSLLAQDSSGKLLQLMEETVDGD
YQTFKSKDGAYVREHFFGKYPETAALVATWTDEEIFALKRGGHDSSKLYAAFKNAQETQGKPTVILAKTVKGYGMGAAAE
GKNIAHGVKKMNETHIQTLRDRLGLQDLLSDENASTLPYLTLEEGSEEYKYLHGHREALLGYTPKRSTKFSGKLEVPSLE
KFAPLLQEQKREISTTMAYVRILNLLLKDKSIGKNIVPIIADEGRTFGMEGLFRQVGIYNPDGQEYTPEDRGVVSYYKET
KSGQVLQEGINELGSMSSWVAAATSYSTNDLPMIPFYIYYSMFGFQRVGDMAWMAGDQQARGFLIGATAGRTTLNGEGLQ
HEDGHSHIQANTIPNCISYDPTFVYELAVIIQDGIERMYGEKQENVFYYLTVMNENYAMPAMPEGAEEGIRKGIYKLQSH
TGSNKVQLLSSGTIMNEVRRAAVILSEEYDVASDIFSVTSFNELTREGQDAERYNMLNPEAEQKVAYITQILGDEPTIAA
TDYMKNYAEQVRAFVPSDSYKVLGTDGFGRSDSRENLRRHFEVNAGYVVVAALAELAKRGDIERSVVTQAIAKFAIDVNK
TNPLFA
>Mature_885_residues
TDILNDIDAQETSEWLDALTTILEDEGTERAQFIIKKVTEQARKEGVKLPTDINTNYINTIPLAQQPDYPGDIKIERRIR
SIIRWNAIMIVMRASKKELDLGGHMASYQSAAAFYEVCFNHFFRAANETDGGDLVYYQGHISPGIYARAFLEGRLSADQL
DHFRQEVDGKGLPSYPHPKLLPEFWQFPTVSMGLGPIAAIYQARFLKYLDGRGLKQTANQRVYAFLGDGEMDEPESRGSL
SFASREKLDNLCFLINCNLQRLDGPVMGNGSIIQELEGLFHGAGWNVVKVIWGGNWDSLLAQDSSGKLLQLMEETVDGDY
QTFKSKDGAYVREHFFGKYPETAALVATWTDEEIFALKRGGHDSSKLYAAFKNAQETQGKPTVILAKTVKGYGMGAAAEG
KNIAHGVKKMNETHIQTLRDRLGLQDLLSDENASTLPYLTLEEGSEEYKYLHGHREALLGYTPKRSTKFSGKLEVPSLEK
FAPLLQEQKREISTTMAYVRILNLLLKDKSIGKNIVPIIADEGRTFGMEGLFRQVGIYNPDGQEYTPEDRGVVSYYKETK
SGQVLQEGINELGSMSSWVAAATSYSTNDLPMIPFYIYYSMFGFQRVGDMAWMAGDQQARGFLIGATAGRTTLNGEGLQH
EDGHSHIQANTIPNCISYDPTFVYELAVIIQDGIERMYGEKQENVFYYLTVMNENYAMPAMPEGAEEGIRKGIYKLQSHT
GSNKVQLLSSGTIMNEVRRAAVILSEEYDVASDIFSVTSFNELTREGQDAERYNMLNPEAEQKVAYITQILGDEPTIAAT
DYMKNYAEQVRAFVPSDSYKVLGTDGFGRSDSRENLRRHFEVNAGYVVVAALAELAKRGDIERSVVTQAIAKFAIDVNKT
NPLFA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=883, Percent_Identity=70.3284258210646, Blast_Score=1337, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 99060; Mature: 98929

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDILNDIDAQETSEWLDALTTILEDEGTERAQFIIKKVTEQARKEGVKLPTDINTNYIN
CCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
TIPLAQQPDYPGDIKIERRIRSIIRWNAIMIVMRASKKELDLGGHMASYQSAAAFYEVCF
ECCCCCCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
NHFFRAANETDGGDLVYYQGHISPGIYARAFLEGRLSADQLDHFRQEVDGKGLPSYPHPK
HHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
LLPEFWQFPTVSMGLGPIAAIYQARFLKYLDGRGLKQTANQRVYAFLGDGEMDEPESRGS
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCCCCCC
LSFASREKLDNLCFLINCNLQRLDGPVMGNGSIIQELEGLFHGAGWNVVKVIWGGNWDSL
CCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHH
LAQDSSGKLLQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVATWTDEEIFALKR
HCCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCHHHHHHC
GGHDSSKLYAAFKNAQETQGKPTVILAKTVKGYGMGAAAEGKNIAHGVKKMNETHIQTLR
CCCCHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DRLGLQDLLSDENASTLPYLTLEEGSEEYKYLHGHREALLGYTPKRSTKFSGKLEVPSLE
HHCCHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
KFAPLLQEQKREISTTMAYVRILNLLLKDKSIGKNIVPIIADEGRTFGMEGLFRQVGIYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCCC
PDGQEYTPEDRGVVSYYKETKSGQVLQEGINELGSMSSWVAAATSYSTNDLPMIPFYIYY
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHH
SMFGFQRVGDMAWMAGDQQARGFLIGATAGRTTLNGEGLQHEDGHSHIQANTIPNCISYD
HHHHHHHHCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
PTFVYELAVIIQDGIERMYGEKQENVFYYLTVMNENYAMPAMPEGAEEGIRKGIYKLQSH
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
TGSNKVQLLSSGTIMNEVRRAAVILSEEYDVASDIFSVTSFNELTREGQDAERYNMLNPE
CCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCH
AEQKVAYITQILGDEPTIAATDYMKNYAEQVRAFVPSDSYKVLGTDGFGRSDSRENLRRH
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
FEVNAGYVVVAALAELAKRGDIERSVVTQAIAKFAIDVNKTNPLFA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCC
>Mature Secondary Structure 
TDILNDIDAQETSEWLDALTTILEDEGTERAQFIIKKVTEQARKEGVKLPTDINTNYIN
CCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE
TIPLAQQPDYPGDIKIERRIRSIIRWNAIMIVMRASKKELDLGGHMASYQSAAAFYEVCF
ECCCCCCCCCCCCEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
NHFFRAANETDGGDLVYYQGHISPGIYARAFLEGRLSADQLDHFRQEVDGKGLPSYPHPK
HHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCC
LLPEFWQFPTVSMGLGPIAAIYQARFLKYLDGRGLKQTANQRVYAFLGDGEMDEPESRGS
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCCCCCC
LSFASREKLDNLCFLINCNLQRLDGPVMGNGSIIQELEGLFHGAGWNVVKVIWGGNWDSL
CCHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHH
LAQDSSGKLLQLMEETVDGDYQTFKSKDGAYVREHFFGKYPETAALVATWTDEEIFALKR
HCCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCEEEEEEECCCHHHHHHC
GGHDSSKLYAAFKNAQETQGKPTVILAKTVKGYGMGAAAEGKNIAHGVKKMNETHIQTLR
CCCCHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DRLGLQDLLSDENASTLPYLTLEEGSEEYKYLHGHREALLGYTPKRSTKFSGKLEVPSLE
HHCCHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
KFAPLLQEQKREISTTMAYVRILNLLLKDKSIGKNIVPIIADEGRTFGMEGLFRQVGIYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCCC
PDGQEYTPEDRGVVSYYKETKSGQVLQEGINELGSMSSWVAAATSYSTNDLPMIPFYIYY
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHH
SMFGFQRVGDMAWMAGDQQARGFLIGATAGRTTLNGEGLQHEDGHSHIQANTIPNCISYD
HHHHHHHHCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
PTFVYELAVIIQDGIERMYGEKQENVFYYLTVMNENYAMPAMPEGAEEGIRKGIYKLQSH
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHC
TGSNKVQLLSSGTIMNEVRRAAVILSEEYDVASDIFSVTSFNELTREGQDAERYNMLNPE
CCCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCH
AEQKVAYITQILGDEPTIAATDYMKNYAEQVRAFVPSDSYKVLGTDGFGRSDSRENLRRH
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHH
FEVNAGYVVVAALAELAKRGDIERSVVTQAIAKFAIDVNKTNPLFA
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]