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The map label for this gene is cdd [H]

Identifier: 119946491

GI number: 119946491

Start: 3547276

End: 3547683

Strand: Direct

Name: cdd [H]

Synonym: Ping_2867

Alternate gene names: 119946491

Gene position: 3547276-3547683 (Clockwise)

Preceding gene: 119946490

Following gene: 119946492

Centisome position: 77.8

GC content: 41.18

Gene sequence:

>408_bases
ATGCAAAAAAACTATTTTACTGAACTTAAAAAACTACTTGATAATGCTCAAGCGCCCTACTCAGGATTTAATGTTGCAGC
CATTGTAATAACCCGTAACGGTAATCTTTATAAAGGCGTCAATGTTGAATCCGCCGCGTACCCGACCACTATCTGTGCTG
AGCGTAATGCTATTCACACGGCTGTTACTGAAGGAATGAAGAAAGGTGAGGTTAAAGAAATTCACCTAATCGCCCGTAAC
GCAGCAAAAGCGCTTATTAAAGCACAGCCCTGTGGTGGGTGCCGACAAGTGATTGCTGAACAATCAGGCAATGATGCCAT
TGTTTACAGTTATGCTTCAGCGCTCGAAATAGAGCAGCATAGTATCAATGAGTTATTACCCTTTGCTTTTTTAGGTGATG
ATTTATAA

Upstream 100 bases:

>100_bases
ACCGCAAGCGATCAGGATCATTGTTTATATCTTAATAAAATGGGCTTTGCTGCACAGCCGGACAATCAATCACAAACCTA
TATAAAAAGGCTCTAACATT

Downstream 100 bases:

>100_bases
CAGTCCAACAGTTCTCAATTTACACAGGAGTTTTATTATGTCAGATGTATTTCATTTAGGCCTAAGCAAAAAAATGCTCG
ATGGTGCGAGCCTCGCAATA

Product: CMP/dCMP deaminase, zinc-binding

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MQKNYFTELKKLLDNAQAPYSGFNVAAIVITRNGNLYKGVNVESAAYPTTICAERNAIHTAVTEGMKKGEVKEIHLIARN
AAKALIKAQPCGGCRQVIAEQSGNDAIVYSYASALEIEQHSINELLPFAFLGDDL

Sequences:

>Translated_135_residues
MQKNYFTELKKLLDNAQAPYSGFNVAAIVITRNGNLYKGVNVESAAYPTTICAERNAIHTAVTEGMKKGEVKEIHLIARN
AAKALIKAQPCGGCRQVIAEQSGNDAIVYSYASALEIEQHSINELLPFAFLGDDL
>Mature_135_residues
MQKNYFTELKKLLDNAQAPYSGFNVAAIVITRNGNLYKGVNVESAAYPTTICAERNAIHTAVTEGMKKGEVKEIHLIARN
AAKALIKAQPCGGCRQVIAEQSGNDAIVYSYASALEIEQHSINELLPFAFLGDDL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=121, Percent_Identity=40.495867768595, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17540514, Length=123, Percent_Identity=39.8373983739837, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=123, Percent_Identity=35.7723577235772, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323274, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=35.9375, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14673; Mature: 14673

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNYFTELKKLLDNAQAPYSGFNVAAIVITRNGNLYKGVNVESAAYPTTICAERNAIHT
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCHHHCCCCHHHH
AVTEGMKKGEVKEIHLIARNAAKALIKAQPCGGCRQVIAEQSGNDAIVYSYASALEIEQH
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHH
SINELLPFAFLGDDL
HHHHHCCHHHCCCCC
>Mature Secondary Structure
MQKNYFTELKKLLDNAQAPYSGFNVAAIVITRNGNLYKGVNVESAAYPTTICAERNAIHT
CCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCHHHCCCCHHHH
AVTEGMKKGEVKEIHLIARNAAKALIKAQPCGGCRQVIAEQSGNDAIVYSYASALEIEQH
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHH
SINELLPFAFLGDDL
HHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]