BacMap

Definition	Psychromonas ingrahamii 37, complete genome.
Accession	NC_008709
Length	4,559,598

Click here to switch to the map view.

The map label for this gene is butA [H]

Identifier: 119946404

GI number: 119946404

Start: 3418097

End: 3418900

Strand: Reverse

Name: butA [H]

Synonym: Ping_2778

Alternate gene names: 119946404

Gene position: 3418900-3418097 (Counterclockwise)

Preceding gene: 119946405

Following gene: 119946398

Centisome position: 74.98

GC content: 40.17

Gene sequence:

>804_bases
ATGGATAAAACAAGATTAGCTTCAAAAAACATTCTGATTACTGGTTCAGCAAGAGGAATGGGGGCTGCAACGGCTGAAAA
TTACGCCGCACAAGGTGCAAAAGTGTGTATTGCCGATTTAAATATCGATGGTTGTAATGAAGTGGTTGCACGTATTATAG
CCAATGGTGGCCAGGCAATAGCAGTGCAAATGGATGTGACTAATCGTGAATCTATTGCTGCTGGTGTACAAGCAACAGTT
GATGCTTTTGGTTCAATAAATGTCATGCTTAATAATGCCGGTATCAATAAACCATTAATGTTTATGGATATCACAGAAGA
GAATTGGCATCAAATTATGACCGTTAATGGTCTTGGTTGTTTAATGGGCATGCAGGAAGCAGCTCGTCAAATGATCAAAC
AAGGTCCACAAGATGAACCTTATAAAATCATTAATGTAGGGTCTATTCTTTCCCGTCAGGCTTTCGATGATGTTGTACCT
TATTCTTGCAGTAAACATGCTGTCTTAGCAATGATTAACGGCGGTGCTAAAGCGTTGGTTCAGCACAACATTACGGTTAA
TGGCTATGGTCCTGGTGTGGTTCGAACAGAATTGTGGGAACAGTTGGATAAAGACCTGGTCGCAATCGGTAAATTCAAAA
AAGAAGGTGAGTCTATGGATACATTAGCAGCTGACAGTATTCTTTTAGGTCGTTACTCTTACCCTGAAGATATTACAGGC
ACGGCTTCATTCCTTGCGAGTAAAGATTCAGATTACATGACGGGTCAATTAATTATGATTGATGGCGGCATGATAATGCA
ATAA

Upstream 100 bases:

>100_bases
AAAATTAACAATTTATTACATTGTTATTATTGACCTGTATTTTTGCTCTTTTACATAAATTATTTTTATGTGAATATTTT
ATTAAAAAGGAAAGTGTATT

Downstream 100 bases:

>100_bases
ATTCTATTTTTATCAAGTTGTTTTATCATATGGATATTGCTAGCTCATATTTTTAATTGTGATTATGAGCGAGTAATATC
CACTTTATCTAAACGTTAGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MDKTRLASKNILITGSARGMGAATAENYAAQGAKVCIADLNIDGCNEVVARIIANGGQAIAVQMDVTNRESIAAGVQATV
DAFGSINVMLNNAGINKPLMFMDITEENWHQIMTVNGLGCLMGMQEAARQMIKQGPQDEPYKIINVGSILSRQAFDDVVP
YSCSKHAVLAMINGGAKALVQHNITVNGYGPGVVRTELWEQLDKDLVAIGKFKKEGESMDTLAADSILLGRYSYPEDITG
TASFLASKDSDYMTGQLIMIDGGMIMQ

Sequences:

>Translated_267_residues
MDKTRLASKNILITGSARGMGAATAENYAAQGAKVCIADLNIDGCNEVVARIIANGGQAIAVQMDVTNRESIAAGVQATV
DAFGSINVMLNNAGINKPLMFMDITEENWHQIMTVNGLGCLMGMQEAARQMIKQGPQDEPYKIINVGSILSRQAFDDVVP
YSCSKHAVLAMINGGAKALVQHNITVNGYGPGVVRTELWEQLDKDLVAIGKFKKEGESMDTLAADSILLGRYSYPEDITG
TASFLASKDSDYMTGQLIMIDGGMIMQ
>Mature_267_residues
MDKTRLASKNILITGSARGMGAATAENYAAQGAKVCIADLNIDGCNEVVARIIANGGQAIAVQMDVTNRESIAAGVQATV
DAFGSINVMLNNAGINKPLMFMDITEENWHQIMTVNGLGCLMGMQEAARQMIKQGPQDEPYKIINVGSILSRQAFDDVVP
YSCSKHAVLAMINGGAKALVQHNITVNGYGPGVVRTELWEQLDKDLVAIGKFKKEGESMDTLAADSILLGRYSYPEDITG
TASFLASKDSDYMTGQLIMIDGGMIMQ

Specific function: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=29.2307692307692, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI15277342, Length=272, Percent_Identity=26.8382352941176, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=25.5725190839695, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=22.9571984435798, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=238, Percent_Identity=27.7310924369748, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI109715829, Length=208, Percent_Identity=28.8461538461538, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=264, Percent_Identity=26.1363636363636, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4504505, Length=221, Percent_Identity=29.8642533936652, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=25.0965250965251, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=27.0588235294118, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790717, Length=265, Percent_Identity=33.2075471698113, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=30.46875, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=31.6793893129771, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=29.2134831460674, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787335, Length=256, Percent_Identity=28.125, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=26.1538461538462, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787905, Length=271, Percent_Identity=26.1992619926199, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=24.4186046511628, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=27.3076923076923, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=25.5725190839695, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=25.6603773584906, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=264, Percent_Identity=28.4090909090909, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=269, Percent_Identity=27.5092936802974, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=27.5193798449612, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.9701492537313, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=28.996282527881, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=28.7272727272727, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=30.1470588235294, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=276, Percent_Identity=29.7101449275362, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=31.1111111111111, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=24.2307692307692, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=29.3233082706767, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=28.2527881040892, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=27.2373540856031, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=29.7794117647059, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=27.2401433691756, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=29.4776119402985, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=28.6245353159851, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=27.6752767527675, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=27.8985507246377, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=28.4671532846715, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=27.3062730627306, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=167, Percent_Identity=27.5449101796407, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=243, Percent_Identity=26.7489711934156, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=29.8507462686567, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=169, Percent_Identity=26.6272189349112, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=274, Percent_Identity=28.1021897810219, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=217, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=217, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=29.5019157088123, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=29.296875, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=27.734375, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737361, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=26.2548262548263, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641232, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644337, Length=266, Percent_Identity=27.0676691729323, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=25.3846153846154, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 28559; Mature: 28559

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKTRLASKNILITGSARGMGAATAENYAAQGAKVCIADLNIDGCNEVVARIIANGGQAI
CCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEE
AVQMDVTNRESIAAGVQATVDAFGSINVMLNNAGINKPLMFMDITEENWHQIMTVNGLGC
EEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHH
LMGMQEAARQMIKQGPQDEPYKIINVGSILSRQAFDDVVPYSCSKHAVLAMINGGAKALV
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEE
QHNITVNGYGPGVVRTELWEQLDKDLVAIGKFKKEGESMDTLAADSILLGRYSYPEDITG
EECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEECCCCCCCCCC
TASFLASKDSDYMTGQLIMIDGGMIMQ
HHHHHHCCCCCCEEEEEEEEECCEECC
>Mature Secondary Structure
MDKTRLASKNILITGSARGMGAATAENYAAQGAKVCIADLNIDGCNEVVARIIANGGQAI
CCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEE
AVQMDVTNRESIAAGVQATVDAFGSINVMLNNAGINKPLMFMDITEENWHQIMTVNGLGC
EEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHH
LMGMQEAARQMIKQGPQDEPYKIINVGSILSRQAFDDVVPYSCSKHAVLAMINGGAKALV
HHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEE
QHNITVNGYGPGVVRTELWEQLDKDLVAIGKFKKEGESMDTLAADSILLGRYSYPEDITG
EECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEECCCCCCCCCC
TASFLASKDSDYMTGQLIMIDGGMIMQ
HHHHHHCCCCCCEEEEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA