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The map label for this gene is gcvT [H]

Identifier: 119946355

GI number: 119946355

Start: 3344128

End: 3345258

Strand: Reverse

Name: gcvT [H]

Synonym: Ping_2726

Alternate gene names: 119946355

Gene position: 3345258-3344128 (Counterclockwise)

Preceding gene: 119946356

Following gene: 119946346

Centisome position: 73.37

GC content: 46.77

Gene sequence:

>1131_bases
ATGTCCGATTCACTGTCCGAAGAACTTTTGGTTACCCCGCTGCACGCACTGCACATTGAAATGGGGGGTAAAATGGTCCC
TTTTGCGGGTTATGATATGCCCGTGCAATATTCACTGGGAGTGCGTAAGGAACATCTGCATTGCCGTGATGCTGCTGGCT
TATTTGATGTTTCACATATGGGGCAGGTGCGTCTTTTTGGTGAAAATGCAGCGGAGGGATTAGAGGCCTTAGTCCCCGTT
GATATTATGGATTTACCCGTGGGCAAACAACGTTATGCTTTCTTCACTAATGAGCAGGGCGGCATTAATGATGATTTAAT
GGTGGGTAACCTTGGCGATTTTTTATTGGTTGTGGTCAATGCGGCGTGTAAACAACAAGATATTGCGCATCTGCGGGCTA
ATCTTCCCAGTGATGTCAGGTTAGAAGTGATCGAAGATCGTGCTTTACTGGCATTACAAGGTCCGCAAGCGGTAGAGGTT
CTGGCGAAGATTAATCCGGCGGTCAACAATATGCGCTTTATGGATGCTATGAAAATACAGCTGGCGGGTGTCGAATGTTA
TGTTAGCCGCTCCGGTTATACGGGTGAAGACGGCTTTGAAATTTCTGTCCCTGCCGCACAAGCTGAGGCTCTGGCACGTG
AACTGCTGGCTTTTGCTGAAGTTGAGTGGATTGGTCTTGGCGCACGAGACTCATTACGTCTGGAAGCGGGTTTATGTTTA
TATGGCCATGATCTTGATGAAACCACAACACCGGTCGAAGCAAGTTTATTATGGGGTATTAGCAAAGCTCGTCGTGCAGA
GGGTAGTCGTCCAGGTGGTTTTCCGGGTGCTGACATTATTCTTGAACAGATCAAAAGCAAAAATATTACCCGTAAGCGTG
TCGGTTTATTGGGCACATCAAAAGCGCCGGTGCGTGAAGGTTGTGAATTGTTTGATGCGGCTGATAATAAAATTGGTATT
GTTACCAGCGGTACCTTCGGCCCTTCAAAAGGGATGCCTGTTGCAATGGCCTATGTTGATGTGAATTGCAGCCAAATCGG
GTCGGAAGTCTTTGCTGAAGTGCGTGCTAAAAAACTGCCCATGACAGTAGTAAAAATGCCTTTTGTTGAAGCGAATTACT
TTAGAGGTTAA

Upstream 100 bases:

>100_bases
GCTGCACCATAAGTTGAAAAATAACCACCAAAACGATTGTCTCCATCTGACAATTAAATGAACCAGCCGCAACTATTGCG
CAATATGGAGTATTAAACCT

Downstream 100 bases:

>100_bases
AGCTTCCGTGGTTAAAAATTTACGCGGTTAAAAAACAGTCTTTAAAAAAGGAGCGTATTACGCTTCTTTTTTTTATTAGC
CGCTGCCACATTACCCCCCT

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSDSLSEELLVTPLHALHIEMGGKMVPFAGYDMPVQYSLGVRKEHLHCRDAAGLFDVSHMGQVRLFGENAAEGLEALVPV
DIMDLPVGKQRYAFFTNEQGGINDDLMVGNLGDFLLVVVNAACKQQDIAHLRANLPSDVRLEVIEDRALLALQGPQAVEV
LAKINPAVNNMRFMDAMKIQLAGVECYVSRSGYTGEDGFEISVPAAQAEALARELLAFAEVEWIGLGARDSLRLEAGLCL
YGHDLDETTTPVEASLLWGISKARRAEGSRPGGFPGADIILEQIKSKNITRKRVGLLGTSKAPVREGCELFDAADNKIGI
VTSGTFGPSKGMPVAMAYVDVNCSQIGSEVFAEVRAKKLPMTVVKMPFVEANYFRG

Sequences:

>Translated_376_residues
MSDSLSEELLVTPLHALHIEMGGKMVPFAGYDMPVQYSLGVRKEHLHCRDAAGLFDVSHMGQVRLFGENAAEGLEALVPV
DIMDLPVGKQRYAFFTNEQGGINDDLMVGNLGDFLLVVVNAACKQQDIAHLRANLPSDVRLEVIEDRALLALQGPQAVEV
LAKINPAVNNMRFMDAMKIQLAGVECYVSRSGYTGEDGFEISVPAAQAEALARELLAFAEVEWIGLGARDSLRLEAGLCL
YGHDLDETTTPVEASLLWGISKARRAEGSRPGGFPGADIILEQIKSKNITRKRVGLLGTSKAPVREGCELFDAADNKIGI
VTSGTFGPSKGMPVAMAYVDVNCSQIGSEVFAEVRAKKLPMTVVKMPFVEANYFRG
>Mature_375_residues
SDSLSEELLVTPLHALHIEMGGKMVPFAGYDMPVQYSLGVRKEHLHCRDAAGLFDVSHMGQVRLFGENAAEGLEALVPVD
IMDLPVGKQRYAFFTNEQGGINDDLMVGNLGDFLLVVVNAACKQQDIAHLRANLPSDVRLEVIEDRALLALQGPQAVEVL
AKINPAVNNMRFMDAMKIQLAGVECYVSRSGYTGEDGFEISVPAAQAEALARELLAFAEVEWIGLGARDSLRLEAGLCLY
GHDLDETTTPVEASLLWGISKARRAEGSRPGGFPGADIILEQIKSKNITRKRVGLLGTSKAPVREGCELFDAADNKIGIV
TSGTFGPSKGMPVAMAYVDVNCSQIGSEVFAEVRAKKLPMTVVKMPFVEANYFRG

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=377, Percent_Identity=46.9496021220159, Blast_Score=294, Evalue=9e-80,
Organism=Homo sapiens, GI257796258, Length=357, Percent_Identity=46.4985994397759, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI257796254, Length=370, Percent_Identity=42.972972972973, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI257796256, Length=322, Percent_Identity=45.9627329192547, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI24797151, Length=341, Percent_Identity=25.5131964809384, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI197927446, Length=323, Percent_Identity=26.625386996904, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI21361378, Length=323, Percent_Identity=26.625386996904, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI194306651, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789272, Length=375, Percent_Identity=35.2, Blast_Score=184, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI17560118, Length=378, Percent_Identity=42.5925925925926, Blast_Score=284, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6320222, Length=388, Percent_Identity=39.6907216494845, Blast_Score=263, Evalue=3e-71,
Organism=Drosophila melanogaster, GI20129441, Length=379, Percent_Identity=45.3825857519789, Blast_Score=298, Evalue=6e-81,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40682; Mature: 40551

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSLSEELLVTPLHALHIEMGGKMVPFAGYDMPVQYSLGVRKEHLHCRDAAGLFDVSHM
CCCCCCCHHHHCCCEEEEEECCCEECCCCCCCCCEEEECCCCHHHCCHHCCCCCEECCCC
GQVRLFGENAAEGLEALVPVDIMDLPVGKQRYAFFTNEQGGINDDLMVGNLGDFLLVVVN
CEEEEECCCHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHH
AACKQQDIAHLRANLPSDVRLEVIEDRALLALQGPQAVEVLAKINPAVNNMRFMDAMKIQ
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHHHHHCCHHHCCEEHHEEEEEE
LAGVECYVSRSGYTGEDGFEISVPAAQAEALARELLAFAEVEWIGLGARDSLRLEAGLCL
EEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCEEE
YGHDLDETTTPVEASLLWGISKARRAEGSRPGGFPGADIILEQIKSKNITRKRVGLLGTS
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KAPVREGCELFDAADNKIGIVTSGTFGPSKGMPVAMAYVDVNCSQIGSEVFAEVRAKKLP
CCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC
MTVVKMPFVEANYFRG
EEEEECCCCCCCCCCC
>Mature Secondary Structure 
SDSLSEELLVTPLHALHIEMGGKMVPFAGYDMPVQYSLGVRKEHLHCRDAAGLFDVSHM
CCCCCCHHHHCCCEEEEEECCCEECCCCCCCCCEEEECCCCHHHCCHHCCCCCEECCCC
GQVRLFGENAAEGLEALVPVDIMDLPVGKQRYAFFTNEQGGINDDLMVGNLGDFLLVVVN
CEEEEECCCHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHH
AACKQQDIAHLRANLPSDVRLEVIEDRALLALQGPQAVEVLAKINPAVNNMRFMDAMKIQ
HHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHHHHHCCHHHCCEEHHEEEEEE
LAGVECYVSRSGYTGEDGFEISVPAAQAEALARELLAFAEVEWIGLGARDSLRLEAGLCL
EEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCEEE
YGHDLDETTTPVEASLLWGISKARRAEGSRPGGFPGADIILEQIKSKNITRKRVGLLGTS
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHCCCCCC
KAPVREGCELFDAADNKIGIVTSGTFGPSKGMPVAMAYVDVNCSQIGSEVFAEVRAKKLP
CCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCC
MTVVKMPFVEANYFRG
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA