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The map label for this gene is ctaC [H]

Identifier: 119946346

GI number: 119946346

Start: 3332397

End: 3333968

Strand: Reverse

Name: ctaC [H]

Synonym: Ping_2717

Alternate gene names: 119946346

Gene position: 3333968-3332397 (Counterclockwise)

Preceding gene: 119946355

Following gene: 119946345

Centisome position: 73.12

GC content: 43.32

Gene sequence:

>1572_bases
ATGATTGTTACACGAGTTGCTTTTTTATCCACTTTGCTTATTCCTCAATTAAGTTTTGCAAACAGCGCTTTTAATATGCG
GGGGGGTGTTACTGATATCAGTGAAGATGTCTATCAATTGCATATGACTATTTTTCTTATCTGTTGTGCGATTGCCGTCG
TCGTCTTTGGTATTATGTTCTGGTCTATTTTTCATCATCGTAAATCCAAAGGTTTTAAACCCGCCCAATTCCATGAAAGT
ACTAAAATTGAAGTGTTATGGACAGCTATTCCATTTGTTATCCTGATAGCCATGGCAGTCCCTGCCACCAAGACCCTGAT
TGCGATGGAGGATAACAGTAAAGCAGATATTACTATTAAGGTAACAGGCTCACAATGGAAGTGGCATTATCAATACCTTA
GTTATAATAATGAAATCCTCGATATAGATTTTTATTCGGTTACTTCTACCCCGCAGGCACAAATAAACAATCAGGAAGAA
AAAACATCCACCTATCTCCTTGAAGTTGATAACCCTTTGGTTGTCCCAATCAATAAAAAAGTACGTTTTGTAATAACCTC
CGACGATGTTATTCACTCCTGGTGGGTCCCCGATTTTGCAATAAAACAAGATGCGGTTCCTGGCTTTATTAATGAAGCTT
GGGCACGTGTTAACGAGGTTGGTATCTATCGTGGTCAATGTGCCGAGTTATGCGGCAAAAACCACGGTTTTATGCCGATC
GTTGTTGATGCGATGGCAGAAAATGATTTTGATAACTGGTTGGCCCAGGCAAAAATAGCGAAACAAAAAGAAGCGCAGGA
AGCCCTGGCGTCACAGTCTACCAGCTTCTCTAAAACGGATCTTATGACCCAGGGTGAACAAGTCTATGTGGGGCATTGTT
CTGTTTGCCATCAGCCAACGGGGACCGGATTGCCGGGGGTTTTCCCCGCATTAAAAGGCAGTGCGATAGCAACGGGTGAT
TTAAATGCGCATATTAATATTGTCTTAAATGGCAAGTCAGGCACGGCGATGCAGTCTTTTTCAAAGCAGTTATCACTTAA
AGAATTAGCCGCTGTTATCACCTATGAACGTAATGCCTGGGACAATAATACGGGAGATTTGGTGCAGCCGATTCAAATTA
GTAATGCCATGAATCCACAGGAAAGCGATGCAGCGCAGGCAGCAATAAAAAACGTTGAAGCCAAGGAGGCTATTGATGAA
GCTGTTCCGGTTGCAGCAGATAAAACCATGCAGGAGCTACCCTTGTCCAAGTTAACAAAAGAGCAGCTTATGACCTCCGG
TGAACAGGATTATTTGACTTTCTGTGCTGCTTGCCATCAACCAACTGGTCTGGGTATTCCAGGTGCCTTTCCGGCATTAA
AAGGTAGCCCACTGGTCAAAGGGGCTGTCTCTGAACACCTAAATATTGTATTAAAAGGAAAAGCAGGCACCGCAATGCAA
CCTTTCGCAGAACAACTAAGCGCTGAACAGTTAGCGGCTATTATCACCTATGAGCGTAATGCCTGGGGTAATGATACGGG
TGACCTGGTGCAACCCAACGATATTGAGCAGGCAATTAAGGGAGAACGGTAA

Upstream 100 bases:

>100_bases
TCGGCTGAATATTTAGCTGTTTTTATAGTACTTTTTATCTAAATGTGTACCAGAGATTACTATCATTTATCATTACGTTC
CGCCTAAAAGGAAATGTTGC

Downstream 100 bases:

>100_bases
TGACAGGTGCAGCCGATAACACTCAAGACTCTTATCCTCAAACTACCGAGCATAATGAACATCACGCGCCGACAGGCTTT
AAACGCTGGTTCTTTAGTAC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MIVTRVAFLSTLLIPQLSFANSAFNMRGGVTDISEDVYQLHMTIFLICCAIAVVVFGIMFWSIFHHRKSKGFKPAQFHES
TKIEVLWTAIPFVILIAMAVPATKTLIAMEDNSKADITIKVTGSQWKWHYQYLSYNNEILDIDFYSVTSTPQAQINNQEE
KTSTYLLEVDNPLVVPINKKVRFVITSDDVIHSWWVPDFAIKQDAVPGFINEAWARVNEVGIYRGQCAELCGKNHGFMPI
VVDAMAENDFDNWLAQAKIAKQKEAQEALASQSTSFSKTDLMTQGEQVYVGHCSVCHQPTGTGLPGVFPALKGSAIATGD
LNAHINIVLNGKSGTAMQSFSKQLSLKELAAVITYERNAWDNNTGDLVQPIQISNAMNPQESDAAQAAIKNVEAKEAIDE
AVPVAADKTMQELPLSKLTKEQLMTSGEQDYLTFCAACHQPTGLGIPGAFPALKGSPLVKGAVSEHLNIVLKGKAGTAMQ
PFAEQLSAEQLAAIITYERNAWGNDTGDLVQPNDIEQAIKGER

Sequences:

>Translated_523_residues
MIVTRVAFLSTLLIPQLSFANSAFNMRGGVTDISEDVYQLHMTIFLICCAIAVVVFGIMFWSIFHHRKSKGFKPAQFHES
TKIEVLWTAIPFVILIAMAVPATKTLIAMEDNSKADITIKVTGSQWKWHYQYLSYNNEILDIDFYSVTSTPQAQINNQEE
KTSTYLLEVDNPLVVPINKKVRFVITSDDVIHSWWVPDFAIKQDAVPGFINEAWARVNEVGIYRGQCAELCGKNHGFMPI
VVDAMAENDFDNWLAQAKIAKQKEAQEALASQSTSFSKTDLMTQGEQVYVGHCSVCHQPTGTGLPGVFPALKGSAIATGD
LNAHINIVLNGKSGTAMQSFSKQLSLKELAAVITYERNAWDNNTGDLVQPIQISNAMNPQESDAAQAAIKNVEAKEAIDE
AVPVAADKTMQELPLSKLTKEQLMTSGEQDYLTFCAACHQPTGLGIPGAFPALKGSPLVKGAVSEHLNIVLKGKAGTAMQ
PFAEQLSAEQLAAIITYERNAWGNDTGDLVQPNDIEQAIKGER
>Mature_523_residues
MIVTRVAFLSTLLIPQLSFANSAFNMRGGVTDISEDVYQLHMTIFLICCAIAVVVFGIMFWSIFHHRKSKGFKPAQFHES
TKIEVLWTAIPFVILIAMAVPATKTLIAMEDNSKADITIKVTGSQWKWHYQYLSYNNEILDIDFYSVTSTPQAQINNQEE
KTSTYLLEVDNPLVVPINKKVRFVITSDDVIHSWWVPDFAIKQDAVPGFINEAWARVNEVGIYRGQCAELCGKNHGFMPI
VVDAMAENDFDNWLAQAKIAKQKEAQEALASQSTSFSKTDLMTQGEQVYVGHCSVCHQPTGTGLPGVFPALKGSAIATGD
LNAHINIVLNGKSGTAMQSFSKQLSLKELAAVITYERNAWDNNTGDLVQPIQISNAMNPQESDAAQAAIKNVEAKEAIDE
AVPVAADKTMQELPLSKLTKEQLMTSGEQDYLTFCAACHQPTGLGIPGAFPALKGSPLVKGAVSEHLNIVLKGKAGTAMQ
PFAEQLSAEQLAAIITYERNAWGNDTGDLVQPNDIEQAIKGER

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=173, Percent_Identity=37.5722543352601, Blast_Score=134, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6226540, Length=228, Percent_Identity=31.140350877193, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 57314; Mature: 57314

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTRVAFLSTLLIPQLSFANSAFNMRGGVTDISEDVYQLHMTIFLICCAIAVVVFGIMF
CEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSIFHHRKSKGFKPAQFHESTKIEVLWTAIPFVILIAMAVPATKTLIAMEDNSKADITIK
HHHHHHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
VTGSQWKWHYQYLSYNNEILDIDFYSVTSTPQAQINNQEEKTSTYLLEVDNPLVVPINKK
EECCCEEEEEEEECCCCEEEEEEEEEECCCCHHHCCCCCCCCEEEEEEECCCEEEEECCC
VRFVITSDDVIHSWWVPDFAIKQDAVPGFINEAWARVNEVGIYRGQCAELCGKNHGFMPI
EEEEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEE
VVDAMAENDFDNWLAQAKIAKQKEAQEALASQSTSFSKTDLMTQGEQVYVGHCSVCHQPT
EEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEHCCCCCC
GTGLPGVFPALKGSAIATGDLNAHINIVLNGKSGTAMQSFSKQLSLKELAAVITYERNAW
CCCCCCHHHHHCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCCC
DNNTGDLVQPIQISNAMNPQESDAAQAAIKNVEAKEAIDEAVPVAADKTMQELPLSKLTK
CCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCHHHHHH
EQLMTSGEQDYLTFCAACHQPTGLGIPGAFPALKGSPLVKGAVSEHLNIVLKGKAGTAMQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCHH
PFAEQLSAEQLAAIITYERNAWGNDTGDLVQPNDIEQAIKGER
HHHHHHCHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MIVTRVAFLSTLLIPQLSFANSAFNMRGGVTDISEDVYQLHMTIFLICCAIAVVVFGIMF
CEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSIFHHRKSKGFKPAQFHESTKIEVLWTAIPFVILIAMAVPATKTLIAMEDNSKADITIK
HHHHHHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEE
VTGSQWKWHYQYLSYNNEILDIDFYSVTSTPQAQINNQEEKTSTYLLEVDNPLVVPINKK
EECCCEEEEEEEECCCCEEEEEEEEEECCCCHHHCCCCCCCCEEEEEEECCCEEEEECCC
VRFVITSDDVIHSWWVPDFAIKQDAVPGFINEAWARVNEVGIYRGQCAELCGKNHGFMPI
EEEEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEE
VVDAMAENDFDNWLAQAKIAKQKEAQEALASQSTSFSKTDLMTQGEQVYVGHCSVCHQPT
EEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEEEHCCCCCC
GTGLPGVFPALKGSAIATGDLNAHINIVLNGKSGTAMQSFSKQLSLKELAAVITYERNAW
CCCCCCHHHHHCCCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCCC
DNNTGDLVQPIQISNAMNPQESDAAQAAIKNVEAKEAIDEAVPVAADKTMQELPLSKLTK
CCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCHHHHHH
EQLMTSGEQDYLTFCAACHQPTGLGIPGAFPALKGSPLVKGAVSEHLNIVLKGKAGTAMQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCHH
PFAEQLSAEQLAAIITYERNAWGNDTGDLVQPNDIEQAIKGER
HHHHHHCHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA