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The map label for this gene is cyoB [H]

Identifier: 119946345

GI number: 119946345

Start: 3330793

End: 3332397

Strand: Reverse

Name: cyoB [H]

Synonym: Ping_2716

Alternate gene names: 119946345

Gene position: 3332397-3330793 (Counterclockwise)

Preceding gene: 119946346

Following gene: 119946344

Centisome position: 73.09

GC content: 43.93

Gene sequence:

>1605_bases
ATGACAGGTGCAGCCGATAACACTCAAGACTCTTATCCTCAAACTACCGAGCATAATGAACATCACGCGCCGACAGGCTT
TAAACGCTGGTTCTTTAGTACCAACCATAAAGATATTGGTACGCTCTATTTAGGTTTTTCATTACTTATGTTCTTAATTG
GTGGTGCCATGGCGATGCTGATTAGGGCTGAATTATTTCAACCCGGTCTGCAGCTTATGGAGCCCCATTTTTATAACCAA
ATGGTCACGGTTCATGGTTTGATTATGGTCTTTGGTGCAGTTATGCCAGCTTTTGTCGGTCTGGCCAATTGGATGATTCC
GTTGATGATCGGTGCGCCTGATATGGCGTTACCGCGCATGAATAACTGGAGCTTTTGGATTTTGCCCTTTGCTTTTGCCA
TGTTGTTAGGGTCGTTATTTATGGAAGGCGGTGGTCCAGCCTTTGGATGGACTTTTTATGCTCCATTATCAACAACTTAT
AGCAATGACAATACGGCCATGTTTGTTTTTGCCGTACATATAATGGGGATTAGTTCAATAATGGGGGCGATTAACGTTAT
TGTCACAATTGTGAATTTACGCGCCCCCGGTATGACCTGGATGAAGACGCCAATGTTCGTTTGGACATGGCTTATTACTG
CTTTTTTATTAATTGCGGTGATGCCCGTATTGGCCGGTGCCGTGACTATGGTATTAACCGATAAATACTTTGGCACTGAC
TTCTTTAATGCCATGGGCGGTGGGGATCCGGTGATGTTCCAGCATATATTCTGGTTCTTTGGTCACCCTGAAGTTTATAT
TATGATCTTGCCCGCATTCGGTATTATTTCTACCATAGTACCGACCTTCTCACGTAAAAAGCTCTTTGGTTACCATTCGA
TGGTCTATGCCACGGGTTCAATCGCAATATTATCTTTTGTGGTCTGGATGCATCATATGTTTACTACCGGTATGCCGTTA
GCTGCCGAATTATTTTTTATGTATAGCACTATGCTTATCTCGGTGCCCACCGGGGTGAAAATCTTTAACTGGGTGGCTAC
TATGTGGCGAGGTGCGATCTCCTTTGAAGTGCCGATGTTATTTGCGATTGCCTTTATTGTTTTGTTTACCATAGGCGGAT
TTTCCGGCCTGATGTTAGCCATTACCCCAGCCGATTTCCAGTACCATGATACCTACTTTGTAGTGGCACATTTTCATTAT
GTCTTAGTGACCGGTGCCGTCTTTTCAATTATGGCAGGCGTTTATTACTGGCTGCCGAAATGGTCCGGCCACATGTTTGA
TATCAGGCTTGCAAAAACACATTTTTGGTTATCATTAATCAGCGTAAATATCCTTTTTTTCCCGATGCATTTTGTTGGAT
TAGCGGGGATGCCCCGTCGTATTCCTGATTATGCGCTGCAGTTTGCTGATTTCAACGCCATTATCAGTATCGGTGGTTTT
GCCTTTGGTTTATCCCAATTATTATTTGTCTGGGTGGTTTTAAAATGTGTTAGAGGGGGAGAAAAAGTACCGGCAAACGT
CTGGCAAGCCGCAGAAGGTTTAGAATGGGATGTGCCTTCTCCCGCGCCGCATCATACCTTTGTCACTCCACCCGTGATTA
AATAA

Upstream 100 bases:

>100_bases
TAGCGGCTATTATCACCTATGAGCGTAATGCCTGGGGTAATGATACGGGTGACCTGGTGCAACCCAACGATATTGAGCAG
GCAATTAAGGGAGAACGGTA

Downstream 100 bases:

>100_bases
TGCTTAGTCAATGAGTAAACATACTAAGTTATTTAAGAAATTGGTTTTAGCAAGCGTAGGCATGTTCGCTTTTGCCTTTG
CGTTAGTCCCGCTATATGAC

Product: cytochrome c oxidase, subunit I CyoB

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTGAADNTQDSYPQTTEHNEHHAPTGFKRWFFSTNHKDIGTLYLGFSLLMFLIGGAMAMLIRAELFQPGLQLMEPHFYNQ
MVTVHGLIMVFGAVMPAFVGLANWMIPLMIGAPDMALPRMNNWSFWILPFAFAMLLGSLFMEGGGPAFGWTFYAPLSTTY
SNDNTAMFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKTPMFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTD
FFNAMGGGDPVMFQHIFWFFGHPEVYIMILPAFGIISTIVPTFSRKKLFGYHSMVYATGSIAILSFVVWMHHMFTTGMPL
AAELFFMYSTMLISVPTGVKIFNWVATMWRGAISFEVPMLFAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHY
VLVTGAVFSIMAGVYYWLPKWSGHMFDIRLAKTHFWLSLISVNILFFPMHFVGLAGMPRRIPDYALQFADFNAIISIGGF
AFGLSQLLFVWVVLKCVRGGEKVPANVWQAAEGLEWDVPSPAPHHTFVTPPVIK

Sequences:

>Translated_534_residues
MTGAADNTQDSYPQTTEHNEHHAPTGFKRWFFSTNHKDIGTLYLGFSLLMFLIGGAMAMLIRAELFQPGLQLMEPHFYNQ
MVTVHGLIMVFGAVMPAFVGLANWMIPLMIGAPDMALPRMNNWSFWILPFAFAMLLGSLFMEGGGPAFGWTFYAPLSTTY
SNDNTAMFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKTPMFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTD
FFNAMGGGDPVMFQHIFWFFGHPEVYIMILPAFGIISTIVPTFSRKKLFGYHSMVYATGSIAILSFVVWMHHMFTTGMPL
AAELFFMYSTMLISVPTGVKIFNWVATMWRGAISFEVPMLFAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHY
VLVTGAVFSIMAGVYYWLPKWSGHMFDIRLAKTHFWLSLISVNILFFPMHFVGLAGMPRRIPDYALQFADFNAIISIGGF
AFGLSQLLFVWVVLKCVRGGEKVPANVWQAAEGLEWDVPSPAPHHTFVTPPVIK
>Mature_533_residues
TGAADNTQDSYPQTTEHNEHHAPTGFKRWFFSTNHKDIGTLYLGFSLLMFLIGGAMAMLIRAELFQPGLQLMEPHFYNQM
VTVHGLIMVFGAVMPAFVGLANWMIPLMIGAPDMALPRMNNWSFWILPFAFAMLLGSLFMEGGGPAFGWTFYAPLSTTYS
NDNTAMFVFAVHIMGISSIMGAINVIVTIVNLRAPGMTWMKTPMFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTDF
FNAMGGGDPVMFQHIFWFFGHPEVYIMILPAFGIISTIVPTFSRKKLFGYHSMVYATGSIAILSFVVWMHHMFTTGMPLA
AELFFMYSTMLISVPTGVKIFNWVATMWRGAISFEVPMLFAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYV
LVTGAVFSIMAGVYYWLPKWSGHMFDIRLAKTHFWLSLISVNILFFPMHFVGLAGMPRRIPDYALQFADFNAIISIGGFA
FGLSQLLFVWVVLKCVRGGEKVPANVWQAAEGLEWDVPSPAPHHTFVTPPVIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=49.5107632093933, Blast_Score=459, Evalue=1e-129,
Organism=Escherichia coli, GI1786634, Length=513, Percent_Identity=39.5711500974659, Blast_Score=350, Evalue=9e-98,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=45.9510357815443, Blast_Score=461, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=47.9876160990712, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=44.5344129554656, Blast_Score=198, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59796; Mature: 59664

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAADNTQDSYPQTTEHNEHHAPTGFKRWFFSTNHKDIGTLYLGFSLLMFLIGGAMAML
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IRAELFQPGLQLMEPHFYNQMVTVHGLIMVFGAVMPAFVGLANWMIPLMIGAPDMALPRM
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNWSFWILPFAFAMLLGSLFMEGGGPAFGWTFYAPLSTTYSNDNTAMFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCCEEHHHHHHHHHHHHH
MGAINVIVTIVNLRAPGMTWMKTPMFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCH
FFNAMGGGDPVMFQHIFWFFGHPEVYIMILPAFGIISTIVPTFSRKKLFGYHSMVYATGS
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
IAILSFVVWMHHMFTTGMPLAAELFFMYSTMLISVPTGVKIFNWVATMWRGAISFEVPML
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHEHHHHH
FAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAVFSIMAGVYYWLPK
HHHHHHHHHHHCCCCCEEEEEECCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
WSGHMFDIRLAKTHFWLSLISVNILFFPMHFVGLAGMPRRIPDYALQFADFNAIISIGGF
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHH
AFGLSQLLFVWVVLKCVRGGEKVPANVWQAAEGLEWDVPSPAPHHTFVTPPVIK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGAADNTQDSYPQTTEHNEHHAPTGFKRWFFSTNHKDIGTLYLGFSLLMFLIGGAMAML
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IRAELFQPGLQLMEPHFYNQMVTVHGLIMVFGAVMPAFVGLANWMIPLMIGAPDMALPRM
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNWSFWILPFAFAMLLGSLFMEGGGPAFGWTFYAPLSTTYSNDNTAMFVFAVHIMGISSI
CCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCCCCEEHHHHHHHHHHHHH
MGAINVIVTIVNLRAPGMTWMKTPMFVWTWLITAFLLIAVMPVLAGAVTMVLTDKYFGTD
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCH
FFNAMGGGDPVMFQHIFWFFGHPEVYIMILPAFGIISTIVPTFSRKKLFGYHSMVYATGS
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCCHH
IAILSFVVWMHHMFTTGMPLAAELFFMYSTMLISVPTGVKIFNWVATMWRGAISFEVPML
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHEHHHHH
FAIAFIVLFTIGGFSGLMLAITPADFQYHDTYFVVAHFHYVLVTGAVFSIMAGVYYWLPK
HHHHHHHHHHHCCCCCEEEEEECCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
WSGHMFDIRLAKTHFWLSLISVNILFFPMHFVGLAGMPRRIPDYALQFADFNAIISIGGF
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHH
AFGLSQLLFVWVVLKCVRGGEKVPANVWQAAEGLEWDVPSPAPHHTFVTPPVIK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]