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The map label for this gene is tcyB [H]

Identifier: 119946082

GI number: 119946082

Start: 2979115

End: 2979783

Strand: Reverse

Name: tcyB [H]

Synonym: Ping_2431

Alternate gene names: 119946082

Gene position: 2979783-2979115 (Counterclockwise)

Preceding gene: 119946083

Following gene: 119946081

Centisome position: 65.35

GC content: 40.81

Gene sequence:

>669_bases
ATGAGCTATAATCTTGATTTTTATGGGTTGGTTCCTTATCTGCCACAGTTTGTGGCAGGTGTAGGTACAACAATACAACT
AACGGTTATTTCTACCGTTTTAGGGTTAATACTCGGAACATATTGTGCGGCAGGGCGTATTAGTAAAGCGCGTTGGTTAA
ATTGGATTTGCGCTGTTTATATCGAAGTGACGCGAAATACGCCCTTTATTATTCAATTGTTTTTTATCTTTTTTGGGCTG
CCCGCATTAGGGATTAAGCTTTCTGCATGGCAGGCAGGAATGATTGCGATGGTGTTTAACTTAGGTGCTTACAGTGCCGA
AATTATTCGCGCAGGTATTGAGGCAACGGCAATAGGCCAATGGGAAGCGGCAAAAACCTTAGGTCTTACACACCGCCAAA
TTTTTATGCATGTTATTTTGCCACCCGCCTATCAACGGGTTTATCCGGCACTGGTCAGTCAATGTATTATTGTGATGTTA
GGCTCCGCCGTGGTGTCACAAATATCAGTCGAAGAACTTACTTTTGCGGCAAACTTTGTTCAATCGCGCAGTTTTTTGAG
TTTTGAATCTTATATGTTAACAGCGCTGATTTACCTTTTTTTAGCGATTTTAATGCGTCAACTATTCTCACTGCTGAAAA
AATTCATCTTTAAATCATCTGCTGTATAG

Upstream 100 bases:

>100_bases
AACAAGTTGGTGTACTTGAAGGATTTTCACAGAAATGGTTAAAAGCCCCATTTCCTGCAGACCTCAGCGCATAACTTACT
GACAATATAAGCACTTTTCT

Downstream 100 bases:

>100_bases
GAAACAAAATAATGATGCAATTTACAGACTGGGATATTTTAAGAAATTTATTGTTTGCAGCGCGTTGGACATTGCTGCTT
TCTCTCTTTGCTTTTATTGG

Product: ABC polar amino acid transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSYNLDFYGLVPYLPQFVAGVGTTIQLTVISTVLGLILGTYCAAGRISKARWLNWICAVYIEVTRNTPFIIQLFFIFFGL
PALGIKLSAWQAGMIAMVFNLGAYSAEIIRAGIEATAIGQWEAAKTLGLTHRQIFMHVILPPAYQRVYPALVSQCIIVML
GSAVVSQISVEELTFAANFVQSRSFLSFESYMLTALIYLFLAILMRQLFSLLKKFIFKSSAV

Sequences:

>Translated_222_residues
MSYNLDFYGLVPYLPQFVAGVGTTIQLTVISTVLGLILGTYCAAGRISKARWLNWICAVYIEVTRNTPFIIQLFFIFFGL
PALGIKLSAWQAGMIAMVFNLGAYSAEIIRAGIEATAIGQWEAAKTLGLTHRQIFMHVILPPAYQRVYPALVSQCIIVML
GSAVVSQISVEELTFAANFVQSRSFLSFESYMLTALIYLFLAILMRQLFSLLKKFIFKSSAV
>Mature_221_residues
SYNLDFYGLVPYLPQFVAGVGTTIQLTVISTVLGLILGTYCAAGRISKARWLNWICAVYIEVTRNTPFIIQLFFIFFGLP
ALGIKLSAWQAGMIAMVFNLGAYSAEIIRAGIEATAIGQWEAAKTLGLTHRQIFMHVILPPAYQRVYPALVSQCIIVMLG
SAVVSQISVEELTFAANFVQSRSFLSFESYMLTALIYLFLAILMRQLFSLLKKFIFKSSAV

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=195, Percent_Identity=36.4102564102564, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1786873, Length=223, Percent_Identity=28.6995515695067, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787030, Length=211, Percent_Identity=28.9099526066351, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787087, Length=210, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788645, Length=205, Percent_Identity=24.8780487804878, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787086, Length=183, Percent_Identity=26.775956284153, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1786874, Length=220, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788646, Length=187, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=28.1553398058252, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24664; Mature: 24533

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYNLDFYGLVPYLPQFVAGVGTTIQLTVISTVLGLILGTYCAAGRISKARWLNWICAVY
CCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IEVTRNTPFIIQLFFIFFGLPALGIKLSAWQAGMIAMVFNLGAYSAEIIRAGIEATAIGQ
HHHCCCCCHHHHHHHHHHCCHHHCEEHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHCCCC
WEAAKTLGLTHRQIFMHVILPPAYQRVYPALVSQCIIVMLGSAVVSQISVEELTFAANFV
HHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRSFLSFESYMLTALIYLFLAILMRQLFSLLKKFIFKSSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYNLDFYGLVPYLPQFVAGVGTTIQLTVISTVLGLILGTYCAAGRISKARWLNWICAVY
CCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IEVTRNTPFIIQLFFIFFGLPALGIKLSAWQAGMIAMVFNLGAYSAEIIRAGIEATAIGQ
HHHCCCCCHHHHHHHHHHCCHHHCEEHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHCCCC
WEAAKTLGLTHRQIFMHVILPPAYQRVYPALVSQCIIVMLGSAVVSQISVEELTFAANFV
HHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSRSFLSFESYMLTALIYLFLAILMRQLFSLLKKFIFKSSAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]