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The map label for this gene is rtn [H]

Identifier: 119946062

GI number: 119946062

Start: 2953159

End: 2955057

Strand: Reverse

Name: rtn [H]

Synonym: Ping_2411

Alternate gene names: 119946062

Gene position: 2955057-2953159 (Counterclockwise)

Preceding gene: 119946064

Following gene: 119946060

Centisome position: 64.81

GC content: 38.28

Gene sequence:

>1899_bases
ATGAAAGCAATTTTTATCTGCATTAGAATGGGGATAATTAAGCCGCAGAACTATTCTGTATCAATTTCTCTTACCACTAG
CTGCGATGAAGAAAATATGCCAAATTTAACTATATTATCACTTGATTTGATAATCCAAGATAAAAATCTCAGTGTTTTTT
TTCAGCCTATTGTTGAAAATATTGAACGGAATATTTTTGGCTATGAAGCATTAATTCGGGGCCCCTTTAACAGTCAATTG
TACTCACCCATTGCCCTTTTTGCTGCAGCAAAAGACCAAAGTAGATTAGTGGAGCTGGAGCTTTTATGCCGAGAATTATC
GATATTACAATTTAAAAAACTTAATCTCCAGGGAAAATTATTTCTCAATGCCAGCCCTGAAACTCTCTTTCAGCCTAATT
TCCGCTCTGGTCAAACATTAAAATTACTCAAGAAAATAGACCTTGATCCGAGCCGTGTGGTGATCGAGTTAACCGAACAC
AGTCCTTTAGAAAATTATGAAGTAATTCGAGATGCATTAAAACATTATAAAGAAATGGGCTTTGAAATTGCGATGGATGA
TTTGGGATCCGGTTATTCGGGCTTGCGCGCTTGGTATGAATTACGTCCTGATTATGTAAAGATCGATCGCCATTTTATGT
GTGATATTGACAGCGATAAAGTAAAGCAGCAATTTGTACTCTCTATCAAAAATATCGCGCAGGAGCTGGGTTGTAAAGTC
ATTGCAGAAGGTGTTGAAACAGCCAATGAATTTCGATTTATAGAAAAAATTGGTCTGCGGTTCTGCCAGGGTTACTATTT
TAAGCGTCCGGCACCGTTGCCCGTCAGGCGTATCAATAATAACTTGTTTAGTGAAAGAAGGTTGACAGCGCAATCTAAAA
ATAGACTTATTTCATCTAAAATGGTGGGAGAGTTATTGCAGCCTATTGATGCAATTAGTACAGCAACGACCATTGAATCT
TGCGCTACATTATTTAAGCAAAAACCTGATCTAGACAGTATTCCAGTGCTCGAGAACAACAAACCAATCGGTTTAATCCA
CCGTAACAACCTCACTAATTTATTTTTTTCAGCCTATGGCAGAGAACTCTCAGGCAGAAAGACGATCGCCTCATTGGTTG
ATCGCCAGGTACTGATTTTGGAACATGACTTACCCGTTGAGCAAGCGAGTATCTTAATTAGTGATCAAGCTGGAAGAAGG
AAAATACTGGAGTTTATTATTGTCAATAAGGGGGAATATCAGGGCATTGGCTCAATTATTGATCTTCTCAAGGAAATAAC
CCATCTGCAAATTAATAACGCACGTTATGCAAACCCTTTGACCTTGTTGCCGGGTAACGTGCCGATCAGTAAAAATTTGG
ATCAGCGACTTAAAGAACAATCACCCTTCACTATCTGTTATGTCGATTTAGATCATTTCAAACCGTACAATGATTGTTAT
GGTTATGAAAAAGGAGACCAAATTATTCTTGGTGTTGCTGATATTTTGCGGGATATAGTGACCGATAGAGATGATTTTAT
TGGCCATATTGGTGGGGATGACTTTATTGTTATTTTATCTTCAGATCATTGGCAAATACAATGCGAAAAAATACTGGCAA
ATTTTTCGGAATGGGTTATCCACAGCTATAGTCCGGAAGACCAGGAGAGGGGCGGAATCGCAAGCGAAGATCGTACGGGA
GCCAAACAATTTTATCCTTTACTGAGTCTATCGATAGGTTGTGTCAATTTGTCGCCTTCCATTTGTAACAGTCATAACGA
TGTGGCGGTATTAGCCTCCTATGCAAAATCGAAGGCTAAAAAAATAAAAGGCAATTCATTATATTTATATGACAGTAAAA
CGACGGCCAACGCATTGCCAGAAAAAAAATATCTCACCGAGTTATGTCATAGTTCATGA

Upstream 100 bases:

>100_bases
GTCATAACTAATCGTTACGCTGTATTTCATTATCAGAATCCCATTTTGCTGATTTTTTTTCTTAATTATTAAAATTGCAA
TGTGTTATAAAAAACATGAA

Downstream 100 bases:

>100_bases
TTTTTTATCTTTTCAATTCAAAATTAAAGACAGTCATGGTTGATGCTTAACCGCCGCCGATAATGGTTATTAATTTTTTT
ATAAAAAGTGTTACTGCTTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MKAIFICIRMGIIKPQNYSVSISLTTSCDEENMPNLTILSLDLIIQDKNLSVFFQPIVENIERNIFGYEALIRGPFNSQL
YSPIALFAAAKDQSRLVELELLCRELSILQFKKLNLQGKLFLNASPETLFQPNFRSGQTLKLLKKIDLDPSRVVIELTEH
SPLENYEVIRDALKHYKEMGFEIAMDDLGSGYSGLRAWYELRPDYVKIDRHFMCDIDSDKVKQQFVLSIKNIAQELGCKV
IAEGVETANEFRFIEKIGLRFCQGYYFKRPAPLPVRRINNNLFSERRLTAQSKNRLISSKMVGELLQPIDAISTATTIES
CATLFKQKPDLDSIPVLENNKPIGLIHRNNLTNLFFSAYGRELSGRKTIASLVDRQVLILEHDLPVEQASILISDQAGRR
KILEFIIVNKGEYQGIGSIIDLLKEITHLQINNARYANPLTLLPGNVPISKNLDQRLKEQSPFTICYVDLDHFKPYNDCY
GYEKGDQIILGVADILRDIVTDRDDFIGHIGGDDFIVILSSDHWQIQCEKILANFSEWVIHSYSPEDQERGGIASEDRTG
AKQFYPLLSLSIGCVNLSPSICNSHNDVAVLASYAKSKAKKIKGNSLYLYDSKTTANALPEKKYLTELCHSS

Sequences:

>Translated_632_residues
MKAIFICIRMGIIKPQNYSVSISLTTSCDEENMPNLTILSLDLIIQDKNLSVFFQPIVENIERNIFGYEALIRGPFNSQL
YSPIALFAAAKDQSRLVELELLCRELSILQFKKLNLQGKLFLNASPETLFQPNFRSGQTLKLLKKIDLDPSRVVIELTEH
SPLENYEVIRDALKHYKEMGFEIAMDDLGSGYSGLRAWYELRPDYVKIDRHFMCDIDSDKVKQQFVLSIKNIAQELGCKV
IAEGVETANEFRFIEKIGLRFCQGYYFKRPAPLPVRRINNNLFSERRLTAQSKNRLISSKMVGELLQPIDAISTATTIES
CATLFKQKPDLDSIPVLENNKPIGLIHRNNLTNLFFSAYGRELSGRKTIASLVDRQVLILEHDLPVEQASILISDQAGRR
KILEFIIVNKGEYQGIGSIIDLLKEITHLQINNARYANPLTLLPGNVPISKNLDQRLKEQSPFTICYVDLDHFKPYNDCY
GYEKGDQIILGVADILRDIVTDRDDFIGHIGGDDFIVILSSDHWQIQCEKILANFSEWVIHSYSPEDQERGGIASEDRTG
AKQFYPLLSLSIGCVNLSPSICNSHNDVAVLASYAKSKAKKIKGNSLYLYDSKTTANALPEKKYLTELCHSS
>Mature_632_residues
MKAIFICIRMGIIKPQNYSVSISLTTSCDEENMPNLTILSLDLIIQDKNLSVFFQPIVENIERNIFGYEALIRGPFNSQL
YSPIALFAAAKDQSRLVELELLCRELSILQFKKLNLQGKLFLNASPETLFQPNFRSGQTLKLLKKIDLDPSRVVIELTEH
SPLENYEVIRDALKHYKEMGFEIAMDDLGSGYSGLRAWYELRPDYVKIDRHFMCDIDSDKVKQQFVLSIKNIAQELGCKV
IAEGVETANEFRFIEKIGLRFCQGYYFKRPAPLPVRRINNNLFSERRLTAQSKNRLISSKMVGELLQPIDAISTATTIES
CATLFKQKPDLDSIPVLENNKPIGLIHRNNLTNLFFSAYGRELSGRKTIASLVDRQVLILEHDLPVEQASILISDQAGRR
KILEFIIVNKGEYQGIGSIIDLLKEITHLQINNARYANPLTLLPGNVPISKNLDQRLKEQSPFTICYVDLDHFKPYNDCY
GYEKGDQIILGVADILRDIVTDRDDFIGHIGGDDFIVILSSDHWQIQCEKILANFSEWVIHSYSPEDQERGGIASEDRTG
AKQFYPLLSLSIGCVNLSPSICNSHNDVAVLASYAKSKAKKIKGNSLYLYDSKTTANALPEKKYLTELCHSS

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=236, Percent_Identity=30.5084745762712, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI87081845, Length=234, Percent_Identity=29.4871794871795, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082096, Length=230, Percent_Identity=31.7391304347826, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787541, Length=237, Percent_Identity=27.4261603375527, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081921, Length=240, Percent_Identity=28.3333333333333, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787055, Length=231, Percent_Identity=29.8701298701299, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI226510982, Length=180, Percent_Identity=31.1111111111111, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787410, Length=217, Percent_Identity=25.3456221198157, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=26.0504201680672, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081980, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788849, Length=200, Percent_Identity=28, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786507, Length=260, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 71592; Mature: 71592

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIFICIRMGIIKPQNYSVSISLTTSCDEENMPNLTILSLDLIIQDKNLSVFFQPIVEN
CCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCEEEHHHHHHH
IERNIFGYEALIRGPFNSQLYSPIALFAAAKDQSRLVELELLCRELSILQFKKLNLQGKL
HHHHHCCHHHHEECCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FLNASPETLFQPNFRSGQTLKLLKKIDLDPSRVVIELTEHSPLENYEVIRDALKHYKEMG
EEECCCCHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
FEIAMDDLGSGYSGLRAWYELRPDYVKIDRHFMCDIDSDKVKQQFVLSIKNIAQELGCKV
CEEEEHHCCCCHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHCHHH
IAEGVETANEFRFIEKIGLRFCQGYYFKRPAPLPVRRINNNLFSERRLTAQSKNRLISSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
MVGELLQPIDAISTATTIESCATLFKQKPDLDSIPVLENNKPIGLIHRNNLTNLFFSAYG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEECCCHHHHHHHHHC
RELSGRKTIASLVDRQVLILEHDLPVEQASILISDQAGRRKILEFIIVNKGEYQGIGSII
CCCCCHHHHHHHHCCEEEEEECCCCCCHHEEEEECCCCHHHEEHHHEECCCCCCCHHHHH
DLLKEITHLQINNARYANPLTLLPGNVPISKNLDQRLKEQSPFTICYVDLDHFKPYNDCY
HHHHHHHHEEECCCCCCCCEEECCCCCCCCCCHHHHHHHCCCEEEEEEEHHHCCCCHHHC
GYEKGDQIILGVADILRDIVTDRDDFIGHIGGDDFIVILSSDHWQIQCEKILANFSEWVI
CCCCCCEEEEEHHHHHHHHHCCCCHHEEECCCCCEEEEEECCCCEEEHHHHHHHHHHHHE
HSYSPEDQERGGIASEDRTGAKQFYPLLSLSIGCVNLSPSICNSHNDVAVLASYAKSKAK
ECCCCCHHHCCCCCCCCCCCHHHHHHHHHHEEEEEECCHHHHCCCCCHHHHHHHHHHHHH
KIKGNSLYLYDSKTTANALPEKKYLTELCHSS
HCCCCEEEEEECCCCHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKAIFICIRMGIIKPQNYSVSISLTTSCDEENMPNLTILSLDLIIQDKNLSVFFQPIVEN
CCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEECCCCEEEHHHHHHH
IERNIFGYEALIRGPFNSQLYSPIALFAAAKDQSRLVELELLCRELSILQFKKLNLQGKL
HHHHHCCHHHHEECCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FLNASPETLFQPNFRSGQTLKLLKKIDLDPSRVVIELTEHSPLENYEVIRDALKHYKEMG
EEECCCCHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
FEIAMDDLGSGYSGLRAWYELRPDYVKIDRHFMCDIDSDKVKQQFVLSIKNIAQELGCKV
CEEEEHHCCCCHHHHHHHHHCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHCHHH
IAEGVETANEFRFIEKIGLRFCQGYYFKRPAPLPVRRINNNLFSERRLTAQSKNRLISSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
MVGELLQPIDAISTATTIESCATLFKQKPDLDSIPVLENNKPIGLIHRNNLTNLFFSAYG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEEECCCHHHHHHHHHC
RELSGRKTIASLVDRQVLILEHDLPVEQASILISDQAGRRKILEFIIVNKGEYQGIGSII
CCCCCHHHHHHHHCCEEEEEECCCCCCHHEEEEECCCCHHHEEHHHEECCCCCCCHHHHH
DLLKEITHLQINNARYANPLTLLPGNVPISKNLDQRLKEQSPFTICYVDLDHFKPYNDCY
HHHHHHHHEEECCCCCCCCEEECCCCCCCCCCHHHHHHHCCCEEEEEEEHHHCCCCHHHC
GYEKGDQIILGVADILRDIVTDRDDFIGHIGGDDFIVILSSDHWQIQCEKILANFSEWVI
CCCCCCEEEEEHHHHHHHHHCCCCHHEEECCCCCEEEEEECCCCEEEHHHHHHHHHHHHE
HSYSPEDQERGGIASEDRTGAKQFYPLLSLSIGCVNLSPSICNSHNDVAVLASYAKSKAK
ECCCCCHHHCCCCCCCCCCCHHHHHHHHHHEEEEEECCHHHHCCCCCHHHHHHHHHHHHH
KIKGNSLYLYDSKTTANALPEKKYLTELCHSS
HCCCCEEEEEECCCCHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]