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The map label for this gene is ppx [H]

Identifier: 119946064

GI number: 119946064

Start: 2956771

End: 2958276

Strand: Reverse

Name: ppx [H]

Synonym: Ping_2413

Alternate gene names: 119946064

Gene position: 2958276-2956771 (Counterclockwise)

Preceding gene: 119946065

Following gene: 119946062

Centisome position: 64.88

GC content: 43.69

Gene sequence:

>1506_bases
ATGTCGCAATCCGTTGAACAAAAAGTACGCAATATAGCCGCTATTGACTTGGGATCAAACAGCTTCCACATGGTAGTCGC
AAAAGTGGTGGGGCAGGATCTCCAGATGGTCAGTCGCCATAAACAGAGAGTGCGCTTAGCATCCGGGCTTGATAGTGAAA
TGAATTTAAGCGACGCTGCAATAGAACGCGGACTTTTGTGTTTGGTGATGTTTGCAGAACGTTTACAAGGATTTGAAGGT
GACAATGTGCGTATTGTCGCAACGCATGCTCTGCGCCAGGCAAATAACGCCCCTGTTTTTATCCAGCGCGCGCGCGAAGT
GTTGCCTTTCCCTATCGAAATTATTTCAGGCGAAGAAGAAGCGCGTCTTATTTATCTGGGGGTTGCCCATACACAGGTTG
AATCAGACTCCAAACTTGTTGTCGATATTGGTGGTGGCAGTACTGAAATGATCATCGGTCAGGGGTTTGAAGTTGATCTG
CTCAACAGTCAGCAAATGGGATGTGTGAGCTTTACCAATCAATTTTTTAATAATGGCAAGCTTTCTAAAAATAATTTTGC
AAAAGCAACACTGGCTGCGGAGCAACGCCTTAAGCCACTTGTCAAACAATACAGGAAAAAAGGCTGGAGCACCGCATTTG
GCTCATCAGGTACGATCAAAGCCATTAAGGAAGTACTGATTGGCTTTGGCTATCACGACGGCTTGATTACTCATAAGCGA
CTCCAAGAATTGATAGATGCACTGTGCACCTTTGACAGTATTGATGCTATCGAGCTCTCGGGATTAAGCAAAGAGCGAAA
GCCCGTTTTTGCAGCGGGTGTTGTTATTTTAAATGCACTTTTTCAAGCGTTTCAAATTATTGAAATGCATTTCTCCGATG
GTGCATTGCGGGAGGGGGTGTTGTATGAAATGGAAGCCCGTTTTGCCCGCTCAGATATCCGCATGCGCACTACCGAAAAT
TTAGCCAATAAACATAATGTTGAATTAAATCATGCAGTTTGTGTTAAGCATCAGGCGACTGAATTATTTTCCCAAATCCG
TCAAACTTTGGGTATCAAAAAGCACAGTGAGCTGCTGTCGTTATTGCAGTGGGCCGCATTGTTACATGAAGTTGGCTTAA
ATATCAGCTTACCCGGTTTTCACCGCCATTCAGCCTATATACTGCAGCATACTAATATGCCCGGTTTTAATAGTGAGCAG
CAATTAGTGCTTGCCACTCTGGCACGTTTTCAGTGTAAATCATTGAAACTGAATGAAATGCCTGAATTTAACTTGTTTGA
TAAAAACCATTTACTCGCGCTTATAAAAATACTTCGGCTGGCGATTATTCTTAATGGCCAGCGCAACGATCAGCTATTAC
CGGAAATATTATTAACCGTGGAAGGTAAGCTCTGGGTGTTGGACTGCGTTAACCAGCTGTGGCTTGAAGACAATAAATCT
CTGTATGCAGACTTGTTAGCCGAGCAAGAGCGCTGGTTAAGTGCTGGATGGCAACTTAAATTTTAA

Upstream 100 bases:

>100_bases
CGAGGAAACCGCAAAAAAATTCGCTCACAGCTCGATATTTATGAATACCTTAAAAACACCGAAAAACAAACTAGAAAACA
ACAAAAGCAGAGCCGAGATA

Downstream 100 bases:

>100_bases
GGTGCTTCTCAATCTTTTTGAACACTTAGCTTATTCTTATTCCGATCTTTGAGCCGGCATCTAGAAATGCTTTAATCAGC
CCCGTAAGTCAATATATTTA

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MSQSVEQKVRNIAAIDLGSNSFHMVVAKVVGQDLQMVSRHKQRVRLASGLDSEMNLSDAAIERGLLCLVMFAERLQGFEG
DNVRIVATHALRQANNAPVFIQRAREVLPFPIEIISGEEEARLIYLGVAHTQVESDSKLVVDIGGGSTEMIIGQGFEVDL
LNSQQMGCVSFTNQFFNNGKLSKNNFAKATLAAEQRLKPLVKQYRKKGWSTAFGSSGTIKAIKEVLIGFGYHDGLITHKR
LQELIDALCTFDSIDAIELSGLSKERKPVFAAGVVILNALFQAFQIIEMHFSDGALREGVLYEMEARFARSDIRMRTTEN
LANKHNVELNHAVCVKHQATELFSQIRQTLGIKKHSELLSLLQWAALLHEVGLNISLPGFHRHSAYILQHTNMPGFNSEQ
QLVLATLARFQCKSLKLNEMPEFNLFDKNHLLALIKILRLAIILNGQRNDQLLPEILLTVEGKLWVLDCVNQLWLEDNKS
LYADLLAEQERWLSAGWQLKF

Sequences:

>Translated_501_residues
MSQSVEQKVRNIAAIDLGSNSFHMVVAKVVGQDLQMVSRHKQRVRLASGLDSEMNLSDAAIERGLLCLVMFAERLQGFEG
DNVRIVATHALRQANNAPVFIQRAREVLPFPIEIISGEEEARLIYLGVAHTQVESDSKLVVDIGGGSTEMIIGQGFEVDL
LNSQQMGCVSFTNQFFNNGKLSKNNFAKATLAAEQRLKPLVKQYRKKGWSTAFGSSGTIKAIKEVLIGFGYHDGLITHKR
LQELIDALCTFDSIDAIELSGLSKERKPVFAAGVVILNALFQAFQIIEMHFSDGALREGVLYEMEARFARSDIRMRTTEN
LANKHNVELNHAVCVKHQATELFSQIRQTLGIKKHSELLSLLQWAALLHEVGLNISLPGFHRHSAYILQHTNMPGFNSEQ
QLVLATLARFQCKSLKLNEMPEFNLFDKNHLLALIKILRLAIILNGQRNDQLLPEILLTVEGKLWVLDCVNQLWLEDNKS
LYADLLAEQERWLSAGWQLKF
>Mature_500_residues
SQSVEQKVRNIAAIDLGSNSFHMVVAKVVGQDLQMVSRHKQRVRLASGLDSEMNLSDAAIERGLLCLVMFAERLQGFEGD
NVRIVATHALRQANNAPVFIQRAREVLPFPIEIISGEEEARLIYLGVAHTQVESDSKLVVDIGGGSTEMIIGQGFEVDLL
NSQQMGCVSFTNQFFNNGKLSKNNFAKATLAAEQRLKPLVKQYRKKGWSTAFGSSGTIKAIKEVLIGFGYHDGLITHKRL
QELIDALCTFDSIDAIELSGLSKERKPVFAAGVVILNALFQAFQIIEMHFSDGALREGVLYEMEARFARSDIRMRTTENL
ANKHNVELNHAVCVKHQATELFSQIRQTLGIKKHSELLSLLQWAALLHEVGLNISLPGFHRHSAYILQHTNMPGFNSEQQ
LVLATLARFQCKSLKLNEMPEFNLFDKNHLLALIKILRLAIILNGQRNDQLLPEILLTVEGKLWVLDCVNQLWLEDNKSL
YADLLAEQERWLSAGWQLKF

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=495, Percent_Identity=50.1010101010101, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI48994966, Length=491, Percent_Identity=39.918533604888, Blast_Score=335, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 56252; Mature: 56121

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSVEQKVRNIAAIDLGSNSFHMVVAKVVGQDLQMVSRHKQRVRLASGLDSEMNLSDAA
CCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IERGLLCLVMFAERLQGFEGDNVRIVATHALRQANNAPVFIQRAREVLPFPIEIISGEEE
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCC
ARLIYLGVAHTQVESDSKLVVDIGGGSTEMIIGQGFEVDLLNSQQMGCVSFTNQFFNNGK
CEEEEEEEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCC
LSKNNFAKATLAAEQRLKPLVKQYRKKGWSTAFGSSGTIKAIKEVLIGFGYHDGLITHKR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHH
LQELIDALCTFDSIDAIELSGLSKERKPVFAAGVVILNALFQAFQIIEMHFSDGALREGV
HHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCH
LYEMEARFARSDIRMRTTENLANKHNVELNHAVCVKHQATELFSQIRQTLGIKKHSELLS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
LLQWAALLHEVGLNISLPGFHRHSAYILQHTNMPGFNSEQQLVLATLARFQCKSLKLNEM
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PEFNLFDKNHLLALIKILRLAIILNGQRNDQLLPEILLTVEGKLWVLDCVNQLWLEDNKS
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCHH
LYADLLAEQERWLSAGWQLKF
HHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure 
SQSVEQKVRNIAAIDLGSNSFHMVVAKVVGQDLQMVSRHKQRVRLASGLDSEMNLSDAA
CCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IERGLLCLVMFAERLQGFEGDNVRIVATHALRQANNAPVFIQRAREVLPFPIEIISGEEE
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCC
ARLIYLGVAHTQVESDSKLVVDIGGGSTEMIIGQGFEVDLLNSQQMGCVSFTNQFFNNGK
CEEEEEEEEEEEECCCCEEEEEECCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCC
LSKNNFAKATLAAEQRLKPLVKQYRKKGWSTAFGSSGTIKAIKEVLIGFGYHDGLITHKR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHH
LQELIDALCTFDSIDAIELSGLSKERKPVFAAGVVILNALFQAFQIIEMHFSDGALREGV
HHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCH
LYEMEARFARSDIRMRTTENLANKHNVELNHAVCVKHQATELFSQIRQTLGIKKHSELLS
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
LLQWAALLHEVGLNISLPGFHRHSAYILQHTNMPGFNSEQQLVLATLARFQCKSLKLNEM
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PEFNLFDKNHLLALIKILRLAIILNGQRNDQLLPEILLTVEGKLWVLDCVNQLWLEDNKS
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCHH
LYADLLAEQERWLSAGWQLKF
HHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]