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The map label for this gene is glk

Identifier: 119946038

GI number: 119946038

Start: 2898894

End: 2899859

Strand: Reverse

Name: glk

Synonym: Ping_2382

Alternate gene names: 119946038

Gene position: 2899859-2898894 (Counterclockwise)

Preceding gene: 119946039

Following gene: 119946037

Centisome position: 63.6

GC content: 51.04

Gene sequence:

>966_bases
ATGAAACAGGTTAGTTTGGTCGGCGATGTGGGCGGCACTAATGCACGTCTGGCATTATGTGATCTGGAAACGGGCAGCAT
TTCTCACTCTCTGACCTATTCAGGTCTTGATTATCCCTCTCTGGAGGCTGTGGTGCGAGTCTATCTGGATCAACAATCGT
TGCGTATTGAGCAGGCATGCATTGGCATCGCCTGTCCCATTGATGGGGATCAAGTCTCGATGACTAACCATAGCTGGGCA
TTTTCAATCAAACAGATGCAGGAAAATCTTGGCCTAAAAAAGCTGACTATTATTAATGATTTTACTGCGGTATCGATGGC
GATTCCGGTGCTTGGTGCTGATGACAAAGTTCAGTTGGGAGGCGGTTTAGCCCGTTCCGGTAAACCCATTGCTGTCTACG
GGGCGGGCACGGGGCTTGGCGTTGCACATCTGGTGCAGTCTTGCGATCGCTGGTTAAGTTTACCGGGTGAAGGAGGGCAT
GTGGATATGGCGAGTTGTACTGAGCAAGAGGATGCGCTGATTCAGCAGCTGCGGCTCGAGCTGGGGCATGTTTCAGCGGA
AAGGCTGCTTTCCGGACCGGGACTGGTTAATATCTATAAGGGTTTAGTGACCTCCGATCATCGGGTGCCTGAAATATTAA
CGCCCAAGCAGATTTCAGATCGCGCGCTTTCTGGAGAGTGCCATGATTGCCATCGGGCACTGAGCCTTTTTTGTGTATTG
ATGGGACGCTTTGCCGGTAATCTGGCGCTCAATCTTGGCACTTTCGGCGGTGTTTATATTGCCGGTGGCCTAGTGCCTCG
CTTCCTTGAGTTTTTTAAAGCCTCTGGTTTCCGCGAGGCTTTTGCAGACAAAGGGCGTTTTAAAGAACATCTGGAGGCCA
TTCCCGTTTACGTAATTACCCATTCGCAGCCGGGTTTACTGGGTGCTGGCGCCTATCTGCGTCAGTCCCTGGGAATCACT
CTTTAA

Upstream 100 bases:

>100_bases
TCACTCGCGCTTGCACCCTATGAGTCTTTTGCACTGCTCATTAAGCCGTGTTAAAGAATACCGGATATATGAATAATAAG
TTTCTAATAAGGAAAATAAG

Downstream 100 bases:

>100_bases
CGGATTTGTTAGATAATTGATGACTTCTCGGTAAAATGATTTTTCATTATCGGCGGCTATTTTATAATGCTTATTTGAGT
GTGCGATACACCCCCGCGAT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKQVSLVGDVGGTNARLALCDLETGSISHSLTYSGLDYPSLEAVVRVYLDQQSLRIEQACIGIACPIDGDQVSMTNHSWA
FSIKQMQENLGLKKLTIINDFTAVSMAIPVLGADDKVQLGGGLARSGKPIAVYGAGTGLGVAHLVQSCDRWLSLPGEGGH
VDMASCTEQEDALIQQLRLELGHVSAERLLSGPGLVNIYKGLVTSDHRVPEILTPKQISDRALSGECHDCHRALSLFCVL
MGRFAGNLALNLGTFGGVYIAGGLVPRFLEFFKASGFREAFADKGRFKEHLEAIPVYVITHSQPGLLGAGAYLRQSLGIT
L

Sequences:

>Translated_321_residues
MKQVSLVGDVGGTNARLALCDLETGSISHSLTYSGLDYPSLEAVVRVYLDQQSLRIEQACIGIACPIDGDQVSMTNHSWA
FSIKQMQENLGLKKLTIINDFTAVSMAIPVLGADDKVQLGGGLARSGKPIAVYGAGTGLGVAHLVQSCDRWLSLPGEGGH
VDMASCTEQEDALIQQLRLELGHVSAERLLSGPGLVNIYKGLVTSDHRVPEILTPKQISDRALSGECHDCHRALSLFCVL
MGRFAGNLALNLGTFGGVYIAGGLVPRFLEFFKASGFREAFADKGRFKEHLEAIPVYVITHSQPGLLGAGAYLRQSLGIT
L
>Mature_321_residues
MKQVSLVGDVGGTNARLALCDLETGSISHSLTYSGLDYPSLEAVVRVYLDQQSLRIEQACIGIACPIDGDQVSMTNHSWA
FSIKQMQENLGLKKLTIINDFTAVSMAIPVLGADDKVQLGGGLARSGKPIAVYGAGTGLGVAHLVQSCDRWLSLPGEGGH
VDMASCTEQEDALIQQLRLELGHVSAERLLSGPGLVNIYKGLVTSDHRVPEILTPKQISDRALSGECHDCHRALSLFCVL
MGRFAGNLALNLGTFGGVYIAGGLVPRFLEFFKASGFREAFADKGRFKEHLEAIPVYVITHSQPGLLGAGAYLRQSLGIT
L

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=67.601246105919, Blast_Score=463, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_PSYIN (A1SXA4)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943718.1
- ProteinModelPortal:   A1SXA4
- SMR:   A1SXA4
- STRING:   A1SXA4
- GeneID:   4624035
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2382
- eggNOG:   COG0837
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- PhylomeDB:   A1SXA4
- ProtClustDB:   PRK00292
- BioCyc:   PING357804:PING_2382-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 34293; Mature: 34293

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVSLVGDVGGTNARLALCDLETGSISHSLTYSGLDYPSLEAVVRVYLDQQSLRIEQAC
CCCEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHH
IGIACPIDGDQVSMTNHSWAFSIKQMQENLGLKKLTIINDFTAVSMAIPVLGADDKVQLG
EEEECCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHEEEEECCCCCEEEC
GGLARSGKPIAVYGAGTGLGVAHLVQSCDRWLSLPGEGGHVDMASCTEQEDALIQQLRLE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCHHHHHHHHHHHH
LGHVSAERLLSGPGLVNIYKGLVTSDHRVPEILTPKQISDRALSGECHDCHRALSLFCVL
HCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHCCHHCCCCHHHHHHHHHHHHHH
MGRFAGNLALNLGTFGGVYIAGGLVPRFLEFFKASGFREAFADKGRFKEHLEAIPVYVIT
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCEEEEEE
HSQPGLLGAGAYLRQSLGITL
CCCCCCEEHHHHHHHHCCCCC
>Mature Secondary Structure
MKQVSLVGDVGGTNARLALCDLETGSISHSLTYSGLDYPSLEAVVRVYLDQQSLRIEQAC
CCCEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHH
IGIACPIDGDQVSMTNHSWAFSIKQMQENLGLKKLTIINDFTAVSMAIPVLGADDKVQLG
EEEECCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHEEEEECCCCCEEEC
GGLARSGKPIAVYGAGTGLGVAHLVQSCDRWLSLPGEGGHVDMASCTEQEDALIQQLRLE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCHHHHHHHHHHHH
LGHVSAERLLSGPGLVNIYKGLVTSDHRVPEILTPKQISDRALSGECHDCHRALSLFCVL
HCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHCCHHCCCCHHHHHHHHHHHHHH
MGRFAGNLALNLGTFGGVYIAGGLVPRFLEFFKASGFREAFADKGRFKEHLEAIPVYVIT
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCEEEEEE
HSQPGLLGAGAYLRQSLGITL
CCCCCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA