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The map label for this gene is rpiR [H]

Identifier: 119946016

GI number: 119946016

Start: 2871640

End: 2872500

Strand: Direct

Name: rpiR [H]

Synonym: Ping_2360

Alternate gene names: 119946016

Gene position: 2871640-2872500 (Clockwise)

Preceding gene: 119946013

Following gene: 119946017

Centisome position: 62.98

GC content: 39.84

Gene sequence:

>861_bases
ATGAAAACTTTAGAGTTAATTCAAAAAAATCTGGGTAGTTTCAGCAAATCAGAAAGAAAAGTGGCAGAAGTTATCATTGC
ATCACCAGAAGTCGCTATCCATTCCAGCATTGCGACACTCGCTAAAATGGCTGAAGTCAGTGAACCAACGGTTAATCGTT
TTTGCAGACGCCTTGATACTAAGGGTTTTCCTGACTTTAAATTACTGCTCGCGCAAAGTCTGGTGGTAGGTACCCCCTAT
GTGAATCGTCATGTTAATCAGGATGATGGCCCGGAAGCTTATAATGCAAAAATATTTGAATCAACCATAGCTTGTCTGGA
TTCTGCTAAAAATATGATCGACACGGCCGTCATTAAAAGAGCCGTTGAGGTGTTAACCCGAGCCGATAAAATTGCATTCT
TTGGATTGGGTGCATCCTCTGCCGTTGCCCATGATGCTTTAAATAAATTTATCCGTTTTAATATTCCCGTTTCCTGTTTT
GATGACATTGTTATGCAAAAAATGAGCTGTATTAATAGTCGTAAAGGGGATGTGATTGTTTTAATATCCCATACGGGCCG
TACTAAAGCACTCGTAGAAGTCGCGCAACTTGCGCGTGAAAATAATGCTTTTGTTATCGCATTAACACCGAATCATTCAC
CACTTGCTGAAAAAAGTAACTTGGTTCTCTCGGCCTCGGTACCAGAAGATACTGATATTTATATGCCCATGGCATCCCGT
ATTGTTCAAATGGTCATTATTGATGTTTTAGCAACGGGTTTTACATTACGCCGAGGTCCTAAATTTATTGAACATTTAAA
GCGCATCAAAACCGAGATTAAAGACTCTCGCTTTGATAAAGTTGATCTAAACGAAGACTGA

Upstream 100 bases:

>100_bases
TAATAAAATATTAATTAAGCACACCTGAGCTATCTCCCGATAGCCAATCTCGTCATTATTTACAAGTTTACCTTAAAAAT
AATTATCTTAGTGGAACAAT

Downstream 100 bases:

>100_bases
AAGTTTTACCCCTTTATACTTTTCAATAGATTAAAAACCTAACAGCAAAATAACTTTAATGACTGGAGTAGATAATGTTG
AGACGCACAAAAATTGTGAC

Product: DNA-binding transcriptional regulator HexR

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKTLELIQKNLGSFSKSERKVAEVIIASPEVAIHSSIATLAKMAEVSEPTVNRFCRRLDTKGFPDFKLLLAQSLVVGTPY
VNRHVNQDDGPEAYNAKIFESTIACLDSAKNMIDTAVIKRAVEVLTRADKIAFFGLGASSAVAHDALNKFIRFNIPVSCF
DDIVMQKMSCINSRKGDVIVLISHTGRTKALVEVAQLARENNAFVIALTPNHSPLAEKSNLVLSASVPEDTDIYMPMASR
IVQMVIIDVLATGFTLRRGPKFIEHLKRIKTEIKDSRFDKVDLNED

Sequences:

>Translated_286_residues
MKTLELIQKNLGSFSKSERKVAEVIIASPEVAIHSSIATLAKMAEVSEPTVNRFCRRLDTKGFPDFKLLLAQSLVVGTPY
VNRHVNQDDGPEAYNAKIFESTIACLDSAKNMIDTAVIKRAVEVLTRADKIAFFGLGASSAVAHDALNKFIRFNIPVSCF
DDIVMQKMSCINSRKGDVIVLISHTGRTKALVEVAQLARENNAFVIALTPNHSPLAEKSNLVLSASVPEDTDIYMPMASR
IVQMVIIDVLATGFTLRRGPKFIEHLKRIKTEIKDSRFDKVDLNED
>Mature_286_residues
MKTLELIQKNLGSFSKSERKVAEVIIASPEVAIHSSIATLAKMAEVSEPTVNRFCRRLDTKGFPDFKLLLAQSLVVGTPY
VNRHVNQDDGPEAYNAKIFESTIACLDSAKNMIDTAVIKRAVEVLTRADKIAFFGLGASSAVAHDALNKFIRFNIPVSCF
DDIVMQKMSCINSRKGDVIVLISHTGRTKALVEVAQLARENNAFVIALTPNHSPLAEKSNLVLSASVPEDTDIYMPMASR
IVQMVIIDVLATGFTLRRGPKFIEHLKRIKTEIKDSRFDKVDLNED

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=284, Percent_Identity=66.5492957746479, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI87082369, Length=239, Percent_Identity=22.5941422594142, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788767, Length=254, Percent_Identity=26.7716535433071, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082130, Length=190, Percent_Identity=27.3684210526316, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31618

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLELIQKNLGSFSKSERKVAEVIIASPEVAIHSSIATLAKMAEVSEPTVNRFCRRLDT
CCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
KGFPDFKLLLAQSLVVGTPYVNRHVNQDDGPEAYNAKIFESTIACLDSAKNMIDTAVIKR
CCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEVLTRADKIAFFGLGASSAVAHDALNKFIRFNIPVSCFDDIVMQKMSCINSRKGDVIV
HHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LISHTGRTKALVEVAQLARENNAFVIALTPNHSPLAEKSNLVLSASVPEDTDIYMPMASR
EEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEHHHHHH
IVQMVIIDVLATGFTLRRGPKFIEHLKRIKTEIKDSRFDKVDLNED
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKTLELIQKNLGSFSKSERKVAEVIIASPEVAIHSSIATLAKMAEVSEPTVNRFCRRLDT
CCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
KGFPDFKLLLAQSLVVGTPYVNRHVNQDDGPEAYNAKIFESTIACLDSAKNMIDTAVIKR
CCCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEVLTRADKIAFFGLGASSAVAHDALNKFIRFNIPVSCFDDIVMQKMSCINSRKGDVIV
HHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LISHTGRTKALVEVAQLARENNAFVIALTPNHSPLAEKSNLVLSASVPEDTDIYMPMASR
EEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEHHHHHH
IVQMVIIDVLATGFTLRRGPKFIEHLKRIKTEIKDSRFDKVDLNED
HHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]